James M Snyder

US Patent:

39473457, Mar 30, 1976

Filed:

Nov 15, 1974

Appl. No.:

5/524069

Inventors:

Joseph D. Grandine - Acton MA
Nat H. Marsh - Nashua NH
James E. Snyder - Brighton MA

Assignee:

Millipore Corporation - Bedford MA

International Classification:

G01N 2726
G01N 2728

US Classification:

204299R

Abstract:

Apparatus for producing electrophoretic migration in an agarose gel slide which includes a slide mounting block containing a salt which maintains slide temperature during electrophoresis processing.

US Patent:

50735624, Dec 17, 1991

Filed:

May 10, 1990

Appl. No.:

7/521777

Inventors:

Stevan W. Djuric - Glenview IL
Thomas D. Penning - Elmhurst IL
James P. Snyder - Glenview IL

Assignee:

G. D. Searle & Co. - Chicago IL

International Classification:

C07D41912
A61K 31425

US Classification:

514365

Abstract:

This invention relates to compounds of Formula I and the stereoisomers and pharmaceutically acceptable salts thereof ##STR1## wherein R is alkyl, alkenyl, alkynyl, or (CH. sub. 2). sub. m R. sup. 3 where R. sup. 3 is cycloalkyl and m is 1 or 2; R. sup. 1 is alkyl; R. sup. 2 is hydrogen or alkyl; R. sup. 4 is alkyl; n is an integer from 1 to 5; p is an integer from 0 to 6; Y is NH, oxygen or sulfur; and Z is hydrogen, alkyl, alkenoxy, NR. sup. 4 R. sup. 5 wherein R. sup. 4 and R. sup. 5 are independently hydrogen or alkyl, or SR. sup. 6 wherein R. sup. 6 is hydrogen, benzyl or alkyl. The compounds of Formula I are leukotriene B. sub. 4 antagonists and are useful as anti-inflammatory agents and in the treatment of leukotriene B. sub. 4 mediated conditions.

US Patent:

51927829, Mar 9, 1993

Filed:

Sep 13, 1991

Appl. No.:

7/759272

Inventors:

Stevan W. Djuric - Glenview IL
Thomas D. Penning - Elmhurst IL
James P. Snyder - Glenview IL

Assignee:

G. D. Searle & Co. - Chicago IL

International Classification:

C07D41312
A61K 3142

US Classification:

514376

Abstract:

This invention relates to compounds of Formula I and the stereoisomers and pharmaceutically acceptable salts thereof ##STR1## wherein R is alkyl, alkenyl, alkynyl, or (CH. sub. 2). sub. m R. sup. 3 where R. sup. 3 is cycloalkyl and m is 1 or 2; R. sup. 1 is alkyl; R. sup. 2 is hydrogen or alkyl; R. sup. 4 is alkyl; n is an integer from 1 to 5; p is an integer from 0 to 6; Y is oxygen; and Z is hydrogen, alkyl, alkoxy, NR. sup. 4 R. sup. 5 wherein R. sup. 4 and R. sup. 5 are independently hydrogen or alkyl, or SR. sup. 6 wherein R. sup. 6 is hydrogen, benzyl or alkyl. The compounds of Formula I are leukotriene B. sub. 4 antagonists and are useful as anti-inflammatory agents and in the treatment of leukotriene B. sub. 4 mediated conditions.

US Patent:

39356469, Feb 3, 1976

Filed:

Nov 15, 1974

Appl. No.:

5/524364

Inventors:

Joseph D. Grandine - Acton MA
James E. Snyder - Brighton MA

Assignee:

Millipore Corporation - Bedford MA

International Classification:

F26B 1900

US Classification:

34 92

Abstract:

Apparatus for rapidly and conveniently drying an agarose gel slide following electrophoresis is provided which utilizes both vacuum and heated air to remove moisture from the slide.

US Patent:

54911788, Feb 13, 1996

Filed:

Aug 19, 1994

Appl. No.:

8/293613

Inventors:

Raymond J. Swedo - Mt. Prospect IL
George D. Green - Cary IL
James R. Snyder - Chicago IL

Assignee:

AlliedSignal Inc. - Morris Township, Morris County NJ

International Classification:

C08K 5134
C08K 536
C08K 5098
C08L 6700

US Classification:

522 74

Abstract:

This invention relates to vinyl ether-based coatings for which properties such as color stability, thermal stability, mechanical stability, hydrolytic stability, and resistance to embrittlement may be maintained and properties hydrogen generation and blocking are minimized. The coatings comprise a vinyl ether-containing composition polymerizable by actinic, gamma ray, or electron beam radiation comprising: (a) an oligomer or a mixture of oligomers which are monofunctional, multifunctional, or a mixture of both monofunctional and multifunctional and which have a reactive functionality chosen from the group consisting of epoxy, acrylate, vinyl ether, maleate, or mixtures thereof; (b) monomers which are monofunctional, multifunctional, or a mixture of both monofunctional and multifunctional monomers and which have a reactive functionality chosen from the group consisting of epoxy, acrylate, vinyl ether, maleate, or mixtures thereof, wherein at least one of (a) or (b) must contain a vinyl ether functionality; (c) a photoinitiator, optionally including a sensitizer, chosen from the group consisting of a cationic photoinitiator and a radical photoinitiator; and (d) a thermal oxidation stabilizer. The composition also comprises additives including as hydrogen stabilizers; mixtures of hindered phenols, organic sulfides or disulfides, and transition metal salts of organic compounds.

US Patent:

55147275, May 7, 1996

Filed:

Jul 13, 1994

Appl. No.:

8/274671

Inventors:

George D. Green - Cary IL
James R. Snyder - Chicago IL
Raymond J. Swedo - Mt. Prospect IL

Assignee:

AlliedSignal Inc. - Morris Township, Morris County NJ

International Classification:

C08K 513
C08K 5375
C08L 7100

US Classification:

522 15

Abstract:

This invention relates to vinyl ether-based coatings for which properties such as color stability, thermal stability, mechanical stability, hydrolyric stability, and resistance to embrittlement may be maintained and properties hydrogen generation and blocking are minimized. The invention also relates to stabilizers which control these properties in the coatings. The coatings comprise a vinyl ether-containing composition polymerizable by actinic, gamma ray, or electron beam radiation comprising: (a) an oligomer or a mixture of oligomers which are monofunctional, multifunctional, or a mixture of both monofunctional and multifunctional and which have a reactive functionality chosen from the group consisting of epoxy, acrylate, vinyl ether, maleate, or mixtures thereof, (b) monomers which are monofunctional, multifunctional, or a mixture of both monofunctional and multifunctional monomers and which have a reactive functionality chosen from the group consisting of epoxy, acrylate, vinyl ether, maleate, or mixtures thereof, wherein at least one of (a) or (b) must contain a vinyl ether functionality; (c) a photoinitiator with an optional sensitizer, said photoinitiator which is chosen from the group consisting of a cationic photoinitiator and a radical photoinitiator; and (d) a thermal oxidation stabilizer. The composition also comprises additives comprising at least one additive chosen from the group consisting of: (e) a hydrogen stabilizer; (f) a light screen; (g) a color stabilizer; (h) a blocking stabilizer or slip agent; and (j) a coupling agent.

US Patent:

52868354, Feb 15, 1994

Filed:

Aug 24, 1992

Appl. No.:

7/935078

Inventors:

George D. Green - Park Ridge IL
James R. Snyder - Chicago IL
Darryl K. Barnes - Bellwood IL

Assignee:

Allied-Signal Inc. - Morris Township, Morris County NJ

International Classification:

C08G 6347

US Classification:

528272

Abstract:

Vinyl ether terminated ester oligomers having a range of molecular weights are prepared by reacting a vinyl ether terminated polybasic ester with a polyol in the presence of a catalyst. Continual removal of a hydroxy monovinyl ether avoids formation compounds containing acetal moieties. Alternatively, a polybasic ester is chain extended with a polyol with continual removal of the alcohol by-product. Then, the terminal ester moieties are end capped with a monohydroxy vinyl ether. The oligomers have application in coatings and the like.

US Patent:

56726759, Sep 30, 1997

Filed:

Apr 10, 1996

Appl. No.:

8/630188

Inventors:

George David Green - Cary IL
James Ronald Snyder - Chicago IL
Raymond John Swedo - Mt. Prospect IL

Assignee:

AlliedSignal, Inc. - Morris Township NJ

International Classification:

C08G 63137
C08F 250
C08L 6707

US Classification:

528307

Abstract:

Oligomers of particular usefulness in coatings are vinyl ether terminated polyester oligomers which include 4,8-bis(hydroxymethyl) tricyclo�5. 2. 1. sup. 2,6 !decane (BHTD).