Composite materials that contain formaldehyde-free, cured binder compositions are disclosed. Also disclosed are methods of making and using composite materials containing formaldehyde-free binder compositions.
Anti-Il-12 Antibody Based Vectors, Host Cells, And Methods Of Production And Uses
Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.
Human Oct-2 Variant Peptide Chains, Nucleic Acids, And Methods
Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.
Cngh0005 Polypeptides, Antibodies, Compositions, Methods And Uses
The present invention relates to at least one novel CNGH0005 polypeptides, antibodies, including isolated nucleic acids that encode at least one CNGH0005 polypeptide or antibody, CNGH0005 vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
Engineered Anti-Target Immunoglobulin Derived Proteins, Compositions, Methods And Uses
The present invention relates to anti-target immunoglobulin derived proteins, including isolated nucleic acids that encode at least one anti-target Ig derived protein, target, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
Method And Apparatus For Analyzing And Generating Human Antibody Amino Acid And Nucleic Acid Sequences
The invention provides methods, computer programs, data and databases, computer readable media, computer systems, and/or apparatus that use, compare or generate data corresponding to at least one partial antibody or antibody fusion protein nucleic acid or amino acid sequence, on recordable media or in computer memory, such as engineered antibody or antibody fusion protein sequences that include any combination of partial antibody sequences, as well as comparisons between different human antibody partial or full sequences, wherein the present invention can be used, inter alia, for research, diagnostic and/or therapeutic products, methods and devices.
Design And Generation Of Human De Novo Pix Phage Display Libraries
Ping Tsui - Berwyn PA, US Lei Shi - Radnor PA, US Jin Lu - Radnor PA, US John Wheeler - Radnor PA, US Brian Whitaker - Radnor PA, US Lionella Borozdina-Birch - San Diego CA, US Juan C. Almagro - Radnor PA, US Bernard Amegadzie - Radnor PA, US Mark Tornetta - Radnor PA, US Ramachandra Reddy - Radnor PA, US David M. Knight - Radnor PA, US Jinquan Luo - Radnor PA, US Raymond W. Sweet - Radnor PA, US Qiang Chen - San Diego CA, US
Described and claimed herein are combinatorial synthetic Fab libraries displayed on a phage pIX protein. The libraries were built on scaffolds representing the most frequently used genes in human antibodies, which were diversified to mirror the variability of natural antibodies. After selection using a diverse panel of proteins, numerous specific and high-affinity Fabs were isolated. By a process called in-line maturation the affinity of some antibodies was improved up to one hundred-fold yielding low pM binders suitable for in vivo use. This work thus demonstrates the feasibility of displaying complex Fab libraries as pIX-fusion proteins for antibody discovery and lays the foundations for studies on the structure-function relationship of antibodies.
QC Supervisor at ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company
Location:
Somerville, New Jersey
Industry:
Pharmaceuticals
Work:
ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company since 2011
QC Supervisor
ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company 2008 - 2011
QC Scientist II
ImClone Systems 2006 - 2008
QC Scientist
Education:
City University of New York Graduate Center 2001 - 2003
MS, Biochemistry
Nankai University 1993 - 1997
BS
Preclinical At Inhibitex, A Wholly Owned Subsidiary Of Bristol-Myers Squibb