The present invention provides replication competent adenoviral vectors capable of expressing antigens from infectious pathogens, such as influenza virus. The adenoviral vectors can be used to vaccinate subjects against the infectious pathogens. The adenoviral vectors comprise heterologous sequences encoding the antigens. The heterologous sequences can be inserted into various locations in the adenoviral vectors, including in or near specific E3 deletions and/or integrated into the adenoviral hexon coding region. The adenoviral vectors can be derived from any adenoviral serotype, particularly an Ad4 or Ad7 serotype.
Brush Encoding Device For System To Promote Optimum Performance Of Handheld Cosmetic Device
- Paris, FR Ryan RUTLEDGE - Lynnwood WA, US Jeff ALEXANDER - North Bend WA, US
Assignee:
L'OREAL - Paris
International Classification:
A47K 7/04 A46B 15/00 B08B 1/00
Abstract:
A personal care appliance is provided that includes a brushhead for use in skincare; an appliance body having a motor assembly for oscillating the brushhead, wherein the brushhead or a portion of the motor assembly that is configured to oscillate includes a marking; and a brush encoder configured to detect the marking, and determine the oscillation of the brushhead.
- San Diego CA, US Jeff ALEXANDER - San Diego CA, US
International Classification:
C12N 15/86 C12N 7/00 A61K 39/145
US Classification:
4241861, 4242331
Abstract:
The present invention provides replication competent adenoviral vectors capable of expressing antigens from infectious pathogens, such as influenza virus. The adenoviral vectors can be used to vaccinate subjects against the infectious pathogens. The adenoviral vectors comprise heterologous sequences encoding the antigens. The heterologous sequences can be inserted into various locations in the adenoviral vectors, including in or near specific E3 deletions and/or integrated into the adenoviral hexon coding region. The adenoviral vectors can be derived from any adenoviral serotype, particularly an Ad4 or Ad7 serotype.
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Jeff Alexander
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Jeff Alexander
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Jeff Alexander
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Jeff Alexander
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