Michael John Alberti - Durham NC, US Stanley D. Chamberlain - Durham NC, US Mui Cheung - Durham NC, US Kristjan Gudmundsson - Durham NC, US Philip Anthony Harris - Durham NC, US Brian A. Johns - Durham NC, US David Kendall Jung - Durham NC, US Michael Robert Peel - Durham NC, US Jennifer Badiang Stanford - Durham NC, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07D 403/04 A61K 31/505
US Classification:
514256, 514269, 514275, 544333
Abstract:
The present invention provides compounds of formula (I): wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.
Pyrazolopyridines, Process For Their Preparation And Use As Therapeutic Compounds
Michael John Alberti - Durham NC, US Stanley D. Chamberlain - Durham NC, US Mui Cheung - Durham NC, US Kristjan Gudmundsson - Durham NC, US Philip Anthony Harris - Durham NC, US Brian A. Johns - Durham NC, US David Kendall Jung - Durham NC, US Michael Robert Peel - Durham NC, US Jennifer Badiang Stanford - Durham NC, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07D 471/04 A61K 31/4162
US Classification:
514300, 546113
Abstract:
The present invention provides compounds of formula (I):.
Robert Carl Andrews - Durham NC Marc Werner Andersen - Raleigh NC Dulce Garrido Bubacz - Cary NC Joseph Howing Chan - Chapel Hill NC David John Cowan - Hillsborough NC Michael David Gaul - Apex NC Daryl Lynn McDougald - Durham NC David Lee Musso - Raleigh NC Michael Howard Rabinowitz - Durham NC Jennifer Badiang Stanford - Cary NC Robert William Wiethe - Durham NC
Assignee:
Glaxo Wellcome Inc. - Research Triangle Park NC
International Classification:
C07D40912 C07D21374 A61K 314436 A61K 314409
US Classification:
514336
Abstract:
A family of compounds having the general structural formula ##STR1## where W is a reverse hydroxamic acid group, and R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4, R. sub. 5 and R. sub. 6 are as described in the specification, or a pharmaceutically acceptable salt, solvate, biohydrolyzable ester, biohydrolyzable amide, affinity reagent, or prodrug thereof.
Robert Carl Andrews - Durham NC Marc Werner Andersen - Raleigh NC Dulce Garrido Bubacz - Cary NC Joseph Howing Chan - Chapel Hill NC David John Cowan - Hillsborough NC Michael David Gaul - Apex NC Daryl Lynn McDougald - Durham NC David Lee Musso - Raleigh NC Michael Howard Rabinowitz - Durham NC Jennifer Badiang Stanford - Cary NC Robert William Wiethe - Durham NC
A family of compounds having the general structural formula ##STR1## where W is a reverse hydroxamic acid group, and R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4, R. sub. 5 and R. sub. 6 are as described in the specification, or a pharmaceutically acceptable salt, solvate, biohydrolyzable ester, biohydrolyzable amide, affinity reagent, or prodrug thereof.