Jian S Jin

US Patent:

6514970, Feb 4, 2003

Filed:

Jun 13, 2002

Appl. No.:

10/149805

Inventors:

Dashyant Dhanak - West Chester PA
Steven David Knight - West Chester PA
Gregory Lee Warren - Parkford PA
Jian Jin - West Chester PA
Katherine L. Widdowson - King of Prussia PA
Richard McCulloch Keenan - Malvern PA

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

A61K 315375

US Classification:

5142335, 544141, 544376, 546168, 546202, 5462791, 5483061, 548467, 548518, 548525, 548526, 548527, 548557

Abstract:

The present invention relates to pyrrolidiones, pharmaceutical compostions containing them and their use as antagonist of urotensin II.

US Patent:

6544992, Apr 8, 2003

Filed:

Jun 13, 2002

Appl. No.:

10/149793

Inventors:

Dashyant Dhanak - West Chester PA
Steven David Knight - West Chester PA
Jian Jin - West Chester PA
Richard McCulloch Keenan - Malvern PA

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

A61K 315377

US Classification:

5142355, 544141, 544372, 546208, 546224, 548517, 548518, 548523, 548526, 548557

Abstract:

The present invention relates to pyrrolyl and pyridyl derivatives, pharmaceutical compositions containing them and their use as inhibitors of urotensin II.

US Patent:

7019008, Mar 28, 2006

Filed:

Apr 29, 2005

Appl. No.:

11/119026

Inventors:

Dashyant Dhanak - King of Prussia PA, US
Steven D. Knight - King of Prussia PA, US
Jian Jin - King of Prussia PA, US
Ralph A. Rivero - King of Prussia PA, US
Anthony Sapienza - West Chester PA, US

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

A61K 31/496
C07D 409/14

US Classification:

51425311, 514218, 51425401, 540575, 544364, 544372

Abstract:

A compound of Formula (I): wherein:.

US Patent:

7079241, Jul 18, 2006

Filed:

Apr 5, 2001

Appl. No.:

09/827256

Inventors:

Stephen A. Empedocles - Mountain View CA, US
Andrew R. Watson - Belmont CA, US
Jian Jin - Berkeley CA, US

Assignee:

Invitrogen Corp. - Carlsbad CA

International Classification:

G01J 3/28
G01J 3/00
G01J 3/30
G01J 3/42
G01N 21/29

US Classification:

356326, 356300, 356311, 356317, 356319, 435 4, 436518, 436523, 436524, 422 8205

Abstract:

Devices, systems, kits, and methods for detecting and/or identifying a plurality of spectrally labeled bodies well-suited for performing multiplexed assays. By spectrally labeling the beads with materials which generate identifiable spectra, a plurality of beads may be identified within the fluid. Reading of the beads is facilitated by restraining the beads in arrays, and/or using a focused laser.

US Patent:

7737412, Jun 15, 2010

Filed:

Jul 12, 2005

Appl. No.:

11/571980

Inventors:

Jian Jin - Berkeley CA, US
Robert M. Glaeser - Berkeley CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G21K 5/04
H01J 37/24

US Classification:

250396R, 250309, 250311

Abstract:

A microfabricated electron phase shift element is used for modifying the phase characteristics of an electron beam passing though its center aperture, while not affecting the more divergent portion of an incident beam to selectively provide a ninety-degree phase shift to the unscattered beam in the back focal plan of the objective lens, in order to realize Zernike-type, in-focus phase contrast in an electron microscope. One application of the element is to increase the contrast of an electron microscope for viewing weakly scattering samples while in focus. Typical weakly scattering samples include biological samples such as macromolecules, or perhaps cells. Preliminary experimental images demonstrate that these devices do apply a ninety degree phase shift as expected. Electrostatic calculations have been used to determine that fringing fields in the region of the scattered electron beams will cause a negligible phase shift as long as the ratio of electrode length to the transverse feature-size aperture is about 5:1. Calculations are underway to determine the feasibility of aspect smaller aspect ratios of about 3:1 and about 2:1.

US Patent:

7932247, Apr 26, 2011

Filed:

Nov 15, 2005

Appl. No.:

11/719336

Inventors:

Brian W. Budzik - Collegeville PA, US
Anthony W. J. Cooper - Stevenage, GB
Jian Jin - Collegeville PA, US
Dramane I. Laine - King of Prussia PA, US
Brent W. McCleland - King of Prussia PA, US
Michael R. Palovich - King of Prussia PA, US
Ralph A. Rivero - Collegeville PA, US
Yonghui Wang - Collegeville PA, US
Haibo Xie - King of Prussia PA, US
Chongjie Zhu - King of Prussia PA, US

Assignee:

Glaxo Group Limited - Greenford, Middlesex

International Classification:

A61K 31/496
A61K 31/551
A61K 31/5377
C07D 401/12
C07D 403/12
C07D 409/14
C07D 413/14
C07D 487/10

US Classification:

514218, 5142358, 51425211, 51425301, 51425408, 540575, 544121, 544230, 544357, 544360, 544364, 544373, 544400

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

US Patent:

8283364, Oct 9, 2012

Filed:

Sep 27, 2006

Appl. No.:

12/088465

Inventors:

Brian Budzik - Collegeville PA, US
David Gwyn Cooper - Harlow, GB
Ian Thomson Forbes - Harlow, GB
Vincenzo Garzya - Harlow, GB
Jian Jin - Collegeville PA, US
Dongchuan Shi - Collegeville PA, US
Paul William Smith - Harlow, GB
Graham Walker - Harlow, GB

Assignee:

Glaxo Group Limited - Greenford, Middlesex

International Classification:

A61K 31/454
C07D 405/04

US Classification:

514322, 546199

Abstract:

Compounds of formula (I) and salts are provided:.

US Patent:

8288412, Oct 16, 2012

Filed:

Sep 27, 2006

Appl. No.:

12/088451

Inventors:

Brian Budzik - Collegeville PA, US
David Gwyn Cooper - Harlow, GB
Ian Thomson Forbes - Harlow, GB
Vincenzo Garzya - Harlow, GB
Jian Jin - Collegeville PA, US
Dongchuan Shi - Collegeville PA, US
Paul William Smith - Harlow, GB
Graham Walker - Harlow, GB

Assignee:

Glaxo Group Limited - Greenford, Middlesex

International Classification:

A61K 31/454
C07D 405/04

US Classification:

514322, 546199

Abstract:

Compounds of formula (I) and salts are provided:.