Jianchang J Li from 926 Maple St, Carlisle, MA 01741, Phone: (978)3180802

Biaryl Sulfonamides And Methods For Using Same
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US Patent:

20050143422, Jun 30, 2005
Filed:

Dec 1, 2004
Appl. No.:

11/001589
Inventors:

Jeremy Levin - New City NY, US
Thomas Rush - Lexington MA, US
Frank Lovering - Acton MA, US
Yonghan Hu - Burlington MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Jun Wu - Arlington MA, US
Rajeev Hotchandani - Somerville MA, US
Jason Xiang - Winchester MA, US
Xuemei Du - Valley Cottage NY, US
Derek Cole - New City NY, US
Steve Tam - Wellesley MA, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K031/445
A61K031/4178
A61K031/4025
C07D049/14
C07D043/14
US Classification:

514332000, 514422000, 514444000, 514471000, 546256000, 548518000, 514400000, 548311100
Abstract:

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.

Biaryl Sulfonamides And Methods For Using Same
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US Patent:

20100137298, Jun 3, 2010
Filed:

Jun 13, 2008
Appl. No.:

12/138752
Inventors:

Jeremy Ian Levin - New City NY, US
Frank Lovering - Acton MA, US
Yonghan Hu - Burlington MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Jun Jun Wu - Arlington MA, US
Rajeev Hotchandani - Somerville MA, US
Jason Shaoyun Xiang - Winchester MA, US
Xuemei Du - Valley Cottage NY, US
Derek Cecil Cole - New City NY, US
Steve Yikkai Tam - Wellesley MA, US
Assignee:

Wyeth - Madison NJ
International Classification:

A61K 31/5377
G01N 33/573
C12N 9/99
A61K 31/4439
A61K 31/425
A61K 31/428
A61K 31/381
A61K 31/343
C07D 413/12
C07D 405/10
C07D 277/02
C07D 275/02
C07D 209/42
C07D 333/52
C07D 307/78
A61P 35/00
US Classification:

5142315, 435 74, 435184, 514339, 514367, 514373, 514443, 514469, 544153, 5462841, 548200, 548214, 548492, 549 57, 549468
Abstract:

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.

Tricyclic Compounds As Matrix Metalloproteinase Inhibitors
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US Patent:

20100227859, Sep 9, 2010
Filed:

May 5, 2008
Appl. No.:

12/598868
Inventors:

Wei LI - Acton MA, US
Jianchang Li - Acton MA, US
Yuchuan Wu - Acton MA, US
Junjun Wu - Billerica MA, US
Rajeev Hotchandani - Watertown MA, US
Steve Yikkai Tam - Wellesley MA, US
Tarek Suhayl - Mansour NY, US
Joseph P. Sypek - Waban MA, US
Iain McFadyen - Medford MA, US
International Classification:

A61K 31/5377
C07D 407/04
A61K 31/343
C07D 413/14
C07D 417/14
A61K 31/497
A61P 19/02
A61P 9/10
A61P 11/06
A61P 35/00
A61P 3/04
A61P 3/10
US Classification:

5142328, 549461, 514468, 544140, 544369, 51425402
Abstract:

The present teachings relate to compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, R4, X, and Y are as defined herein. The present teachings also provide methods of making the compounds of formula I and methods of inhibiting matrix metalloproteinases, in particular, MMP-12, that may be involved in pathological disorders found in mammals, including a human.

Name / Title

Company / Classification

Phones & Addresses

Jianchang Li
Director, Principal

JYJ ENTERPRISE INC
Business Services

926 Maple St, Carlisle, MA 01741

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Position:

Principle Scientist at Wyeth

Location:

Greater Boston Area

Industry:

Pharmaceuticals

Work:

Wyeth
Principle Scientist

Jianchang J Li