Douglas P. GREINER - Fremont CA, US Jeremy STUART - Charlotte NC, US Meng C. TAING - Hayward CA, US Steven M. MENCHEN - Fremont CA, US
Assignee:
APPLIED BIOSYSTEMS INC. - Foster City CA
International Classification:
C40B 20/04 C40B 50/18 C40B 40/04
US Classification:
506 4, 506 32, 506 15
Abstract:
Methods of modifying a nucleophilic surface of a support are described. The methods involve reacting a multifunctional electrophilic reagent with nucleophilic groups on the surface of the support. The resulting electrophilic surface can be used for the covalent attachment of particles (e.g. beads) having nucleophilic functional groups. For example, nucleic acid templates with nucleophilic (e.g., amine) groups can be attached to a surface of the particles. The nucleophilic groups on the nucleic acid templates can then be used to attach the particles to the modified surface of the support. The resulting support-bound particles can be used to analyze (e.g., sequence) the nucleic acid templates on the particles.
Resumes
Freelance Designer/Animator/Compositor At Jeremystuart.tv
Co-founder, Vice President at Selah Genomics Inc, Adjunct Professor, Dept. of Biological Sciences at University of South Carolina
Location:
Greenville, South Carolina Area
Industry:
Biotechnology
Work:
Selah Genomics Inc - Clinical Genomics Center at ITOR since Dec 2012
Co-founder, Vice President
University of South Carolina - Columbia, SC since Jan 2013
Adjunct Professor, Dept. of Biological Sciences
Life Technologies Jan 2010 - Apr 2012
Sr. Scientific Project Coordinator
Life Technologies - Charlotte, NC 2009 - 2010
Staff Scientist, Field Applications
Agencourt Personal Genomics (Acquired by Applied Biosystems) - Beverly, MA 2006 - Dec 2008
Staff Scientist
St. Patrick's High School Quebec City Kuwait 1991-1995
Community:
Samantha Kelly, Marie Desrosiers, Stephane Desrosiers, Kirby Anderon, Carlos Fairfield, Karina Paquet, Stephanie Oshea, Carl Manning, Monica Stark, Paul Forand