Jenny Yuanmei Chen Louie

US Patent:

56139586, Mar 25, 1997

Filed:

Jun 6, 1995

Appl. No.:

8/469178

Inventors:

Frank Kochinke - San Jose CA
William R. Pfister - Union City CA
Jenny Louie - Fremont CA
Dan Arenson - Escondido CA

Assignee:

PP Holdings Inc. - Menlo Park CA

International Classification:

A61F 1302

US Classification:

604307

Abstract:

A transdermal delivery system for the modulated administration of drugs is described. The drug delivery device comprises a backing; a drug reservoir containing the drug, a plasticizer-type enhancer, a solvent-type enhancer, and optionally, a gelling agent; a non-rate-controlling membrane; and an adhesive layer containing a plasticizer-type enhancer. This drug delivery system is particularly useful for the administration of tolerance-inducing drugs, for example, vasodilators, such as isosorbide dinitrate.

US Patent:

48570800, Aug 15, 1989

Filed:

Dec 2, 1987

Appl. No.:

7/127946

Inventors:

Richard W. Baker - Palo Alto CA
Jenny Louie - Fremont CA
Peter H. Pfromm - Palo Alto CA
Johannes G. Wijmans - Menlo Park CA

Assignee:

Membrane Technology & Research, Inc. - Menlo Park CA

International Classification:

B01D 5322

US Classification:

55 16

Abstract:

An ultrathin, high-flux composite membrane for use in gas separation. The membrane comprises a metal layer, typically 500. ANG. or less thick on a microporous support. The support may be as asymmetric Loeb-Sourirajan type membrane or a two-layer composite of a microporous substrate with a very thin sealing layer. The support gives mechanical strength to the membrane but does not contribute significantly to the selectivity. Optionally the metal layer may be overcoated with a second polymeric sealing layer to plug any defects and to protect the fragile surface from mechanical damage. The membrane is particularly useful in the purfication of hydrogen.