Jing Lu

US Patent:

7198894, Apr 3, 2007

Filed:

Nov 30, 2001

Appl. No.:

09/998481

Inventors:

Francis Barany - New York NY, US
Weiguo Cao - Central SC, US
Jianmin Huang - Jackson Heights NY, US
Jing Lu - Central SC, US

Assignee:

Cornell Research Foundation, Inc. - Ithaca NY

International Classification:

C12Q 1/68
C12P 19/34

US Classification:

435 6, 435 911, 435 912, 435 9152, 204450

Abstract:

The present invention is a method for detecting DNA sequence differences including single nucleotide mutations or polymorphisms, one or more nucleotide insertions, and one or more nucleotide deletions. Labeled heteroduplex PCR fragments containing base mismatches are prepared. Endonuclease cleaves the heteroduplex PCR fragments both at the position containing the variation (one or more mismatched bases) and to a lesser extent, at non-variant (perfectly matched) positions. Ligation of the cleavage products with a DNA ligase corrects non-variant cleavages and thus substantially reduces background. This is then followed by a detection step in which the reaction products are detected, and the position of the sequence variations are determined.

US Patent:

7807431, Oct 5, 2010

Filed:

Mar 5, 2007

Appl. No.:

11/682172

Inventors:

Francis Barany - New York NY, US
Weiguo Cao - Central SC, US
Jianmin Huang - Jackson Heights NY, US
Jing Lu - Tucker GA, US

Assignee:

Cornell Research Foundation, Inc. - Ithaca NY

International Classification:

C12N 9/22

US Classification:

435199, 536 232

Abstract:

The present invention is a method for detecting DNA sequence differences including single nucleotide mutations or polymorphisms, one or more nucleotide insertions, and one or more nucleotide deletions. Labeled heteroduplex PCR fragments containing base mismatches are prepared. Endonuclease cleaves the heteroduplex PCR fragments both at the position containing the variation (one or more mismatched bases) and to a lesser extent, at non-variant (perfectly matched) positions. Ligation of the cleavage products with a DNA ligase corrects non-variant cleavages and thus substantially reduces background. This is then followed by a detection step in which the reaction products are detected, and the position of the sequence variations are determined.

US Patent:

7960159, Jun 14, 2011

Filed:

Sep 2, 2010

Appl. No.:

12/874255

Inventors:

Francis Barany - New York NY, US
Weiguo Cao - Central SC, US
Jianmin Huang - Jackson Heights NY, US
Jing Lu - Tucker GA, US

Assignee:

Corneil Research Foundation, Inc. - Ithaca NY

International Classification:

C12N 9/22

US Classification:

435199, 536 232

Abstract:

The present invention is a method for detecting DNA sequence differences including single nucleotide mutations or polymorphisms, one or more nucleotide insertions, and one or more nucleotide deletions. Labeled heteroduplex PCR fragments containing base mismatches are prepared. Endonuclease cleaves the heteroduplex PCR fragments both at the position containing the variation (one or more mismatched bases) and to a lesser extent, at non-variant (perfectly matched) positions. Ligation of the cleavage products with a DNA ligase corrects non-variant cleavages and thus substantially reduces background. This is then followed by a detection step in which the reaction products are detected, and the position of the sequence variations are determined.

US Patent:

20220401925, Dec 22, 2022

Filed:

Jun 8, 2022

Appl. No.:

17/805914

Inventors:

- London, GB
Jing LU - Wayne PA, US
Michael HOWARD - Wayne PA, US

International Classification:

B01J 23/42
F01N 3/10
B01J 21/04
B01J 23/46
B01J 23/10

Abstract:

A method of manufacturing a catalyst article, the method comprising: providing a complex of a polyphenol and a PGM, the PGM comprising rhodium and/or platinum, the polyphenol comprising an ester functional group; providing a support material; applying the complex to the support material to form a loaded support material; disposing the loaded support material on a substrate; and heating the loaded support material to form nanoparticles of the PGM on the support material.

US Patent:

20220401926, Dec 22, 2022

Filed:

Jun 8, 2022

Appl. No.:

17/805918

Inventors:

- London, GB
Jing LU - Wayne PA, US
Michael HOWARD - Wayne PA, US

International Classification:

B01J 23/44
B01J 23/46
B01J 21/04
B01J 23/10
B01J 35/00
B01J 35/04
B01J 37/02
B01J 37/08
B01D 53/94

Abstract:

A method of manufacturing a catalyst article, the method comprising: providing a complex of a polyphenol and a PGM, the polyphenol comprising an ester functional group, the PGM comprising palladium; providing a support material; applying the complex to the support material to form a loaded support material; disposing the loaded support material on a substrate; and heating the loaded support material to form nanoparticles of the PGM on the support material.

US Patent:

20220297095, Sep 22, 2022

Filed:

Mar 8, 2022

Appl. No.:

17/653937

Inventors:

- London, GB
Jing LU - Wayne PA, US
Michael HOWARD - Wayne PA, US

International Classification:

B01J 23/46
B01J 21/04
B01J 37/03
B01J 37/00
B01J 37/08
B01J 37/04
B01J 23/10
B01J 35/00
B01J 23/42
B01J 23/44
B01J 35/04
B01D 53/94
F01N 3/10
F01N 3/28
F01N 13/18

Abstract:

A method of manufacturing a catalyst article, the method comprising: providing a complex of a polyamine and a PGM; providing a support material; applying the complex to the support material to form a loaded support material; disposing the loaded support material on a substrate; and heating the loaded support material to form nanoparticles of the PGM on the support material.

US Patent:

20230129600, Apr 27, 2023

Filed:

Oct 25, 2022

Appl. No.:

18/049371

Inventors:

- London, GB
Jing LU - Wayne PA, US
Michael HOWARD - Wayne PA, US

International Classification:

B01J 37/08
B01J 21/06
B01J 21/04
B01J 35/04
B01J 31/12
B01D 53/94

Abstract:

A method of manufacturing a catalyst article, the method comprising: providing a complex of a maleic acid-containing polymer and a PGM; providing a support material; applying the complex to the support material to form a loaded support material; disposing the loaded support material on a substrate; and heating the loaded support material to form nanoparticles of the PGM on the support material.

US Patent:

20210299643, Sep 30, 2021

Filed:

Mar 25, 2021

Appl. No.:

17/301109

Inventors:

- London, GB
Hai-Ying CHEN - Wayne PA, US
Joseph FEDEYKO - Wayne PA, US
Neil GREENHAM - Royston, GB
Matthew HARRIS - Royston, GB
Jing LU - Wayne PA, US

International Classification:

B01J 29/76
B01J 37/02
B01J 29/44
B01J 29/80
B01J 35/10
B01J 29/78
B01D 53/94

Abstract:

The invention relates to a catalytic article comprising a substrate having an inlet and an outlet; a first coating comprising a blend of: (1) platinum on a support, and (2) a first SCR catalyst comprising a Cu- and Mn-exchanged molecular sieve; and a second coating comprising a second SCR catalyst; wherein the support comprises at least one of a zeolite or a SiO-AlOmixed oxide. The platinum may be fixed on the support in solution.