Yong He - Bedford MA, US Ning Yin - Lexington MA, US Dylan C. Alexander - Watertown MA, US Jason B. Cross - Acton MA, US Robert Busch - Wakefield MA, US
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
1,3,4-Oxadiazole And 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
Yong He - Bedford MA, US Ning Yin - Lexington MA, US Dylan C. Alexander - Watertown MA, US Jason B. Cross - Acton MA, US Robert Busch - Wakefield MA, US
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
1,3,4-Oxadiazole And 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
Yong He - Bedford MA, US Ning Yin - Lexington MA, US Dylan C. Alexander - Watertown MA, US Jason B. Cross - Acton MA, US Robert Busch - Wakefield MA, US
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
1,3,4-Oxadiazole And 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
Yong He - Bedford MA, US Ning Yin - Lexington MA, US Dylan C. Alexander - Watertown MA, US Jason B. Cross - Acton MA, US Robert Busch - Wakefield MA, US
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
Yong He - Bedford MA, US Ning Yin - Lexington MA, US Dylan C. Alexander - Watertown MA, US Jason B. Cross - Acton MA, US Robert Busch - Wakefield MA, US Roland E. Dolle - Hopkinton MA, US
International Classification:
C07D 471/08
US Classification:
544127, 546121, 544362
Abstract:
Aryl substituted diazabicyclooctanes (DBO) compounds that inhibit β-lactamases of class A, class C or class D and potentiate β-lactam antibiotics are disclosed. In particular, this disclosure provides DBO compounds that, when used in the disclosed Synergy MIC Assay with a β-lactam antibiotic at a fixed concentration have an MIC of 8 μg/mL or less against one or more isogenic β-lactamase expressing bacterial strains.
1,3,4-Oxadiazole And 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
Yong He - Bedford MA, US Ning Yin - Lexington MA, US Dylan C. Alexander - Watertown MA, US Jason B. Cross - Acton MA, US Robert Busch - Wakefield MA, US
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
Yong He - Bedford MA, US Ning Yin - Lexington MA, US Dylan C. Alexander - Watertown MA, US Jason B. Cross - Acton MA, US Robert Busch - Wakefield MA, US
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
1,2,4-Oxadiazole And 1,2,4-Thiadiazole Beta-Lactamase Inhibitors
Yong He - Bedford MA, US Ning Yin - Lexington MA, US Dylan C. Alexander - Watertown MA, US Jason B. Cross - Acton MA, US Robert Busch - Wakefield MA, US
International Classification:
C07D 471/08 A61K 31/546 A61K 31/439
US Classification:
514203, 546121, 514300, 514202
Abstract:
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
Name / Title
Company / Classification
Phones & Addresses
Mr. Jason Cross Vice-President
Jim Gauthier Pontiac Buick GMC Auto/Truck Dealers-New & Used
William Jason Massengale (born June 13, 1979) is an American professional wrestler. He is best known by his ring name Jason Cross and for his tenure in ...
2011 to 2000 Family TeacherLilla Fredrick Pilot Middle School Boston, MA 2009 to 2011 Academy CoordinatorGrove Hall Youth Outreach Connection Boston, MA 2007 to 2009 Youth Outreach WorkerPartners Healthcare Boston, MA 2005 to 2007 Human Resource Assistant
Education:
Springfield College School of Human Services Boston, MA Dec 2010 Bachelor of Science in Communication
Stanwood Elementary School New Stanton PA 1987-1991, Wendover Middle School Greensburg PA 1994-1997, Hempfield Area High School Greensburg PA 1997-2001
Community:
Mark Szwast, Carrie Roupe, Amanda Munsky, Christopher Brinker, Sherri Rae
CCIE - CEO (2011) Cross & Cross Industrial Energy - Owner
Education:
Tier One Texas University - Entrepreneurship, Tier One Texas University - Marketing
About:
Cross & Cross enjoys solid CFO relationships nationwide and is listed with Dunn & Bradstreet. Duns Number 95-796-2996. 15 years in business - my customer is my boss.
Tagline:
In the U.S.A. - Cross & Cross Industrial Energy has no price competition. Become Industrial!
Bragging Rights:
Some of our clients have included Fox Television Stations, Frito-Lay, Toshiba, Zenith, Snapple, and Toyota.
Jason Cross
Work:
Legacy Academy - Principal (2011)
Education:
Western State College of Colorado - School Administration and Leadership, Colorado Christian University - Computer Information Systems, Colorado Christian University - Curriculum and Instruction Online Course Development
Jason Cross
Work:
Capgemini - Consultant (2010)
Education:
Goizueta Business School - BBA: Finance, Consulting & Venture Management, Emory University
Jason Cross
Work:
On Site Technology - IT Support Technician (2011) Curriculum Advantage - Network Systems and Adminstrator (2008-2011)
Education:
Pellissippi State Technical Community College - CSIT