Jianping P Chao from North Wales, PA, age 58

Us Patents

Farnesyl Protein Transferase Inhibitors
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US Patent:

6372747, Apr 16, 2002
Filed:

Dec 16, 1999
Appl. No.:

09/465553
Inventors:

Arthur G. Taveras - Denville NJ
Ronald J. Doll - Maplewood NJ
Alan B. Cooper - West Caldwell NJ
Johan A. Ferreira - Bensalem PA
Timothy Guzi - Chatham NJ
Dinanath F. Rane - Morganville NJ
Viyyoor M. Girijavallabhan - Parsippany NJ
Cynthia J. Aki - Rutherford NJ
Jianping Chao - Summit NJ
Carmen Alvarez - Roselle Park NJ
Joseph M. Kelly - Parlin NJ
Tarik Lalwani - Philadelphia PA
Jagdish A. Desai - Spotswood NJ
James J-S Wang - Westfield NJ
Assignee:

Schering Corporation - Kenilworth NJ
International Classification:

A61K 31496
US Classification:

51425303, 51425405, 51425501, 514252, 514290, 514326, 544361, 544370, 546 93, 546210
Abstract:

Disclosed are compounds of the formula: wherein R represents an imidazole ring; R represents a carbamate, urea, amide or sulfonamide group; R represents H when the alkyl chain between the amide group and the R imidazole group is substituted, or R represents a substituent such as arylalkyl, heteroarylalkyl or cycloalkyl; and the remaining substituents are as defined herein. Also disclosed are compounds wherein R is H, and the alkyl chain between the amide group and the R imidazole group is unsubstituted. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.

Inhibitors Of Farnesyl-Protein Transferase
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US Patent:

6432959, Aug 13, 2002
Filed:

Dec 22, 1999
Appl. No.:

09/469465
Inventors:

Alan B. Cooper - West Caldwell NJ
Ronald J. Doll - Maplewood NJ
Johan A. Ferreira - Bensalem PA
Ashit Ganguly - Upper Montclair NJ
Viyyoor M. Girijavallabhan - Parsippany NJ
Arthur G. Taveras - Denville NJ
Jianping Chao - Summit NJ
John J. Baldwin - Gwynedd Valley PA
Chia-Yu Huang - Plainsboro NJ
Ge Li - Lawrenceville NJ
Assignee:

Schering Corporation - Kenilworth NJ
International Classification:

A61K 31496
US Classification:

51425309, 51425402, 51425405, 544364, 544367, 544370
Abstract:

Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.

Farnesyl Protein Transferase Inhibitors
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US Patent:

6740661, May 25, 2004
Filed:

Dec 20, 2001
Appl. No.:

10/026999
Inventors:

Arthur G. Taveras - Denville NJ
Ronald J. Doll - Maplewood NJ
Alan B. Cooper - West Caldwell NJ
Johan A. Ferreira - Bensalem PA
Timothy Guzi - Chatham NJ
Alan K. Mallams - Hackettstown NJ
Dinanath F. Rane - Morganville NJ
Viyyoor M. Girijavallabhan - Parsippany NJ
Adriano Afonso - West Caldwell NJ
Cynthia J. Aki - Rutherford NJ
Jianping Chao - Summit NJ
Carmen Alvarez - Roselle Park NJ
Joseph M. Kelly - Parlin NJ
Tarik Lalwani - Philadelphia PA
Jagdish A. Desai - Spotswood NJ
James J-S Wang - Westfield NJ
Jay Weinstein - Upper Montclair NJ
Assignee:

Schering Corporation - Kenilworth NJ
International Classification:

A61K 314545
US Classification:

514290, 514326, 51425501, 51425211, 51425303, 51425405, 514256, 546 93, 546210, 544361, 544370, 544333, 544357
Abstract:

Disclosed are compounds of the formula: wherein R represents an imidazole ring; R represents a carbamate, urea, amide or sulfonamide group; R represents H when the alkyl chain between the amide group and the R imidazole group is substituted, or R represents a substituent such as arylalkyl, heteroarylalkyl or cycloalkyl; and the remaining substituents are as defined herein. Also disclosed are compounds wherein R is H, and the alkyl chain between the amide group and the R imidazole group is unsubstituted. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.

Farnesyl Protein Transferase Inhibitors
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US Patent:

6800636, Oct 5, 2004
Filed:

Dec 20, 2001
Appl. No.:

10/028251
Inventors:

Timothy Guzi - Chatham NJ
Dinanath F. Rane - Morganville NJ
Alan K. Mallams - Hackettstown NJ
Alan B. Cooper - West Caldwell NJ
Ronald J. Doll - Maplewood NJ
Viyyoor M. Girijavallabhan - Parsippany NJ
Arthur G. Taveras - Denville NJ
Corey Strickland - North Plainfield NJ
Joseph M. Kelly - Parlin NJ
Jianping Chao - Summit NJ
Assignee:

Schering Corporation - Kenilworth NJ
International Classification:

A61K 314545
US Classification:

514290, 514325, 51425302, 51421705, 5142282, 5142328, 514218, 546 93, 546195, 546203, 540544, 540598, 540575, 544 60, 544121, 544361, 544370, 544360
Abstract:

Disclosed are compounds of the formula: wherein R represents a cyclic moiety to which is bound an imodazolylalkyl group; R represents a carbamate, urea, amide or sulfonamide group; and the remaining substituents are as defined herein. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.

3,4-Di-Substituted Pyridazinediones As Cxc Chemokine Receptor Antagonists
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US Patent:

6878709, Apr 12, 2005
Filed:

Jan 2, 2003
Appl. No.:

10/335789
Inventors:

Arthur G. Taveras - Denville NJ, US
Michael Dwyer - Scotch Plains NJ, US
Jianping Chao - Summit NJ, US
John J. Baldwin - Gwynedd Valley PA, US
J. Robert Merritt - Ewing NJ, US
Ge Li - Shanghai, CN
Jianhua Chao - Pompton Lakes NJ, US
Younong Yu - Piscataway NJ, US
Assignee:

Schering Corporation - Kenilworth NJ
Pharmacopeia Drug Discovery, Inc. - Princeton NJ
International Classification:

A61K031/50
A61K031/501
C07D237/22
C07D405/12
C07D409/12
US Classification:

514247, 51425201, 51425205, 544238, 544240
Abstract:

Disclosed are compounds of the formula (I) or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

3,4-Di-Substituted Maleimide Compounds As Cxc Chemokine Receptor Antagonists
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US Patent:

6903131, Jun 7, 2005
Filed:

Oct 11, 2002
Appl. No.:

10/269775
Inventors:

Arthur G. Taveras - Denville NJ, US
Michael Dwyer - Scotch Plains NJ, US
Johan A. Ferreira - Bethlehem PA, US
Viyyoor M. Girijavallabhan - Parsippany NJ, US
Jianping Chao - Summit NJ, US
John J. Baldwin - Gwynedd Valley PA, US
J. Robert Merritt - Ewing NJ, US
Ge Li - Shanghai, CN
Assignee:

Schering Corporation - Kenilworth NJ
Pharmacopeia Drug Discovery, Inc. - Cranbury NJ
International Classification:

A61K031/4015
C07D409/12
US Classification:

514425, 548517, 548527, 548406, 548204, 514422
Abstract:

Disclosed are compounds of the formula (I) or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

3,4-Di-Substituted Cyclobutene-1,2-Diones As Cxc-Chemokine Receptor Ligands
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US Patent:

7132445, Nov 7, 2006
Filed:

Jul 30, 2003
Appl. No.:

10/630258
Inventors:

Arthur G. Taveras - Denville NJ, US
Cynthia J. Aki - Livingston NJ, US
Richard W. Bond - Union NJ, US
Jianping Chao - Summit NJ, US
Michael Dwyer - Scotch Plains NJ, US
Johan A. Ferreira - Bethlehem PA, US
Jianhua Chao - Pompton Lakes NJ, US
Younong Yu - Scotch Plains NJ, US
John J. Baldwin - Gwynedd Valley PA, US
Bernd Kaiser - Wallingford CT, US
Ge Li - Shanghai, CN
J. Robert Merritt - Ewing NJ, US
Purakkattle J. Biju - Scotch Plains NJ, US
Laura L. Rokosz - Union NJ, US
James P. Jakway - Bridgewater NJ, US
Gaifa Lai - Edison NJ, US
Minglang Wu - Monmouth Junction NJ, US
Evan A. Hecker - Austin TX, US
Daniel Lundell - Flemington NJ, US
Jay S. Fine - Bloomfield NJ, US
Assignee:

Schering Corporation - Kenilworth NJ
Pharmacopeia Drug Discovery, Inc. - Cranbury NJ
International Classification:

A61K 31/341
A61K 31/343
A61K 31/381
C07D 333/10
C07D 33/72
US Classification:

514438, 514443, 514469, 514471, 549 58, 549 77, 549469, 549494
Abstract:

There are disclosed compounds of the formula.

3,4-Di-Substituted Cyclobutene-1,2-Diones As Cxc-Chemokine Receptor Ligands
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US Patent:

7947720, May 24, 2011
Filed:

Jan 13, 2009
Appl. No.:

12/352781
Inventors:

Arthur G. Taveras - Southborough MA, US
Cynthia J. Aki - Livingston NJ, US
Richard W. Bond - Union NJ, US
Jianping Chao - Summit NJ, US
Michael Dwyer - Scotch Plains NJ, US
Johan A. Ferreira - Bensalem PA, US
Jianhua Chao - Pompton Lakes NJ, US
Younong Yu - East Brunswick NJ, US
John J. Baldwin - Gwynedd Valley PA, US
Bernd Kaiser - Plainsboro NJ, US
Ge Li - Shanghai, CN
J. Robert Merritt - Ewing NJ, US
Purakkattle J. Biju - Piscataway NJ, US
Laura L. Rokosz - Union NJ, US
Assignee:

Schering Corporation - Kenilworth NJ
Pharmacopeia Drug Discovery - Cranbury NJ
International Classification:

C07D 261/04
C07D 327/04
A01N 43/80
A01N 43/06
US Classification:

514378, 514444, 548246, 549 7
Abstract:

There are disclosed compounds of the formula.

Lawyers & Attorneys

Jianping Chao - Lawyer

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Licenses:

New Jersey - Active 2003

Jianping Chao, Summit NJ - Lawyer

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Address:

Chao & Associates
Po Box 423, Summit, NJ 07902
(908)5220503 (Office)

Licenses:

New York - Currently registered 2004

Education:

Rutgers

Jianping P Chao

Jianping Chao Phones & Addresses

Us Patents

Farnesyl Protein Transferase Inhibitors

Inhibitors Of Farnesyl-Protein Transferase

Farnesyl Protein Transferase Inhibitors

Farnesyl Protein Transferase Inhibitors

3,4-Di-Substituted Pyridazinediones As Cxc Chemokine Receptor Antagonists

3,4-Di-Substituted Maleimide Compounds As Cxc Chemokine Receptor Antagonists

3,4-Di-Substituted Cyclobutene-1,2-Diones As Cxc-Chemokine Receptor Ligands

3,4-Di-Substituted Cyclobutene-1,2-Diones As Cxc-Chemokine Receptor Ligands

Lawyers & Attorneys

Jianping Chao - Lawyer

Jianping Chao, Summit NJ - Lawyer

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