Jeffrey S Ellis

US Patent:

20230049247, Feb 16, 2023

Filed:

Jul 23, 2022

Appl. No.:

17/871907

Inventors:

- Columbus OH, US
Kavitha Dasu - Powell OH, US
Russel R. Sirabian - Columbus OH, US
Amy Dindal - Rockland MA, US
Jeffrey Ellis - Columbus OH, US
Amy Heintz - Dublin OH, US
Dan Garbark - Columbus OH, US
Nathan Bryant - Columbus OH, US
John Tallarico - Columbus OH, US
Joseph Casciano - Columbus OH, US
Slawomir Winecki - Columbus OH, US
David Holley - Columbus OH, US
Joshua James - Columbus OH, US
Keith Brown - Solon OH, US
Doug Hendry - Columbus OH, US
Darwin Argumedo - Columbus OH, US
Aaron Frank - Dublin OH, US
Christopher Gordon Scheitlin - Columbus OH, US
Michael M. Miller - Worthington OH, US

International Classification:

C02F 1/44
C02F 1/04
C02F 1/72

Abstract:

Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.

US Patent:

20230020138, Jan 19, 2023

Filed:

Sep 15, 2022

Appl. No.:

17/945486

Inventors:

- Columbus OH, US
Gaurav Sharma - Columbus OH, US
Andrew Sweeney - Columbus OH, US
Amy M. Heintz - Dublin OH, US
Stephanie Kute - Columbus OH, US
Nicholas Annetta - Columbus OH, US
Thomas D. Haubert - Columbus OH, US
Steven M. Risser - Reynoldsburg OH, US
Jeffrey Friend - Columbus OH, US
John Bartholomew - Columbus OH, US
Rachel Thurston - Columbus OH, US
Alexander C. Morrow - Gahanna OH, US
George Brand - Columbus OH, US
Jeffrey Ellis - Columbus OH, US
Matthew Mowrer - Columbus OH, US
Raymond Zaborski - Columbus OH, US

International Classification:

A61N 1/05
A61N 1/04
A61B 5/00
A61B 5/11
A61B 5/291
A61B 5/375
A61B 5/389

Abstract:

The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

US Patent:

20210112627, Apr 15, 2021

Filed:

Sep 23, 2020

Appl. No.:

17/030329

Inventors:

- Columbus OH, US
Kurt Bosworth - Woodstock OH, US
Kevin Yugulis - Columbus OH, US
Amy M. Heintz - Dublin OH, US
Jeffrey L. Ellis - Columbus OH, US

International Classification:

H05B 3/00
H05B 3/03

Abstract:

A device is described in which the shape of a resistive heater material is configured to provide rapid and strong heating of a small area. The resistive heating material is heated unevenly while efficiently using power.

US Patent:

20210038816, Feb 11, 2021

Filed:

Aug 31, 2018

Appl. No.:

16/645320

Inventors:

- Indianapolis IN, US
Anthony David DUONG - Columbus OH, US
Jeffrey LeClair ELLIS - Columbus OH, US
Michael W. HARRISON - Sharon MA, US
Lampros C. KOURTIS - Cambridge MA, US
Rhea SIRKAR - Brighton MA, US
John Paul TALLARICO - Powell OH, US

International Classification:

A61M 5/20
A61M 5/19

Abstract:

A chemical reaction system is disclosed for use in a device for delivering a therapeutic fluid comprising a liquid base and a polymeric acid. A reaction rate of the chemical reaction system is capable of being adjusted by adjusting at least one of surface area-to-volume ratio, acid concentration, and cross-linking of the polymeric acid.

US Patent:

20200407241, Dec 31, 2020

Filed:

Jun 29, 2020

Appl. No.:

16/916085

Inventors:

- Columbus OH, US
Kavitha Dasu - Powell OH, US
Russel R. Sirabian - Columbus OH, US
Amy Dindal - Rockland MA, US
Jeffrey Ellis - Columbus OH, US
Amy Heintz - Dublin OH, US
Dan Garbark - Columbus OH, US
Nathan Bryant - Columbus OH, US
John Tallarico - Columbus OH, US
Joseph Casciano - Columbus OH, US
Slawomir Winecki - Columbus OH, US
David Holley - Columbus OH, US
Joshua James - Columbus OH, US
Keith Brown - Solon OH, US
Doug Hendry - Columbus OH, US
Darwin Argumedo - Columbus OH, US
Aaron Frank - Dublin OH, US

International Classification:

C02F 1/44
C02F 1/04
C02F 1/72

Abstract:

Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.

US Patent:

20200276438, Sep 3, 2020

Filed:

May 19, 2020

Appl. No.:

16/877554

Inventors:

- Columbus OH, US
Gaurav Sharma - Columbus OH, US
Andrew Sweeney - Columbus OH, US
Amy M. Heintz - Dublin OH, US
Stephanie Kute - Columbus OH, US
Nicholas Annetta - Columbus OH, US
Thomas D. Haubert - Columbus OH, US
Steven M. Risser - Reynoldsburg OH, US
Jeffrey Friend - Columbus OH, US
John Bartholomew - Columbus OH, US
Rachel Thurston - Columbus OH, US
C. Alexander Morrow - Gahanna OH, US
George Brand - Columbus OH, US
Jeffrey Ellis - Columbus OH, US
Matthew Mowrer - Columbus OH, US
Raymond Zaborski - Columbus OH, US

International Classification:

A61N 1/05
A61B 5/0488
A61N 1/04
A61B 5/00
A61B 5/0478
A61B 5/0482
A61B 5/11

Abstract:

The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

US Patent:

20200054831, Feb 20, 2020

Filed:

Oct 22, 2019

Appl. No.:

16/659592

Inventors:

- Columbus OH, US
Steven M. Risser - Reynoldsburg OH, US
Amy M. Heintz - Dublin OH, US
Jeffrey L. Ellis - Gahanna OH, US
John D. Clay - Gahanna OH, US
Timothy M. Blum - Columbus OH, US

International Classification:

A61M 5/20
A61M 5/28
A61M 5/19

Abstract:

Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.

US Patent:

20200030537, Jan 30, 2020

Filed:

Feb 9, 2018

Appl. No.:

16/484676

Inventors:

- Indianapolis IN, US
Corrie Jo BENNISON - Lewis Center OH, US
Robert Jonathan CAIN - Lewis Center OH, US
Michael Funk CHIAPPETTA - Greenwood IN, US
Jeffrey LeClair ELLIS - Columbus OH, US
David Arthur HOLLEY - Lancaster OH, US
Mark LAFEVER - Indianapolis IN, US
Beverly Ann PIATT - Columbus OH, US
John Paul TALLARICO - Powell OH, US

International Classification:

A61M 5/20

Abstract:

Processes and devices are disclosed for parenteral delivery of therapeutic fluids, in particular high-viscosity therapeutic fluids (e.g., protein therapeutics), by a chemical reaction that generates a gas. The device may include a first actuation chamber containing a first reagent, a second reaction chamber containing a second reagent, and a third therapeutic fluid chamber containing the therapeutic fluid. In a loaded configuration, a plunger separates the first chamber from the second chamber. In a delivery configuration, the plunger allows the first reagent from the first chamber to communicate and react with the second reagent from the second chamber. The generated gas acts upon a plunger to deliver the therapeutic fluid from the third chamber.