Sherin S. Abdel-Meguid - Exton PA, US Robert E. Babine - Franklin MA, US Hongfeng Deng - Acton MA, US Lei Jin - Wellesley MA, US Jian Lin - Walpole MA, US Scott R. Magee - Somerville MA, US Harold V. Meyers - Weston MA, US Pramod Pandey - Canton MA, US Michael J. Rynkiewicz - Boston MA, US David T. Weaver - Newton MA, US Zihong Gho - Southbury CT, US Thomas D. Bannister - Northborough MA, US
Assignee:
Daiamed, Inc. - Cambridge MA
International Classification:
C07K 14/745 C07K 1/00 C07K 14/00
US Classification:
530384, 530350, 530380, 530381, 530412
Abstract:
The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.
Dr. Lin graduated from the Sun Yat Sen Univ of Med Sci, Guangzhou, China (242 21 Pr 1/71) in 1983. He works in Bakersfield, CA and specializes in Neurology. Dr. Lin is affiliated with San Joaquin Community Hospital.
Co-authors of the paper are Rice undergraduates Tanvi Varadhachary and Kewang Nan, graduate student Tuo Wang, postdoctoral researchers Jian Lin and Yongsung Ji, alumni Yu Zhu of the University of Akron and Bostjan Genorio of the University of Ljubljana, Slovenia, and research scientist Carter Kittre
Date: Jan 26, 2016
Source: Google
Japan Earthquake: Doomsday? Or Just a Restless Earth?
Last year's earthquake in Haiti was "large but not huge," in the words of Jian Lin of the Woods Hole Oceanographic Institution -- but it just happened to be centered beneath the impoverished capital city of Port-au-Prince. It also was on a fault line that had been relatively quiet for 200 years.