Jin J Lu from 1600 Arch St APT 812, Philadelphia, PA 19103, age 35

Us Patents

Composite Materials And Methods Of Making The Same
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US Patent:

7405169, Jul 29, 2008
Filed:

Oct 4, 2006
Appl. No.:

11/543172
Inventors:

Jin Lu - North Wales PA, US
Assignee:

Rohm and Hass Company - Philadelphia PA
International Classification:

B32B 5/02
B32B 9/04
US Classification:

442154, 442157, 428446, 428447
Abstract:

Composite materials that contain formaldehyde-free, cured binder compositions are disclosed. Also disclosed are methods of making and using composite materials containing formaldehyde-free binder compositions.

Anti-Il-12 Antibody Based Vectors, Host Cells, And Methods Of Production And Uses
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US Patent:

7736650, Jun 15, 2010
Filed:

Dec 21, 2005
Appl. No.:

11/722281
Inventors:

Jin Lu - Boothwyn PA, US
Thomas Nesspor - Collegeville PA, US
Bernard Scallon - Wayne PA, US
Linda Snyder - Pottstown PA, US
Assignee:

Centocor, Inc. - Malvern PA
International Classification:

A61K 39/395
C07H 21/02
C07H 21/04
C12N 15/00
C12N 5/00
C12N 5/02
C12N 5/06
C12N 5/10
C12P 21/04
US Classification:

4241721, 536 231, 536 235, 4353201, 435325, 435 696
Abstract:

Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.

Anti-Il-12 Antibody Based Vectors, Host Cells, And Methods Of Production And Uses
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US Patent:

8361474, Jan 29, 2013
Filed:

Apr 13, 2010
Appl. No.:

12/759154
Inventors:

Jin Lu - Boothwyn PA, US
Thomas Nesspor - Collegeville PA, US
Bernard Scallon - Wayne PA, US
Linda Snyder - Pottstown PA, US
Assignee:

Centocor, Inc. - Malvern PA
International Classification:

A61K 39/395
C07H 21/02
C07H 21/04
C12N 15/00
C12N 5/00
C12N 5/02
C12N 5/10
C12P 21/04
US Classification:

4241721, 536 231, 536 235, 4353201, 435325, 435 696
Abstract:

Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.

Cngh0005 Polypeptides, Antibodies, Compositions, Methods And Uses
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US Patent:

20050008638, Jan 13, 2005
Filed:

Jun 25, 2003
Appl. No.:

10/603313
Inventors:

Jin Lu - Boothwyn PA, US
Li Yan - Wayne PA, US
Chris Huang - Paoli PA, US
Marian Nakada - Malvern PA, US
International Classification:

C12Q001/68
C07H021/04
A61K039/395
C12N009/00
C07K016/40
C12P021/02
C12N005/06
US Classification:

424145100, 435006000, 536023200, 435069100, 435183000, 435320100, 435325000, 530388260
Abstract:

The present invention relates to at least one novel CNGH0005 polypeptides, antibodies, including isolated nucleic acids that encode at least one CNGH0005 polypeptide or antibody, CNGH0005 vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.

Engineered Anti-Target Immunoglobulin Derived Proteins, Compositions, Methods And Uses
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US Patent:

20050033029, Feb 10, 2005
Filed:

Jun 21, 2004
Appl. No.:

10/872932
Inventors:

Jin Lu - Boothwyn PA, US
International Classification:

C07K016/00
US Classification:

530388100
Abstract:

The present invention relates to anti-target immunoglobulin derived proteins, including isolated nucleic acids that encode at least one anti-target Ig derived protein, target, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.

Method And Apparatus For Analyzing And Generating Human Antibody Amino Acid And Nucleic Acid Sequences
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US Patent:

20060088845, Apr 27, 2006
Filed:

Mar 28, 2005
Appl. No.:

11/091234
Inventors:

Jin Lu - Boothwyn PA, US
International Classification:

C12Q 1/68
G01N 33/53
G06F 19/00
US Classification:

435006000, 435007100, 702019000
Abstract:

The invention provides methods, computer programs, data and databases, computer readable media, computer systems, and/or apparatus that use, compare or generate data corresponding to at least one partial antibody or antibody fusion protein nucleic acid or amino acid sequence, on recordable media or in computer memory, such as engineered antibody or antibody fusion protein sequences that include any combination of partial antibody sequences, as well as comparisons between different human antibody partial or full sequences, wherein the present invention can be used, inter alia, for research, diagnostic and/or therapeutic products, methods and devices.

Design And Generation Of Human De Novo Pix Phage Display Libraries
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US Patent:

20100021477, Jan 28, 2010
Filed:

Aug 25, 2009
Appl. No.:

12/546850
Inventors:

Ping Tsui - Berwyn PA, US
Lei Shi - Radnor PA, US
Jin Lu - Radnor PA, US
John Wheeler - Radnor PA, US
Brian Whitaker - Radnor PA, US
Lionella Borozdina-Birch - San Diego CA, US
Juan C. Almagro - Radnor PA, US
Bernard Amegadzie - Radnor PA, US
Mark Tornetta - Radnor PA, US
Ramachandra Reddy - Radnor PA, US
David M. Knight - Radnor PA, US
Jinquan Luo - Radnor PA, US
Raymond W. Sweet - Radnor PA, US
Qiang Chen - San Diego CA, US
International Classification:

A61K 39/40
C12N 15/63
C12N 1/21
C07K 14/195
C07K 16/12
C40B 40/02
C40B 30/04
US Classification:

4241641, 4353201, 4352523, 530350, 5303871, 506 14, 506 9
Abstract:

Described and claimed herein are combinatorial synthetic Fab libraries displayed on a phage pIX protein. The libraries were built on scaffolds representing the most frequently used genes in human antibodies, which were diversified to mirror the variability of natural antibodies. After selection using a diverse panel of proteins, numerous specific and high-affinity Fabs were isolated. By a process called in-line maturation the affinity of some antibodies was improved up to one hundred-fold yielding low pM binders suitable for in vivo use. This work thus demonstrates the feasibility of displaying complex Fab libraries as pIX-fusion proteins for antibody discovery and lays the foundations for studies on the structure-function relationship of antibodies.

Vectors, Host Cells, And Methods Of Production And Uses
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US Patent:

20110008321, Jan 13, 2011
Filed:

Oct 24, 2008
Appl. No.:

12/738453
Inventors:

Jill Carton - Radnor PA, US
Jin Lu - Radnor PA, US
Bernard J. Scallon - Radnor PA, US
Linda Snyder - Radnor PA, US
International Classification:

A61K 39/395
C12N 15/63
C12N 5/10
C07K 16/00
C12P 21/00
C12Q 1/68
A61P 43/00
US Classification:

4241301, 4353201, 435325, 435355, 5303871, 435 691, 435 6
Abstract:

Antibody expression vectors and plasmids can incorporate various antibody gene portions for transcription of the antibody DNA and expression of the antibody in an appropriate host cell. The expression vectors and plasmids have restriction enzyme sites that facilitate ligation of antibody-encoding DNA into the vectors. The vectors incorporate enhancer and promoter sequences that can be varied to interact with transcription factors in the host cell and thereby control transcription of the antibody-encoding DNA. A kit can incorporate these vectors and plasmids.

Resumes

Director

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Location:

3756 Old Post Cir, Swarthmore, PA

Industry:

Pharmaceuticals

Work:

Incyte
Director
Incyte
Associate Director
Johnson & Johnson Jan 2002 - Apr 2015
Principal Scientist
Centocor 2008 - 2010
Head of Informatics For Biologics Coe
Centocor May 2005 - May 2008
Principal Research Scientist

Education:

Shanghai Jiao Tong University
Bachelors, Bachelor of Science, Biomedical Engineering, Medicine The University of Texas Medical Branch
Doctorates, Doctor of Philosophy, Physiology, Neuroscience Villanova University
Master of Science, Masters, Applied Statistics

Skills:

Bioinformatics
Biomarker Discovery
Drug Discovery
Protein Chemistry
Antibodies
Drug Development
Immunology
Proteomics
Dna Sequencing
Sequence Analysis
Assay Development
Flow Cytometry
Oncology
Biomarkers
Genomics
Microarray
Cell
In Vitro
Translational Research
High Throughput Screening
Systems Biology
Monoclonal Antibodies
Certified Project Manage Professional
Informatics
Translational Medicine
Cell Biology
Lims

Languages:

Mandarin
English

Certifications:

Pmp
License 1438125

Senior Research Scientist

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Location:

Philadelphia, PA

Industry:

Chemicals

Work:

Arkema Jun 2016 - Jul 2017
Manager, Business Development
Arkema Jun 2016 - Jul 2017
Senior Research Scientist
Arkema Sartomer Business Group 2011 - 2016
Manager, Adhesives, Sealants and Personal Care R and D Platforms; Global Asp Technical Leader
Sartomer Jul 2006 - Jul 2011
Technical Leader, Oligomer Group
Trillion Science Jan 2006 - Jun 2006
Senior Technical Manager

Education:

Drexel University's Lebow College of Business 2011 - 2013
Master of Business Administration, Masters, Finance University of Pennsylvania 2001 - 2002
North Carolina State University 1997 - 2001
Doctorates, Doctor of Philosophy Institute of Chmistry, the Chinese Academy of Sciences 1994 - 1997
Master of Science, Masters, Physics Tongji University 1989 - 1994
Bachelors, Bachelor of Science, Materials Science, Engineering

Skills:

Polymers
Coatings
Chemistry
Adhesives
Product Development
R&D
Commercialization
Spectroscopy
Polymer Science
Cross Functional Team Leadership
Strategy
Raw Materials
Manufacturing
Polyurethane
Materials Science
Materials
Plastics
Research and Development
Chemical Engineering
New Markets Development
Polymer Chemistry
Strategic Planning
Business Development