Jan R Turner

US Patent:

6521406, Feb 18, 2003

Filed:

Jun 23, 2000

Appl. No.:

09/603207

Inventors:

Richard H. Baltz - Indianapolis IN
M. Christine Broughton - Indianapolis IN
Kathryn P. Crawford - Indianapolis IN
Krishnamurthy Madduri - Woodlawn OH
Donald J. Merlo - Carmel IN
Patti J. Treadway - Greenwood IN
Jan R. Turner - Carmel IN
Clive Waldron - Indianapolis IN

Assignee:

Dow AgroSciences LLC - Indianapolis IN

International Classification:

C12Q 168

US Classification:

435 6, 4353201, 4352523, 435325, 43525411, 435419, 536 232

Abstract:

Spinosyn biosynthetic genes from , spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms are provided.

US Patent:

7015001, Mar 21, 2006

Filed:

Dec 23, 2002

Appl. No.:

10/329148

Inventors:

Richard H. Baltz - Indianapolis IN, US
M. Christine Broughton - Indianapolis IN, US
Kathryn P. Crawford - Indianapolis IN, US
Krishnamurthy Madduri - Woodlawn OH, US
Donald J. Merlo - Carmel IN, US
Patti J. Treadway - Greenwood IN, US
Jan R. Turner - Carmel IN, US
Clive Waldron - Indianapolis IN, US

Assignee:

Dow AgroSciences LLC - Indianapolis IN

International Classification:

C12Q 1/68

US Classification:

435 6, 4353201, 4352523, 43525411, 435325, 435419, 536 231, 536 232

Abstract:

Spinosyn biosynthetic genes from spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms are provided.

US Patent:

55390897, Jul 23, 1996

Filed:

Sep 7, 1994

Appl. No.:

8/301835

Inventors:

Mary C. Broughton - Indianapolis IN
Lawrence Creemer - Indianapolis IN
Mary L. B. Huber - Danville IN
Herbert A. Kirst - Indianapolis IN
Jan R. Turner - Carmel IN

Assignee:

DowElanco - Indianapolis IN

International Classification:

C07H 1708
C07D30500

US Classification:

536 65

Abstract:

A83543 Aglycones A83543AgA, A83543AgD, A83543AgE, and A83543AgF, and A83543 pseudoaglycones A83543PsaA2, A83543PsaB2, A83543PsaD2, and A83543PsaN2 are intermediates useful in preparation of known insecticides.

US Patent:

45229198, Jun 11, 1985

Filed:

Mar 3, 1983

Appl. No.:

6/471928

Inventors:

Barbara B. Shreve - Indianapolis IN
Jan R. Turner - Carmel IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C12P 1718
C12R 1465

US Classification:

435119

Abstract:

Improved bioconverting strain of Streptomyces thermotolerans useful in preparing tylosin esters and new antibacterial macrocin or lactenocin ester derivatives of the formula: ##STR1## wherein R is formyl or hydroxymethyl; R. sup. 1 is hydrogen, acetyl or propionyl; R. sup. 2 is hydrogen or ##STR2## and R. sup. 3 is hydrogen, acetyl, propionyl, n-butyryl or isovaleryl; provided that one of R. sup. 1 or R. sup. 3 must be other than hydrogen.

US Patent:

62743503, Aug 14, 2001

Filed:

Aug 9, 1999

Appl. No.:

9/370700

Inventors:

Richard H. Baltz - Indianapolis IN
Kathryn P. Crawford - Indianapolis IN
M. Christine Broughton - Indianapolis IN
Krishnamurthy Madduri - Woodlawn OH
Donald J. Merlo - Carmel IN
Jan R. Turner - Carmel IN
Patti J. Treadway - Greenwood IN
Clive Waldron - Indianapolis IN

Assignee:

Dow AgroSciences LLC - Indianapolis IN

International Classification:

C12P 1962

US Classification:

435 76

Abstract:

Spinosyn biosynthetic genes, spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms.

US Patent:

56704860, Sep 23, 1997

Filed:

Jun 7, 1995

Appl. No.:

8/483440

Inventors:

Jon S. Mynderse - Indianapolis IN
James A. Mabe - Hendersonville NC
Jan R. Turner - Carmel IN
Mary L. B. Huber - Danville IN
Mary C. Broughton - Indianapolis IN
Walter M. Nakatsukasa - Seattle WA
Lawrence Creemer - Indianapolis IN
Herbert A. Kirst - Indianapolis IN
James W. Martin - Coatesville IN

Assignee:

DowElanco - Indianapolis IN

International Classification:

A61K 3171
C07H 1704
C12P 1962

US Classification:

514 28

Abstract:

New A83543 components, including fermentation products A83543K, A83543O, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.

US Patent:

46562583, Apr 7, 1987

Filed:

Jun 11, 1985

Appl. No.:

6/743243

Inventors:

Jan R. Turner - Carmel IN
Veronica M. Krupinski - Greenwood IN
David S. Fukuda - Brownsburg IN
Richard H. Baltz - Indianapolis IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

C07H 1708

US Classification:

536 71

Abstract:

New macrocin and lactenocin ester derivatives of the formula: ##STR1## wherein R is formyl or hydroxymethyl; R. sup. 1 is hydrogen, acetyl or propionyl; R. sup. 2 is hydrogen or ##STR2## and R. sup. 3 is hydrogen, acetyl, propionyl, n-butyryl or isovaleryl; provided that one of R. sup. 1 or R. sup. 3 must be other than hydrogen; and the acid addition salts thereof; prepared by bioconversion of macrocin or lactenocin with an acylating enzyme system produced by Streptomyces thermotolerans strains, have improved activity against Mycoplasma species.

US Patent:

44926936, Jan 8, 1985

Filed:

Apr 12, 1983

Appl. No.:

6/484129

Inventors:

Larry C. Blaszczak - Indianapolis IN
Stjepan Kukolja - Carmel IN
Jan R. Turner - Carmel IN

Assignee:

Eli Lilly and Company - Indianapolis IN

International Classification:

A61K 31545
C07D50122

US Classification:

424246

Abstract:

7-(3-Benzothienyl)glycylamido cephalosporins have good gram positive activity and favorable pharmacokinetics and are orally effective.