Jeffrey R Capadona

US Patent:

8344060, Jan 1, 2013

Filed:

Apr 8, 2009

Appl. No.:

12/384729

Inventors:

Christoph Weder - Shaker Heights OH, US
Stuart J. Rowan - Cleveland Heights OH, US
Jeffrey R. Capadona - North Ridgeville OH, US
Dustin J. Tyler - Highland Heights OH, US
Kadhiravan Shanmuganathan - Cleveland OH, US
Otto van den Berg - Leuven, BE

Assignee:

Case Western Reserve University - Cleveland OH
The United States of America as Represented by the Department of Veterans Affairs - Washington DC

International Classification:

C08K 3/04
C08K 3/34

US Classification:

524496, 977956, 977753, 977762, 977773, 977778, 977775

Abstract:

Polymer nanocomposites exhibit a reversible change in stiffness and strength in response to a stimulus. The polymer nanocomposites include a matrix polymer with a comparably low modulus and strength and nanoparticles that have a comparably high modulus and strength. The particle-particle interactions are switched by the stimulus, to change the overall material's mechanical properties. In a preferred embodiment, a chemical regulator is used to facilitate changes of the mechanical properties. Methods for inducing modulus changes in polymer nanocomposites are also disclosed.

US Patent:

20080242765, Oct 2, 2008

Filed:

Mar 26, 2008

Appl. No.:

12/079264

Inventors:

Christoph Weder - Shaker Heights OH, US
Jeffrey Capadona - North Ridgeville OH, US
Otto van den Berg - Grembergen, BE

Assignee:

CASE WESTERN RESERVE UNIVERSITY - CLEVELAND OH

International Classification:

C08K 7/00

US Classification:

523201

Abstract:

Polymer nanocomposites, nanoparticle-containing organogels utilized in forming the polymer nanocomposites, and methods for forming the polymer nanocomposites and nanoparticle-containing organogels are disclosed. Relatively simple and versatile methods are utilized to form the polymer nanocomposites. The process is based on the format of a three-dimensional network of well-individualized nanoparticles, such nanofibers through gelation thereof with an appropriate non-polymeric solvent. The nanoparticle-containing organogel is subsequently filled with a solution of a desired matrix polymer, the composite is dried and compacted to create the polymer nanocomposite. Polymer nanocomposites can be prepared which exhibit dramatic changes in mechanical properties, such as increased shear modulus, when compared to the neat polymer.

US Patent:

20130165554, Jun 27, 2013

Filed:

Dec 18, 2012

Appl. No.:

13/718027

Inventors:

Christoph Weder - Shaker Heights OH, US
Stuart J. Rowan - Cleveland Heights OH, US
Jeffrey R. Capadona - North Ridgeville OH, US
Dustin J. Tyler - Highland Heights OH, US
Kadhiravan Shanmuganathan - Cleveland OH, US
Otto van den Berg - Grembergen, BE

Assignee:

The United States Government as Represented by the Department of Veterans Affairs - Washington DC
CASE WESTERN RESERVE UNIVERSITY - Cleveland OH

International Classification:

C08L 1/00

US Classification:

524 35

Abstract:

Polymer nanocomposites exhibit a reversible change in stiffness and strength in response to a stimulus. The polymer nanocomposites include a matrix polymer with a comparably low modulus and strength and nanoparticles that have a comparably high modulus and strength. The particle-particle interactions are switched by the stimulus, to change the overall material's mechanical properties. In a preferred embodiment, a chemical regulator Is used to facilitate changes of the mechanical properties. Methods for inducing modulus changes in polymer nanocomposites are also disclosed.

US Patent:

20200138312, May 7, 2020

Filed:

May 16, 2018

Appl. No.:

16/613255

Inventors:

- Cleveland OH, US
Pamela Vandevord - Cleveland OH, US
Jeffrey R. Capadona - Cleveland OH, US

International Classification:

A61B 5/04

Abstract:

The present disclosure relates to an implantable medical device with surface modifications to add additional surface area to the surface of the implantable device. The surface modifications create a rough, nanopatterned surface of the implantable medical device. The rough, nanopatterned surface can mimic a natural environment of an area of the subject's body, thereby reducing an immune foreign body response.