Jian H Yu

US Patent:

20210348905, Nov 11, 2021

Filed:

Jul 20, 2021

Appl. No.:

17/380744

Inventors:

- Washington DC, US
Ashiq A. Quabili - Havre De Grace MD, US
Chih-Tsai Chen - Moorestown NJ, US
Nelson Carey - Cape May NJ, US
Robert P. Kaste - North East MD, US
Patrick O'Connor - Galloway Twp NJ, US
Jian H. Yu - Belcamp MD, US

Assignee:

The Government of the United States of America, as represented by the Secretary of Homeland Security - Washington DC

International Classification:

F42D 5/045
B65D 21/02

Abstract:

An explosive threat mitigation unit (TMU) stands ready to receive a suspected bomb, enclose it, and contain the explosion if one occurs. An operator protects bystanders and surroundings by putting the suspected bomb in a TMU and then closing the TMU. If the bomb goes off, the TMU mitigates the effects of both the blast and the fragments. One variation has a container, a tube, a cap, and a door. The container includes an opening. The tube, arranged in the container, aligns with the opening. The cap slides through the opening and over the tube. The door slides into place to close the opening and enclose the cap within the container.

US Patent:

20210087259, Mar 25, 2021

Filed:

Dec 20, 2018

Appl. No.:

16/770840

Inventors:

- New York NY, US
Yaoxing Huang - Brooklyn NY, US
Jian Yu - New Providence NJ, US

International Classification:

C07K 16/10
C07K 16/28
A61K 39/42
A61P 31/18

Abstract:

In various embodiments, the present invention relates generally to using bispecific antibodies in the prevention and treatment of HIV.

US Patent:

20200393231, Dec 17, 2020

Filed:

Feb 26, 2020

Appl. No.:

16/801381

Inventors:

- Washington DC, US
Ashiq A. Quabili - Havre De Grace MD, US
Chih-Tsai Chen - Moorestown NJ, US
Nelson Carey - Cape May NJ, US
Robert P. Kaste - North East MD, US
Patrick O'Connor - Galloway Twp NJ, US
Jian H. Yu - Belcamp MD, US

Assignee:

The Government of the United States of America, as represented by the Secretary of Homeland Security - Washington DC

International Classification:

F42D 5/045
B65D 21/02

Abstract:

An explosive threat mitigation unit (TMU) stands ready to receive a suspected bomb, enclose it, and contain the explosion if one occurs. An operator protects bystanders and surroundings by putting the suspected bomb in a TMU and then closing the TMU. If the bomb goes off, the TMU mitigates the effects of both the blast and the fragments. One variation has a container, a tube, a cap, and a door. The container includes an opening. The tube, arranged in the container, aligns with the opening. The cap slides through the opening and over the tube. The door slides into place to close the opening and enclose the cap within the container.

US Patent:

20190091768, Mar 28, 2019

Filed:

Sep 27, 2017

Appl. No.:

15/716664

Inventors:

- Adelphi MD, US
Jian H. Yu - Belcamp MD, US
Jeffrey Zabinski - Havre de Grace MD, US

International Classification:

B22F 3/105
C23C 24/08

Abstract:

Rapid additive sintering of materials using electric fields includes a pair of electrodes including a first and second electrode, a power supply operatively connected to the pair of electrodes, and an area in between the pair of electrodes that holds a material. The first electrode is configured for flash sintering the material. The first electrode may be movable and may include a stylus. The material may include powder and may include any of metallic and ceramic material. Multiple layers of materials may be flash sintered by the first electrode. The first electrode may generate an electric field between the first electrode and the material causes the flash sintering. A nozzle may supply the material at variable speeds. The first electrode may be configured to move at variable speeds and in variable directions. The flash sintering may occur at an electric field between 10-50000 V/cm and an electric current between 0-30A.

US Patent:

20180237505, Aug 23, 2018

Filed:

Dec 21, 2017

Appl. No.:

15/850832

Inventors:

- New York NY, US
Yaoxing Huang - Brooklyn NY, US
Jian Yu - New Providence NJ, US

International Classification:

C07K 16/10
C07K 16/28

Abstract:

In various embodiments, the present invention relates generally to using bispecific antibodies in the prevention and treatment of HIV.

US Patent:

20180179299, Jun 28, 2018

Filed:

Jun 2, 2016

Appl. No.:

15/579280

Inventors:

- New York NY, US
Jian YU - New York NY, US
Xin YAO - New York NY, US
Yaoxing HUANG - New York NY, US

International Classification:

C07K 16/46
C07K 16/10
A61P 31/18

Abstract:

Provided are tri-specific fusion antibodies created to target multiple epitopes of the Human Immunodeficiency Virus (HIV). The fusion antibodies provide improved potency and breadth against HIV as compared to monospecific and bispecific antibodies, and additionally provide a high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins.

US Patent:

20170247435, Aug 31, 2017

Filed:

Jan 25, 2017

Appl. No.:

15/414822

Inventors:

- New York NY, US
Yaoxing Huang - Brooklyn NY, US
Jian Yu - New Providence NJ, US

International Classification:

C07K 16/10
C07K 16/28

Abstract:

In various embodiments, the present invention relates generally to using bispecific antibodies in the prevention and treatment of HIV.

US Patent:

20150152167, Jun 4, 2015

Filed:

Dec 2, 2014

Appl. No.:

14/558341

Inventors:

- NEW YORK NY, US
Yaoxing Huang - Brooklyn NY, US
Jian Yu - New Providence NJ, US

International Classification:

C07K 16/10
C07K 16/28

Abstract:

In various embodiments, the present invention relates generally to using bispecific antibodies in the prevention and treatment of HIV.