Frederick VanGoor - San Diego CA, US Sara Ruah - La Jolla CA, US Ashvani Singh - San Diego CA, US Eric Olson - Belmont MA, US Lewis Makings - Encinitas CA, US Jesus Gonzalez - San Diego CA, US James Rader - La Jolla CA, US Fred Chambers - San Diego CA, US Mark Miller - San Diego CA, US Peter Grootenhuis - San Diego CA, US Yahua Liu - San Diego CA, US
International Classification:
A61K031/4162 A61K031/4439 A61K031/415
US Classification:
514341000, 514406000
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Frederick F. VanGoor - San Diego CA, US Sara Sabina Hadida Ruah - La Jolla CA, US Ashvani Kumar Singh - San Diego CA, US Eric R. Olson - Belmont MA, US Lewis Ray Makings - Encinitas CA, US James Arvid Rader - La Jolla CA, US Fred Chambers, III - San Diego CA, US Mark Thomas Miller - San Diego CA, US Peter Diederik Jan Grootenhuis - San Diego CA, US Yahua Liu - San Diego CA, US
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED - Cambridge MA
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Frederick F. Van Goor - San Diego CA, US Ashvani Kumar Singh - San Diego CA, US Eric R. Olson - Belmont MA, US Lewis Ray Makings - Encinitas CA, US James Arvid Rader - La Jolla CA, US Fred Chambers, III - San Diego CA, US Mark Thomas Miller - San Diego CA, US Peter Diederik Jan Grootenhuis - San Diego CA, US Yahua Liu - San Diego CA, US
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED - Cambridge MA
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.