Jason M Stein

US Patent:

20090263345, Oct 22, 2009

Filed:

Feb 27, 2009

Appl. No.:

12/380463

Inventors:

Joseph A. Capriotti - New York NY, US
Bo Liang - East Brunswick NJ, US
C. Michael Samson - New York NY, US
Jason Stein - New York NY, US
Michael Weiser - New York NY, US

Assignee:

Foresight Biotherapeutics, Inc. - New York NY

International Classification:

A61K 31/79
A61P 27/16

US Classification:

424 7807

Abstract:

Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.

US Patent:

20120027716, Feb 2, 2012

Filed:

Jun 10, 2009

Appl. No.:

12/997374

Inventors:

Jason Stein - New York NY, US
Bo Liang - East Brunswick NJ, US
C. Michael Samson - New York NY, US
Joseph A. Capriotti - Las Palmas, ES
Michael Weiser - New York NY, US
Mark B. Abelson - Andover MA, US

Assignee:

Foresight Biotherapeutics, Inc. - New York NY

International Classification:

A01N 43/36
A01P 1/00
A61P 27/02

US Classification:

424 7832

Abstract:

The invention includes a preserved ophthalmic preparation comprising povidone-iodine (PVP-I) at a concentration sufficient to preserve the ophthalmic preparation, and at least one member selected from the group consisting of a steroidal anti-inflammatory compound, a non-steroidal anti-inflammatory compound, an antibacterial compound, an anti-allergy compound, and an anti-glaucoma compound. The invention also includes adding PVP-I to an ophthalmic composition in order to preserve the composition, wherein the PVP-I is added at a concentration sufficient to preserve the composition.

US Patent:

20050032807, Feb 10, 2005

Filed:

Aug 6, 2003

Appl. No.:

10/634811

Inventors:

Lindsay Rosenwald - Lawrence NY, US
Michael Weiser - New York NY, US
Jason Stein - New York NY, US
Jeff Serbin - New York NY, US

International Classification:

A61K031/525

US Classification:

514251000

Abstract:

The present invention relates to pharmaceutically active ornithine compounds, particularly to pharmaceutically acceptable ammonium salts of N-acyl derivatives of N(4-amino-4-deoxypteroyl)-L-ornithine compounds; and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such ammonium salts. The ammonium salts provided by the invention exhibit superior chemical stability than corresponding acidic N-acyl derivatives of N-acyl derivatives of N(4-amino-4-deoxypteroyl)-L-ornithine compounds.

US Patent:

20210322372, Oct 21, 2021

Filed:

Apr 12, 2021

Appl. No.:

17/228054

Inventors:

- New York NY, US
Jason STEIN - New York NY, US
Donald PICKER - Jersey City NJ, US

Assignee:

Cortice Biosciences, Inc. - New York NY

International Classification:

A61K 31/357
A61P 25/28

Abstract:

The present disclosure is directed, at least in part, to disease-modifying treatments for neurodegenerative disorders. In one embodiment, a method of delaying worsening of one or more symptoms and/or progression of a neurodegenerative disorder is provided. In one embodiment, a method of treating or ameliorating one or more symptoms of a neurodegenerative disorder is provided. In one embodiment, the methods of the present invention comprise administering to a subject in need thereof, a compound having the structure of formula (1a); Formula (1a); and/or a pharmaceutically acceptable salt thereof. In one embodiment, the the compound of (1a) and/or a pharmaceutically acceptable salt thereof is administered in combination with one or more pharmacologically active agents.

US Patent:

20170281592, Oct 5, 2017

Filed:

Jun 15, 2017

Appl. No.:

15/624263

Inventors:

- New York NY, US
Jason STEIN - New York NY, US
Donald PICKER - Jersey City NJ, US

Assignee:

Cortice Biosciences, Inc. - New York NY

International Classification:

A61K 31/357

Abstract:

The present disclosure is directed, at least in part, to disease-modifying treatments for neurodegenerative disorders. In one embodiment, a method of delaying worsening of one or more symptoms and/or progression of a neurodegenerative disorder is provided. In one embodiment, a method of treating or ameliorating one or more symptoms of a neurodegenerative disorder is provided. In one embodiment, the methods of the present invention comprise administering to a subject in need thereof, a compound having the structure of Formula (1a); Formula (1a); and/or a pharmaceutically acceptable salt thereof. In one embodiment, the the compound of (1a) and/or a pharmaceutically acceptable salt thereof is administered in combination with one or more pharmacologically active agents.

US Patent:

20160175279, Jun 23, 2016

Filed:

Jul 2, 2014

Appl. No.:

14/902190

Inventors:

- New York NY, US
Jason STEIN - New York NY, US
Donald PICKER - Jersey City NJ, US

Assignee:

Cortice Biosciences, Inc. - New York NY

International Classification:

A61K 31/357

Abstract:

The present disclosure is directed, at least in part, to disease-modifying treatments for neurodegenerative disorders. In one embodiment, a method of delaying worsening of one or more symptoms and/or progression of a neurodegenerative disorder is provided. In one embodiment, a method of treating or ameliorating one or more symptoms of a neurodegenerative disorder is provided. In one embodiment, the methods of the present invention comprise administering to a subject in need thereof, a compound having the structure of Formula ():Formula (); and/or a pharmaceutically acceptable salt thereof. In one embodiment, the the compound of () and/or a pharmaceutically acceptable salt thereof is administered in combination with one or more pharmacologic ally active agents.

US Patent:

20150038473, Feb 5, 2015

Filed:

May 11, 2012

Appl. No.:

14/117086

Inventors:

Jason Stein - New York NY, US
Michael Weiser - New York NY, US
Joseph A. Capriotti - Christiansted VI, US
Bo Liang - East Brunswick NJ, US
C. Michael Samson - New York NY, US

Assignee:

FORESIGHT BIOTHERAPEUTICS, INC. - New York NY

International Classification:

A61K 31/573
A61K 9/00
A61K 31/196
A61K 31/56
A61K 47/34

US Classification:

514171, 514179, 514180, 514567

Abstract:

Disclosed are stable compositions comprising povidone-iodine and a steroid, and methods of making and using such compositions. Also disclosed herein are stable compositions comprising povidone-iodine and an NSAID, and methods of making and using such compositions.