Janice L Johnson

Address:

1005 W Jasmine Dr, Salt Lake Cty, UT 84123

VIN:

1N4BA41E77C848768

Make:

NISSAN

Model:

MAXIMA

Year:

2007

US Patent:

7125847, Oct 24, 2006

Filed:

Mar 26, 2003

Appl. No.:

10/397595

Inventors:

Frederick Sachs - Eden NY, US
Thomas Suchyna - Amherst NY, US
Janice Johnson - Salt Lake City UT, US

Assignee:

The Research Foundation of State University of New York at Buffalo - Amherst NY

International Classification:

A61K 38/00
A61K 38/16
C07K 14/00
C07K 1/00

US Classification:

514 12, 530300, 530324, 514 2

Abstract:

The present invention discloses a peptide of SEQ ID NO:2 and its variants that blocks stretch-activated ion channels. The peptide, designated as GsMTx-4, is present in the venom of the spider. The present invention also discloses a method of purifying the peptide GsMTx-4 from the spider venom and a method for inhibition of stretch activated ion channels in a cell. The cDNA sequence encoding the GsMTx-4 is also disclosed. This peptide and its variants can be used for the treatment of cardiac arrhythmias.

US Patent:

20020077286, Jun 20, 2002

Filed:

Apr 6, 2001

Appl. No.:

09/827814

Inventors:

Frederick Sachs - Eden NY, US
Janice Johnson - Salt Lake City UT, US
Thomas Suchyna - Amherst NY, US

International Classification:

A61K038/17
C07K014/435

US Classification:

514/012000, 530/350000

Abstract:

The present invention discloses a 35 amino acid peptide (SEQ ID NO: 1) that blocks stretch-activated ion channels. The peptide, designated as GsMTx-4, is present in the venom of the spider The present invention also discloses a method of purifying the peptide GsMTx-4 from the spider venom and a method for inhibition of stretch activated ion channels in a cell. This peptide can be used for the treatment of cardiac arrhythmias.

US Patent:

57564590, May 26, 1998

Filed:

Jun 7, 1995

Appl. No.:

8/484357

Inventors:

John Randolph Hunter Jackson - Salt Lake City UT
Eric DelMar - Salt Lake City UT
Janice Helen Johnson - Salt Lake City UT
Robert Marden Kral - Salt Lake City UT

Assignee:

FMC Corporation - Philadelphia PA
NPS Pharmaceuticals, Inc. - Salt Lake City UT

International Classification:

A61K 3816
C07K 14435

US Classification:

514 12

Abstract:

This invention provides a family of insecticidally effective proteins and particular members of that family which may be isolated from the venom of the spider Phidippus audax, DNA encoding such proteins, insecticidal compositions of these proteins or the DNA encoding them, and methods for controlling invertebrate pests. Recombinant expression vectors and host cells and methods for producing insecticidally effective peptides are also provided.

US Patent:

61565393, Dec 5, 2000

Filed:

Feb 22, 1999

Appl. No.:

9/255119

Inventors:

Janice H. Johnson - Salt Lake City UT
Robert M. Kral - Salt Lake City UT
Karen Krapcho - Salt Lake City UT

Assignee:

NPS Pharmaceuticals, Inc. - UT

International Classification:

C12P 2106
C07H 1700
C07K 1400

US Classification:

435 691

Abstract:

This invention relates to the purification of a group of insecticidally effective toxins isolated from the wasp, Bracon hebetor, characterized by their neurotoxic effect on insect pest and low mammalian toxicity. The cDNA sequences for two of these toxins have been isolated, and the complete coding sequence is provided. This invention also discloses methods for producing recombinant toxins, as well as methods of utilizing these toxins as insecticidal agents.

US Patent:

54419344, Aug 15, 1995

Filed:

Dec 20, 1993

Appl. No.:

8/171383

Inventors:

Karen J. Krapcho - Salt Lake City UT
John R. H. Jackson - Salt Lake City UT
Janice H. Johnson - Salt Lake City UT
Eric G. DelMar - Salt Lake City UT
Robert M. Kral - Salt Lake City UT

Assignee:

FMC Corporation - Philadelphia PA
NPS Pharmaceuticals, Inc. - Salt Lake City UT

International Classification:

C12N 1509
C12P 2100
A61K 3800
A01N 6300

US Classification:

514 12

Abstract:

This invention provides a family of insecticidally effective peptides which may be isolated from Tegenaria spider venom, DNA encoding such insecticidally effective peptides and methods for controlling invertebrate pests.

US Patent:

56959591, Dec 9, 1997

Filed:

Jun 1, 1995

Appl. No.:

8/457272

Inventors:

John Randolph Hunter Jackson - Salt Lake City UT
Karen Joanne Krapcho - Salt Lake City UT
Janice Helen Johnson - Salt Lake City UT
Robert Marden Kral - Midvale UT

Assignee:

FMC Corporation - Philadelphia PA
NPS Pharmaceuticals, Inc. - Salt Lake City UT

International Classification:

C12P 2102
C12N 1563
C12N 121
A61K 31715

US Classification:

435 691

Abstract:

This invention provides a family of insecticidally effective proteins and particular members of that family which may be isolated from the venom of the spider Filistata hibernalis, DNA encoding such proteins, insecticidal compositions of these proteins or the DNA encoding them, and methods for controlling invertebrate pests. Recombinant expression vectors and host cells and methods for producing insecticidally effective peptides are also provided.

US Patent:

56887647, Nov 18, 1997

Filed:

Feb 17, 1995

Appl. No.:

8/390882

Inventors:

Janice H. Johnson - Salt Lake City UT
Robert M. Kral - Salt Lake City UT
Karen Krapcho - Salt Lake City UT

Assignee:

NPS Pharmaceuticals, Inc. - Salt Lake City UT

International Classification:

A01N 3718
C07K 14435
C12N 100
C12N 510
C12N 1512
C12N 1563

US Classification:

514 12

Abstract:

This invention relates to the purification of a family of insecticidally effective peptides isolated from the spider, Calisoga sp. , characterized by their neurotoxic effect on insect pest and low mammalian toxicity. The cDNA sequences for three of these peptides have been isolated, and the complete coding sequence is provided. This invention also discloses methods for producing recombinant peptides, as well as methods of utilizing these peptides as insecticidal agents.

US Patent:

56748469, Oct 7, 1997

Filed:

Sep 4, 1996

Appl. No.:

8/706278

Inventors:

Janice H. Johnson - Salt Lake City UT
Robert M. Kral - Salt Lake City UT

Assignee:

NPS Pharmaceuticals, Inc. - Salt Lake City UT

International Classification:

A01N 3718
C07K 14435

US Classification:

514 12

Abstract:

This invention relates to an insecticidally effective peptide isolated from the spider, Segestria sp. , characterized by its paralytic effect on insect pests and low mammalian toxicity. This invention also discloses methods for producing recombinant peptides, as well as methods of utilizing these peptides as insecticidal agents.