- Rahway NJ, US Nicole Miller Damour - Rainier MD, US Lisa Duong - Lynn MA, US Valdas Jurkauskas - Cambridge MA, US Kristos Adrian Moshos - Belmont MA, US Sanjay Mudur - Woburn MA, US Asli Ovat - Maynard MA, US Joseph Terracciano - Concord MA, US Jason Woertink - Midland MI, US
International Classification:
A61K 31/546 A61K 31/431 A61K 47/10 C07D 501/57
Abstract:
Ceftolozane Sulfate is a cephalosporin antibacterial agent. Novel, stable, solid forms of the pharmaceutically acceptable sulfate salt of ceftolozane have been isolated via lyophilization. Characterization and identification of these solid forms by XRPD and Raman IR, as well as methods for their preparation and use in pharmaceutical compositions, are described.
- Lexington MA, US Nicole Miller Damour - Belmont MA, US Lisa Duong - Lynn MA, US You Seok Hwang - Windham NH, US Kristos Adrian Moshos - Belmont MA, US Sanjay Mudur - Woburn MA, US Asli Ovat - Maynard MA, US Joseph Terracciano - Concord MA, US Jason Woertink - Sudbury MA, US
Assignee:
CALIXA THERAPEUTICS, INC. - Lexington MA
International Classification:
A61K 31/546 A61K 31/431
US Classification:
514192, 544 47, 514207
Abstract:
Novel solid forms of ceftolozane are described, as well as methods for the preparation and use of these solid forms.
Cubist Pharmaceuticals Feb 2013 - Apr 2014
Senior Research Associate I
Ontorii Jul 2010 - Mar 2011
Research Specialist
Geron Nov 2008 - Mar 2010
Development Associate Ii
Sunesis Pharmaceuticals Apr 2008 - Jun 2008
Staff Research Associate I
Caltech Mar 2002 - Sep 2003
Research Assistant
Education:
Stanford University 2008
Master of Science, Masters
Stanford University 2003 - 2008
Masters, Chemistry
Occidental College 2001
Bachelors, Bachelor of Arts
Occidental College 1998 - 2001
Bachelors, Chemistry
Skills:
Chemistry Drug Discovery Nmr Organic Chemistry Research Analysis Biotechnology Mass Spectrometry Analytical Chemistry Lc Ms Life Sciences Pharmaceutical Industry
Apr 2011 to 2000 Research Associate (Contract)Ontorii Inc Boston, MA Aug 2010 to Mar 2011 Research Specialist (Contract)Geron Inc Menlo Park, CA Nov 2008 to Mar 2010 Development Associate IISunesis Inc San Francisco, CA Jun 2008 to Jun 2008 Staff Research Associate I (Contract)California Institute Of Technology Pasadena, CA Mar 2002 to Sep 2003 Research AssistantMateria Inc Pasadena, CA May 2001 to Feb 2002 Research ChemistOccidental College Los Angeles, CA Sep 2000 to May 2001 NMR Technician
Education:
Stanford University Stanford, CA 2008 Master of Science in ChemistryOccidental College Los Angeles, CA 2001 Bachelor of Arts in Chemistry
Skills:
Instruments: LC-MS, NMR, GC, HPLC, IR, UV/VIS, Laboratory: Organic synthesis, purification, and structural characterization of compounds Computer Skills: ChemDraw, SciFinder Scholar, ISIS Draw, Excel, E-Notebook