Jason C Mcclure

US Patent:

8050731, Nov 1, 2011

Filed:

Nov 16, 2005

Appl. No.:

11/280672

Inventors:

Mark A. Tapsak - San Diego CA, US
Rathbun K. Rhodes - Madison WI, US
Mark C. Shults - Madison WI, US
Jason D. McClure - San Diego CA, US

Assignee:

DexCom, Inc. - San Diego CA

International Classification:

G01N 27/26
A61B 5/00
A61B 5/05

US Classification:

600347, 20440305, 20440311, 20440313, 424424, 21050021, 427 212, 6048911, 600365

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

US Patent:

8053018, Nov 8, 2011

Filed:

Jan 15, 2010

Appl. No.:

12/688737

Inventors:

Mark A. Tapsak - Orangeville PA, US
Rathbun K. Rhodes - Madison WI, US
Mark C. Shults - Madison WI, US
Jason D. McClure - San Diego CA, US

Assignee:

DexCom, Inc. - San Diego CA

International Classification:

G01N 1/28

US Classification:

427 211, 204403, 435 25, 427384, 427 212, 4274301, 4274432

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

US Patent:

20030217966, Nov 27, 2003

Filed:

May 22, 2002

Appl. No.:

10/153356

Inventors:

Mark Tapsak - San Diego CA, US
Rathbun Rhodes - Madison WI, US
Mark Shults - Madison WI, US
Jason McClure - San Diego CA, US

Assignee:

Dexcom, Inc. - San Diego CA

International Classification:

A61K031/00

US Classification:

210/500210, 210/500270, 210/500340

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

US Patent:

20050245795, Nov 3, 2005

Filed:

May 3, 2004

Appl. No.:

10/838909

Inventors:

Paul Goode - Murrieta CA, US
Arnold Holmquist - San Diego CA, US
Mark Tapsak - San Diego CA, US
Mark Shults - Madison WI, US
Victoria Carr-Brendel - Pleasanton CA, US
James Brauker - San Diego CA, US
Paul Neale - San Diego CA, US
Jason McClure - San Diego CA, US
Mark Brister - Encinitas CA, US
Peter Simpson - Del Mar CA, US
Rathbun Rhodes - Madison WI, US

Assignee:

DexCom, Inc. - San Diego CA

International Classification:

A61B005/07
A61B005/05

US Classification:

600302000, 128903000

Abstract:

Abstract of the DisclosureAn implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.

US Patent:

20060068208, Mar 30, 2006

Filed:

Nov 16, 2005

Appl. No.:

11/280102

Inventors:

Mark Tapsak - San Diego CA, US
Rathbun Rhodes - Madison WI, US
Mark Shults - Madison WI, US
Jason McClure - San Diego CA, US

International Classification:

B32B 27/40

US Classification:

428423100, 525296000, 525420000

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

US Patent:

20100041971, Feb 18, 2010

Filed:

Oct 29, 2009

Appl. No.:

12/608872

Inventors:

Arnold L. Holmquist - San Diego CA, US
Mark A. Tapsak - Orangeville PA, US
Mark Shults - Madison WI, US
Victoria Carr-Brendel - San Diego CA, US
James H. Brauker - Cement City MI, US
Paul V. Neale - San Diego CA, US
Jason D. McClure - San Diego CA, US
Mark Brister - Encinitas CA, US
Peter C. Simpson - Encinitas CA, US
Rathbun K. Rhodes - Madison WI, US

Assignee:

DexCom, Inc. - San Diego CA

International Classification:

A61B 5/1468
H01R 43/00

US Classification:

600345, 29825

Abstract:

An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.

US Patent:

20120040101, Feb 16, 2012

Filed:

Oct 27, 2011

Appl. No.:

13/283397

Inventors:

Mark A. Tapsak - Orangeville PA, US
Rathbun K. Rhodes - Madison WI, US
Mark C. Shults - Madison WI, US
Jason D. McClure - San Diego CA, US

Assignee:

DexCom, Inc. - San Diego CA

International Classification:

B05D 7/00
B05D 3/00
C09D 175/08
B05D 5/00

US Classification:

4273855, 524500

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

US Patent:

20130030273, Jan 31, 2013

Filed:

Sep 28, 2012

Appl. No.:

13/631780

Inventors:

Rathbun K. Rhodes - Madison WI, US
Mark C. Shults - Madison WI, US
Jason D. McClure - San Diego CA, US

Assignee:

DexCom, Inc. - San Jose CA

International Classification:

A61B 5/145
B05D 5/00

US Classification:

600365, 427 212

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.