Jian Cao

US Patent:

8551730, Oct 8, 2013

Filed:

Oct 24, 2009

Appl. No.:

12/605325

Inventors:

Oscar Azucena - Santa Cruz CA, US
Joel Kubby - Santa Cruz CA, US
Jian Cao - Stanford CA, US
William Sullivan - Santa Cruz CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N 1/30

US Classification:

435 405

Abstract:

Methods of microscopic imaging of biological tissue using adaptive optics technology to improve the image focus and sharpness. Wavefront measurements are taken by using a novel method of seeding biological tissue by using a fluorescent microsphere as a “guide star” as a natural point-source reference. The current methods are capable of improving the Strehl ratio of modern biological microscopes as much as 15 times.

US Patent:

20230109342, Apr 6, 2023

Filed:

Dec 7, 2022

Appl. No.:

18/062714

Inventors:

- Minneapolis MN, US
Jian Cao - San Jose CA, US
Melissa G.T. Christie - Ham Lake MN, US
Paul J. DeGroot - Minneapolis MN, US
Vladimir P. Nikolski - Blaine MN, US

International Classification:

A61N 1/05
A61N 1/39

Abstract:

Implantable medical electrical leads having electrodes arranged such that a defibrillation coil electrode and a pace/sense electrode(s) are concurrently positioned substantially over the ventricle when implanted as described. The leads include an elongated lead body having a distal portion and a proximal end, a connector at the proximal end of the lead body, a defibrillation electrode located along the distal portion of the lead body, wherein the defibrillation electrode includes a first electrode segment and a second electrode segment proximal to the first electrode segment by a distance. The leads may include at least one pace/sense electrode, which in some instances, is located between the first defibrillation electrode segment and the second defibrillation electrode segment.

US Patent:

20210309616, Oct 7, 2021

Filed:

Jun 21, 2021

Appl. No.:

17/353075

Inventors:

- Albany NY, US
Vincent ALFORD - Sunnyvale CA, US
Anushree KAMATH - Issaquah WA, US
Jian CAO - S. Setauket NY, US
Xiadong REN - Port Jefferson Station NY, US
Nicole SAMPSON - Setauket NY, US
Monaf AWWA - Bel Air MD, US

International Classification:

C07D 239/95
A61P 35/00
C07D 239/56
C07D 403/12

Abstract:

Small molecule inhibitors are claimed that selectively target the hemopexin domain of matrix metalloproteinase 9 (MMP-9) and do not inhibit the protease's catalytic functions. A method of treating cancer in a patient in need thereof with the compounds of the invention is also claimed.

US Patent:

20200038831, Feb 6, 2020

Filed:

Jul 2, 2019

Appl. No.:

16/459689

Inventors:

- Grand Cayman, KY
Filip CRNOGORAC - Redwood City CA, US
Glenn MCGALL - Palo Alto CA, US
Jian CAO - San Mateo CA, US

International Classification:

B01J 19/00
C12Q 1/6837

Abstract:

Provided herein are methods and compositions for the fabrication of patterned arrays, such as nucleotide arrays. The methods and compositions are suited for the transfer and reorientation of array components.

US Patent:

20160369334, Dec 22, 2016

Filed:

Dec 5, 2014

Appl. No.:

15/100919

Inventors:

Wei ZHOU - Saratoga CA, US
Filip CRNOGORAC - Palo Alto CA, US
Glenn MCGALL - Palo Alto CA, US
Jian CAO - Sunnyvale CA, US
- Grand Cayman, KY

International Classification:

C12Q 1/68

Abstract:

Provided herein are methods and compositions for the sequencing of long nucleic acids, such as DNA. The methods and compositions are suited for the spatial labeling and sequencing of long nucleic acid molecules.

US Patent:

20160303534, Oct 20, 2016

Filed:

Dec 5, 2014

Appl. No.:

15/101671

Inventors:

Wei ZHOU - Saratoga CA, US
Filip CRNOGORAC - Palo Alto CA, US
Glenn MCGALL - Palo Alto CA, US
Jian CAO - Sunnyvale CA, US
- Grand Cayman, KY

International Classification:

B01J 19/00

Abstract:

Provided herein are methods and compositions for the fabrication of patterned arrays, such as nucleotide arrays. The methods and compositions are suited for the transfer and reorientation of array components.