James J Palmer

US Patent:

8461106, Jun 11, 2013

Filed:

Jul 9, 2008

Appl. No.:

12/668489

Inventors:

Noam A Cohen - Bala Cynwyd PA, US
Alexander G. Chiu - Villanova PA, US
James N. Palmer - Narberth PA, US
Jacob D. Steiger - Highland Beach FL, US

Assignee:

The Trustees of the University of Pennsylvania - Philadelphia PA

International Classification:

A61K 38/40

US Classification:

514 25

Abstract:

This invention relates to methods and compositions capable of inhibiting biofilm formation. Specifically, provided herein are methods and compositions using Lactoferrin for the inhibition of biofilm formation.

US Patent:

20110172704, Jul 14, 2011

Filed:

Sep 18, 2009

Appl. No.:

13/119659

Inventors:

Benjamin S. Bleier - Villanova PA, US
Noam A. Cohen - Bala cynwyd PA, US
James N. Palmer - Philadelphia PA, US

Assignee:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - PHILADELPHIA PA

International Classification:

A61B 17/00
A61K 38/38
A61P 17/02

US Classification:

606213, 514 152

Abstract:

Supersaturated gel formulations including a solution of chitosan, albumin, and a laser specific chromophore. Laser tissue welding methods using the gel formulations of the present invention are also described. In the methods, the gel formulation of the present invention is provided to a site for tissue repair and the laser specific chromophore within the gel is excited with a laser in order to fuse tissue by inducing protein denaturation. The gel formulations and laser tissue welding methods may be used, for example, to enable skull base repairs, aerodigestive endoscopic repairs, endoscopic endonasal surgical repairs, iatrogenic esophageal perforation repairs, laparoscopic abdominal surgical repairs, lung repairs, colon repairs, anastomosis of vessels, urologic/gynecologic endoscopic pelvic repairs, orofacial surgical repairs, dental replacement, skin closure, uterine closure and repairs after fibroidectomies and bladder surgery.

US Patent:

46305220, Dec 23, 1986

Filed:

Mar 1, 1985

Appl. No.:

6/707492

Inventors:

James E. Palmer - Berwyn PA
Rocco D. Albertini - Media PA
Michael A. Coladonato - Havertown PA

Assignee:

Baldt Incorporated - Chester PA

International Classification:

F41F 500

US Classification:

89 114

Abstract:

An accoustically detonated explosively separable link comprising a pair of bolt assemblies mounted in spaced operative relation within the separable link parts, each of which includes a bolt having a cavity therein. An explosive is provided in each cavity and an electrically actuated exploding bridge wire is connected with each explosive for detonating the same. A miniaturized acoustical receiver assembly is mounted within the link parts and includes a hydrophone for receiving a transmitted acoustical detonation signal, batteries and circuitry operatively connected with the hydrophone, the batteries and exploding bridge wires for conducting an electrical current from the batteries to the exploding bridge wires in response to the hydrophone receiving a transmitted acoustical detonation signal. A water pressure resistant container is mounted within the link parts between the pair of spaced bolt assemblies for containing the batteries and circuitry including the operative connections thereof free from contact with water under pressure and for retaining the hydrophone in a position of proximity to water under pressure such as to receive an acoustical detonation signal transmitted through the water under pressure.

US Patent:

20230013755, Jan 19, 2023

Filed:

Jun 2, 2022

Appl. No.:

17/830714

Inventors:

- Beerse, BE
Ivo CORNELISSEN - Turnhout, BE
Yue GUO - North Wales PA, US
Jocelyn H. LEU - Lower Gwynedd PA, US
Kathryn E. PACKMAN - Newton MA, US
James Alexander PALMER - San Diego CA, US
Ulrike PHILIPPAR - Antwerpen, BE
Navin RAO - Maple Glen PA, US
Mark S. TICHENOR - San Diego CA, US
Jennifer D. VENABLE - Solana Beach CA, US
John J. M. WIENER - La Jolla CA, US
Xin MIAO - Blue Bell PA, US

International Classification:

A61K 31/519
A61P 35/00

Abstract:

The present disclosure is directed to the use of a compound of Formula (III) in the treatment of malignancies.

US Patent:

20210260144, Aug 26, 2021

Filed:

Apr 21, 2021

Appl. No.:

17/236918

Inventors:

- Philadelphia PA, US
- Seoul, KR
Joel N. Maslow - Devon PA, US
Christine C. Roberts - Zionsville PA, US
Sara Cherry - Philadelphia PA, US
Michael Kohanski - Penn Valley PA, US
Nithin D. Adappa - Philadelphia PA, US
James N. Palmer - Penn Valley PA, US
Li Hui Tan - Philadelphia PA, US

Assignee:

The Trustees of the University of Pennsylvania - Philadelphia PA
Monell Chemical Senses Center - Philadelphia PA
GeneOne Life Science, Inc. - Seoul

International Classification:

A61K 36/185
G01N 33/68
G01N 33/566
A61K 31/167
A61K 31/365
A61K 31/4709
A61K 31/513
A61K 45/06
C12Q 1/6883
G01N 33/50

Abstract:

The invention provides methods and compositions for assaying infectivity of viruses and potential treatments of such viruses in the upper respiratory tract using an air-liquid interface model with nasal epithelium cells; and treatment of viral infections of the upper respiratory tract by treating with bitter taste receptor agonists that stimulate NO production and/or antimicrobial protein production.