Peter DEVRIES - Des Plaines IL, US David OSTROW - Lake Zurich IL, US Edward REILLY - Libertyville IL, US Larry GREEN - San Francisco CA, US James WEILER - Beverly MA, US
Assignee:
ABBOTT LABORATORIES - Abbott Park IL
International Classification:
A61K 39/40 A61P 43/00 C07H 21/04 C07K 16/00
US Classification:
424137100, 530300000, 530387900, 536022100
Abstract:
The present invention relates to antibodies and antibody fragments thereof that bind to and activate an erythropoietin receptor. The present invention also relates to methods of modulating the endogenous activity of an erythropoietin receptor in a mammal using said antibodies as well as pharmaceutical compositions containing said antibodies.