George Chiu - Bridgewater NJ, US Shengjian Li - Belle Mead NJ, US Peter J. Connolly - New Providence NJ, US Virginia L. Pulito - Flemington NJ, US Jingchun Liu - Three Bridges NJ, US Steven A. Middleton - Flemington NJ, US
Assignee:
Janssen Pharmaceutica N.V.
International Classification:
A61K 31/496 C07D 213/74
US Classification:
51425312, 544360
Abstract:
The present invention relates to piperazine substituted cyclohexane-1,4-diamine compounds of Formula (I).
George Chiu - Bridgewater NJ, US Shengjian Li - Belle Mead NJ, US Peter Connolly - New Providence NJ, US Virginia Pulito - Flemington NJ, US Jingchun Liu - Three Bridges NJ, US Steven Middleton - Flemington NJ, US
International Classification:
A61K 31/454 A61K 31/445 C07D 401/02 C07D 211/26
US Classification:
514317000, 514326000, 546229000, 546207000
Abstract:
The present invention relates to piperidine substituted cyclohexane-1,4-diamine compounds of Formula (I) and pharmaceutically acceptable forms thereof, as α/αadrenoreceptor modulators for the treatment of benign prostatic hypertrophy and lower urinary tract symptoms. The present invention also relates to pharmaceutical compositions comprising said new compounds, new processes to prepare these new compounds and new uses as a medicine as well as method of treatments.
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