Jen-Kuei Liu

US Patent:

20030165540, Sep 4, 2003

Filed:

May 4, 2001

Appl. No.:

09/849729

Inventors:

Jen-Kuei Liu - Palo Alto CA, US
Samantha Lewis - San Francisco CA, US
Hans-Georg Batz - Tutzing, DE
Latha Ramaswamy - San Jose CA, US
Roy Bohenzky - Mountain View CA, US
Yu-Huei Lin - Sunnyvale CA, US
Janine Montiel - Fremont CA, US
Benjamin Chen - Fremont CA, US

International Classification:

A61K039/29
C12Q001/70
C07H021/04
C12N007/00

US Classification:

424/225100, 435/005000, 536/023720, 435/235100

Abstract:

The invention relates to a new virus, designated H101.c33 or Sentinel Virus II (SVII). Isolated SVII viruses, polynucleotides and proteins from SVII viruses, and antibodies which bind SVII virus and SVII viral proteins are provided. The polynucleotides, proteins, and antibodies of the invention may be used to detect SVII virus or infection by SVII virus in a susceptible individual. Additionally, polynucleotides of the invention may be inserted into recombinant expression vectors for recombinant production of viral proteins.

US Patent:

20030198947, Oct 23, 2003

Filed:

Jun 3, 2003

Appl. No.:

10/453264

Inventors:

Jen-Kuei Liu - Palo Alto CA, US
Roy Bohenzky - Mountain View CA, US
Yu-Huei Lin - Sunnyvale CA, US
Benjamin Chen - Fremont CA, US

International Classification:

C12Q001/70
G01N033/53
C07H021/02
C12N007/00
C12N015/00
C12N015/70
C12N005/16
C07K001/00
C07K014/00
C07K017/00
C12Q001/68
A61K039/29
C12N007/02

US Classification:

435/005000, 424/189100, 435/235100, 435/239000, 435/320100, 435/326000, 435/339000, 435/006000, 435/007100, 530/350000, 536/023100, 536/023720

Abstract:

The invention relates to a new group of viruses, designated SVI. Isolated SVI viruses, polynucleotides and proteins from SVI viruses, and antibodies which bind SVI virus and SVI viral proteins are provided. The polynucleotides, proteins, and antibodies of the invention may be used to detect SVI virus or infection by SVI virus in a susceptible individual. Additionally, polynucleotides of the invention may be inserted into recombinant expression vectors recombinant production of viral proteins.

US Patent:

20100273143, Oct 28, 2010

Filed:

Mar 25, 2010

Appl. No.:

12/731806

Inventors:

Michael Brewer - Boulder CO, US
Jen-Kuei Liu - Palo Alto CA, US
Craig Cummings - Pacifica CA, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C12Q 1/70
C07H 21/04
C12Q 1/68

US Classification:

435 5, 536 237, 435 6

Abstract:

The present teachings generally relate to methods and kits incorporating a discriminating positive control for determining whether a particular microorganism or group of microorganisms are present in a sample, for example but not limited to a food, environmental, agricultural, biopharmaceutical, pharmaceutical, or water sample. According to certain methods, at least part of a starting material, for example but not limited to, a food, environmental, agricultural, biopharmaceutical, pharmaceutical, or water sample can be combined with a culture medium and incubated under conditions suitable for microbial growth followed by extracting microorganism and added control nucleic acids for analysis. The extracted nucleic acids are amplified and the amplified nucleic acids are detected, directly or indirectly, and the fidelity of the methods and the presence or absence of the corresponding microorganism is determined because the discriminating positive control provides both confirmatory results for the methods used but eliminates false positive results.

US Patent:

20110111403, May 12, 2011

Filed:

Oct 29, 2010

Appl. No.:

12/916420

Inventors:

Pius Brzoska - Woodside CA, US
Somaya Bit - San Ramon CA, US
Jen-Kuei Liu - Palo Alto CA, US
Robert Tebbs - Livermore CA, US
Manohar Furtado - San Ramon CA, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C12Q 1/68
C07H 21/04

US Classification:

435 6, 536 2433

Abstract:

Disclosed is a multi-primer amplification assay, method and kits for detecting species and closely related species utilizing a plurality of oligonucleotide primers in contact with a sample in a single vessel and detecting the amplification product, wherein the presence of an amplification product indicates in the sample.

US Patent:

20010034018, Oct 25, 2001

Filed:

Dec 8, 2000

Appl. No.:

09/732665

Inventors:

Jen-Kuei Liu - Palo Alto CA, US
Roy Bohenzky - Mountain View CA, US
Yu-Huei Lin - Sunnyvale CA, US
Benjamin Chen - Fremont CA, US

International Classification:

C12Q001/70
C07H021/04
A61K039/29
C12N007/00
G01N033/53
C07K001/00

US Classification:

435/005000, 536/023720, 424/189100, 435/006000, 435/007100, 435/235100, 435/239000, 435/326000, 435/339000, 435/320100, 530/350000, 536/023100

Abstract:

The invention relates to a new group of viruses, designated SVI. Isolated SVI viruses, polynucleotides and proteins from SVI viruses, and antibodies which bind SVI virus and SVI viral proteins are provided. The polynucleotides, proteins, and antibodies of the invention may be used to detect SVI virus or infection by SVI virus in a susceptible individual. Additionally, polynucleotides of the invention may be inserted into recombinant expression vectors recombinant production of viral proteins.

US Patent:

20140378330, Dec 25, 2014

Filed:

Jun 25, 2014

Appl. No.:

14/314985

Inventors:

- Carlsbad CA, US
Pius Brzoska - Woodside CA, US
Somaya Bit - San Ramon CA, US
Jen-Kuei Liu - Palo Alto CA, US
Robert Tebbs - Austin TX, US
Manohar Furtado - San Ramon CA, US

International Classification:

C12Q 1/68

US Classification:

506 9, 506 23, 506 16

Abstract:

Disclosed is a multi-primer amplification assay, method and kits for detecting species and closely related species utilizing a plurality of oligonucleotide primers in contact with a sample in a single vessel and detecting the amplification product, wherein the presence of an amplification product indicates in the sample.