Ji An Wang

US Patent:

7138420, Nov 21, 2006

Filed:

Aug 1, 2003

Appl. No.:

10/632888

Inventors:

Joerg Martin Bentzien - White Plains NY, US
Brian Nicholas Cook - Danbury CT, US
Charles Cywin - Bethel CT, US
Roman Wolfgang Fleck - Greenwich CT, US
Ho Yin Lo - Bethel CT, US
Peter Allen Nemoto - Southbury CT, US
Steven S. Pullen - Danbury CT, US
Gregory Paul Roth - Woodstock CT, US
Roger John Snow - Danbury CT, US
Hidenori Takahashi - LaGrangeville NY, US
Ji Wang - Danbury CT, US
Kevin J. Moriarty - East Norriton PA, US
Lei Qiao - Downingtown PA, US
Michael Winters - Morgantown PA, US

Assignee:

Boehringer Ingelheim Pharmaceuticals Inc. - Ridgefield CT

International Classification:

A61K 31/4184
C07D 235/30

US Classification:

514388, 5483047, 5483074, 548248, 5462734, 544121, 544132, 544370, 514378, 514338, 5142345, 51425406

Abstract:

Disclosed are substituted benzimidazole compounds of formula (I):.

US Patent:

8212040, Jul 3, 2012

Filed:

Apr 25, 2006

Appl. No.:

11/410408

Inventors:

Younes Bekkali - Danbury CT, US
Rajashehar Betageri - Bethel CT, US
Mario G. Cardozo - San Francisco CA, US
Thomas A. Gilmore - Salem MA, US
Christian Hanke Justus Joachim Harcken - New Milford CT, US
Thomas Martin Kirrane - Danbury CT, US
Daniel Kuzmich - Danbury CT, US
John Robert Proudfoot - Newtown CT, US
Doris Riether - New York NY, US
Hidenori Takahashi - LaGrangeville NY, US
David S. Thomson - Ridgefield CT, US
Ji Wang - Amherst MA, US
Renee M. Zindell - New Milford CT, US
Hossein Razavi - Danbury CT, US

Assignee:

Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT

International Classification:

C07D 471/02
A61K 31/44

US Classification:

546113, 514300

Abstract:

Compounds of Formula (IA).

US Patent:

20050209284, Sep 22, 2005

Filed:

Feb 9, 2005

Appl. No.:

11/055798

Inventors:

Joerg Bentzien - White Plains NY, US
Brian Cook - Danbury CT, US
Xiang Li - New Milford CT, US
Ho Lo - Bethel CT, US
Chuk Man - Ridgefield CT, US
Ingo Mugge - New Haven CT, US
Peter Nemoto - Southbury CT, US
Steven Pullen - Danbury CT, US
Doris Riether - New York NY, US
Gregory Roth - Woodstock CT, US
Fariba Soleymanzadeh - Brewster NY, US
Hidenori Takahashi - LaGrangeville NY, US
Ji Wang - Danbury CT, US
Andre White - Newtown CT, US
Renee Zindell - New Milford CT, US

Assignee:

Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT

International Classification:

A61K031/4439
A61K031/427
A61K031/422
C07D417/02
C07D413/02
C07D043/02
A61K031/4184

US Classification:

514338000, 514365000, 514374000, 514394000, 546273400, 548181000, 546215000, 548305100, 548307400

Abstract:

Disclosed are compounds of formula(I): wherein Ar, Ar, R, R, R, Rand Xare defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.

US Patent:

20100190773, Jul 29, 2010

Filed:

Mar 19, 2010

Appl. No.:

12/727570

Inventors:

Asitha ABEYWARDANE - Danbury CT, US
Craig Andrew MILLER - Mt. Vernon NY, US
Tina Marie MORWICK - New Milford CT, US
Neil MOSS - Ridgefield CT, US
Matthew Russell NETHERTON - Danbury CT, US
Roger John SNOW - Danbury CT, US
Ji WANG - Amherst MA, US
Jiang-Ping WU - Danbury CT, US
Zhaoming XIONG - Brookfield CT, US

Assignee:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH - Ingelheim

International Classification:

A61K 31/55
C07D 471/04
A61K 31/437
C07D 401/12
A61K 31/4439
C07D 487/04
A61P 3/10
A61P 1/00
A61P 19/02
A61P 25/28
A61P 9/04
A61P 11/06

US Classification:

51421206, 546 86, 514292, 5462767, 514339, 540521

Abstract:

Heterocyclic compounds and analogues thereof and their use as inhibitors of Mitogen-Activated Protein Kinase-Activated Protein kinase-2 (MAPKAP-k2), and also to a method for preventing or treating a disease or disorder that can be treated or prevented by modulating the activity of MAPKAP-K2 in a subject and to pharmaceutical compositions and kits that include these MAPKAP-K2 inhibitors.

US Patent:

20130177273, Jul 11, 2013

Filed:

Jul 12, 2011

Appl. No.:

13/809618

Inventors:

Robert R. Alfano - Bronx NY, US
Michael Etienne - Corning NY, US
Giovanni Milione - New York NY, US
Daniel Aloysius Nolan - Corning NY, US
Henry Sztul - New York NY, US
Ji Wang - Painted Post NY, US

Assignee:

Research Foundation of CUNY on behalf of City College - New York City NY
Corning Incorporated - Corning NY

International Classification:

G02B 6/10
G02B 6/024

US Classification:

385 11, 385126, 385115

Abstract:

A multicore optical component and corresponding methods of converting a linearly or circularly polarized Gaussian beam of light into a radially or azimuthally polarized beam of light are provided. The multicore optical component comprises a plurality of birefringent, polarization maintaining elliptical cores. The elliptical cores collectively define an azimuthally varying distribution of major axes where the orientation of the major axis of a given elliptical core is given by φ=(180/N)*n+θ where n is the core number and θ is any angle greater than 0.