Through global profiling of genes that were expressed soon after p53 expression, we identified a gene termed (JFY1). The protein encoded by (JFY1) was found to be exclusively mitochondrial and to bind to Bcl-2 and Bcl-Xthrough a BH3 domain. Exogenous expression of (JFY1) resulted in an extremely rapid and profound apoptosis that occurred much earlier than that resulting from exogenous expression of p53. Based on its unique expression patterns, p53-dependence, and biochemical properties,(JFY1) is likely to be a direct mediator of p53-associated apoptosis.
Rapid Additive Sintering Of Materials Using Electric Fields
- Adelphi MD, US Jian H. Yu - Belcamp MD, US Jeffrey Zabinski - Havre de Grace MD, US
International Classification:
B22F 3/105 C23C 24/08
Abstract:
Rapid additive sintering of materials using electric fields includes a pair of electrodes including a first and second electrode, a power supply operatively connected to the pair of electrodes, and an area in between the pair of electrodes that holds a material. The first electrode is configured for flash sintering the material. The first electrode may be movable and may include a stylus. The material may include powder and may include any of metallic and ceramic material. Multiple layers of materials may be flash sintered by the first electrode. The first electrode may generate an electric field between the first electrode and the material causes the flash sintering. A nozzle may supply the material at variable speeds. The first electrode may be configured to move at variable speeds and in variable directions. The flash sintering may occur at an electric field between 10-50000 V/cm and an electric current between 0-30A.
Jian C Yu MD 227 Mt Pleasant Rd STE 1, Hauppauge, NY 11788 (631)3600005 (phone), (631)3681113 (fax)
Education:
Medical School China Med Coll, Taichung, Taiwan (385 05 Prior 1/71) Graduated: 1969
Procedures:
Colonoscopy Destruction of Lesions on the Anus Hemorrhoid Procedures Laparoscopic Gallbladder Removal Proctosigmoidoscopy Small Bowel Resection
Conditions:
Benign Polyps of the Colon Anal Fissure Anal or Rectal Abscess Gastrointestinal Hemorrhage Hemorrhoids
Languages:
English
Description:
Dr. Yu graduated from the China Med Coll, Taichung, Taiwan (385 05 Prior 1/71) in 1969. He works in Hauppauge, NY and specializes in Colon & Rectal Surgery and Gastroenterology. Dr. Yu is affiliated with North Shore University Hospital and Saint Catherine Of Siena Medical Center.
Fox Chase Cancer Center 333 Cottman Ave, Philadelphia, PA 19111 (215)7286900 (phone), (215)7282773 (fax)
Education:
Medical School Beijing Med Univ, Beijing City, Beijing, China Graduated: 1987
Languages:
English
Description:
Dr. Yu graduated from the Beijing Med Univ, Beijing City, Beijing, China in 1987. He works in Philadelphia, PA and specializes in Diagnostic Radiology and Nuclear Medicine. Dr. Yu is affiliated with Fox Chase Cancer Center and Temple University Hospital.
Jiaxing National Economic & Technological Development Zone Jiaxing, CN Jul 2010 to May 2012 Enterprise CoordinatorCommercial Aircraft Corporation of China, Ltd
Jul 2009 to Sep 2009 Assistant Officer (Internship)
Education:
University of Pittsburgh Pittsburgh, PA 2012 to 2014 Master's in Industrial EngineeringShanghai Jiao Tong University 2006 to 2010 Bachelor of Science in Aeronautics and Astronautics Engineering