James Francis Russo

US Patent:

6348586, Feb 19, 2002

Filed:

Nov 17, 1999

Appl. No.:

09/230371

Inventors:

Yuan Chang - Irvington NY
Roy A. Bohenzky - Mountain View CA
James J. Russo - New York NY
Isidore S. Edelman - New York NY
Patrick S. Moore - Irvington NY

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

A61K 39245

US Classification:

536 2372, 4242311, 4241861, 4242291, 435325, 4353201, 4352351, 435 6, 514 44, 536 231, 536 241, 536 2432, 536 2433, 530350

Abstract:

This invention provides an isolated nucleic acid molecule which encodes Kaposis Sarcoma-Associated Herpesvirus (KSHV) polypeptides. This invention provides an isolated polypeptide molecule of KSHV. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposis Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposis sarcoma in a cell.

US Patent:

6627748, Sep 30, 2003

Filed:

Sep 11, 2000

Appl. No.:

09/658077

Inventors:

Jingyue Ju - Englewood Cliffs NJ
Zengmin Li - New York NY
Anthony Tong - New York NY
James J. Russo - New York NY

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C07H 2100

US Classification:

536 2532, 435 4, 435 6, 435 71, 435DIG 41, 435 911, 436501, 436518, 536 231, 536 243, 530323, 530345

Abstract:

This invention provides a combinatorial fluorescence energy transfer tag which comprises a plurality of fluorescent molecules, comprising one or more energy transfer donor and one or more energy transfer acceptor, linked through a molecular scaffold wherein the fluorescent molecules are separated along the scaffold to produce a unique fluorescence emission signature. The invention further provides for the use of said tags in multi-component analyses, including multiplex genetic analyses.

US Patent:

20060057565, Mar 16, 2006

Filed:

Sep 11, 2001

Appl. No.:

10/380256

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Zengmin Li - New York NY, US
Anthony Tong - New York NY, US
James Russo - New York NY, US

International Classification:

C40B 40/08
C40B 40/10

US Classification:

435006000, 435007100

Abstract:

This invention provides a combinatorial fluorescence energy transfer tag which comprises a plurality of fluorescent molecules, comprising one or more energy transfer donor and one or more energy transfer acceptor, linked through a molecular scaffold wherein the fluorescent molecules are separated along the scaffold to produce a unique fluorescene emission signature. The invention further provides for the use of said tags in multi-component analyses, including multiplex biological analyses.

US Patent:

20130264207, Oct 10, 2013

Filed:

Dec 16, 2011

Appl. No.:

13/994431

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Shiv Kumar - Belle Mead NJ, US
Zengmin Li - Flushing NY, US
Minchen Chien - Tenafly NJ, US
James J. Russo - New York NY, US
Sergey Kalachikov - New York NY, US
Ken Shepard - Ossining NY, US
Jacob Karl Rosenstein - New York NY, US

International Classification:

C12Q 1/68
C07H 21/00
C07H 19/10

US Classification:

204452, 536 256, 536 2622, 536 2626, 536 2621

Abstract:

This disclosure is related to a method of sequencing a single-stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.

US Patent:

20220411860, Dec 29, 2022

Filed:

Jul 12, 2021

Appl. No.:

17/373295

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Xiaoxu Li - New York NY, US
Xin Chen - New York NY, US
Zengmin Li - Flushing NY, US
Shiv Kumar - Belle Meade NJ, US
Shundi Shi - Ozone Park NY, US
Cheng Guo - Brooklyn NY, US
Jianyi Ren - New York NY, US
Minchen Chien - Tenafly NJ, US
Chuanjuan Tao - Fort Lee NJ, US
Ece Erturk - New York NY, US
Sergey Kalachikov - Bronx NY, US
James J. Russo - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/6869
C07H 19/10
C07H 19/14
C07H 19/20

Abstract:

Disclosed herein, inter alfa, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

US Patent:

20220213542, Jul 7, 2022

Filed:

Apr 2, 2020

Appl. No.:

17/600593

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Shiv Kumar - Belle Mead NJ, US
James Russo - New York NY, US
Xiaoxu Li - New York NY, US
Steffen Jockusch - New York NY, US
Minchen Chien - Tenafly NJ, US
Chuanjuan Tao - Fort Lee NJ, US

Assignee:

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY

International Classification:

C12Q 1/6869
C12Q 1/6848

Abstract:

The invention provides nucleotide analogues and methods of use thereof for sequencing by synthesis using energy transfer dye pairs.

US Patent:

20220177959, Jun 9, 2022

Filed:

Mar 5, 2020

Appl. No.:

17/436513

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Carl W. Fuller - Berkeley Heights NJ, US
Shiv Kumar - Belle Mead NJ, US
Sergey Kalachikov - Bronx NY, US
Xiaoxu Li - New York NY, US
Irina Morozova - Bronx NY, US
James Russo - New York NY, US
Steffen Jockusch - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/6869

Abstract:

Disclosed herein are highly accurate approaches for single molecule electronic nanopore-based SBS.

US Patent:

20210285041, Sep 16, 2021

Filed:

Mar 28, 2018

Appl. No.:

16/498132

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Xiaoxu Li - New York NY, US
Xin Chen - New York NY, US
Shiv Kumar - Belle Mead NJ, US
James Russo - New York NY, US
Minchen Chien - Tenafly NJ, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/6869
C07H 19/10
C07H 19/20

Abstract:

Disclosed herein, inter alia, are nucleotide analogues, and methods of use thereof, having cleavable orthogonal linkers.