Jing Yang

US Patent:

7205329, Apr 17, 2007

Filed:

Jul 18, 2005

Appl. No.:

11/183626

Inventors:

G. Todd Milne - Brookline MA, US
Mark G. Currie - Sterling MA, US
John Jeffrey Talley - Somerville MA, US
Brian M. Cali - Arlington MA, US
Barbara Chen - Braintree MA, US
Craig Zimmerman - Topsfield MA, US
Jing Jing Yang - Boxborough MA, US

Assignee:

Microbia, Inc. - Cambridge MA

International Classification:

A61K 31/405
C07D 209/12

US Classification:

514415, 548469

Abstract:

Modulators of the CRTH2 receptor and their use in the treatment of various disorders, including asthma are described.

US Patent:

8088590, Jan 3, 2012

Filed:

Dec 28, 2006

Appl. No.:

11/646706

Inventors:

Sendurai Mani - Cambridge MA, US
Jing Yang - Cambridge MA, US
Robert A. Weinberg - Brookline MA, US

Assignee:

Whiteland Institute for Biomedical Research - Cambridge MA

International Classification:

G01N 33/574
C12Q 1/68

US Classification:

435 723, 435 6, 435 71

Abstract:

The invention relates to methods and compositions for inhibiting metastasis, such as by inhibiting FOXC2 expression or activity. The invention further relates to methods of prognosticating, diagnosing, and assisting in the diagnosis of metastasis in an individual, or of determining the metastatic potential of a tumor. The invention further relates to methods of identifying agents which inhibit metastasis.

US Patent:

8568998, Oct 29, 2013

Filed:

Dec 1, 2011

Appl. No.:

13/309067

Inventors:

Sendurai Mani - Cambridge MA, US
Jing Yang - Cambridge MA, US
Robert A. Weinberg - Cambridge MA, US

Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA

International Classification:

G01N 33/574
A61K 49/00

US Classification:

435 723, 435 61, 424 92

Abstract:

The invention relates to methods and compositions for inhibiting metastasis, such as by inhibiting FOXC2 expression or activity. The invention further relates to methods of prognosticating, diagnosing, and assisting in the diagnosis of metastasis in an individual, or of determining the metastatic potential of a tumor. The invention further relates to methods of identifying agents which inhibit metastasis.

US Patent:

20040106663, Jun 3, 2004

Filed:

Sep 8, 2003

Appl. No.:

10/657753

Inventors:

John Talley - Somerville MA, US
Angelika Fretzen - Somerville MA, US
Craig Zimmerman - Topsfield MA, US
Timothy Barden - Salem MA, US
Jing Yang - Boxborough MA, US
Eduardo Martinez - Cambridge MA, US
Robert Busby - Weymouth MA, US
Etchell Cordero - North Reading MA, US
Fariba Cipriano - Belmont MA, US
Christine Pierce - Tewksbury MA, US
Eric Summers - Brookline MA, US

International Classification:

A61K031/42
C07D261/14

US Classification:

514/378000, 548/246000

Abstract:

This invention relates to isoxazole-based inhibitors of fungal invasion.

US Patent:

20050234030, Oct 20, 2005

Filed:

Jan 3, 2005

Appl. No.:

11/028896

Inventors:

Wilmin Bartolini - Amesbury MA, US
Brian Cali - Arlington MA, US
Barbara Chen - Watertown MA, US
Mark Currie - Sterling MA, US
G. Milne - Brookline MA, US
James Pearson - Cambridge MA, US
John Talley - Somerville MA, US
Jing Yang - Boxborough MA, US
Craig Zimmerman - Topsfield MA, US

International Classification:

A61K031/53
A61K031/501
A61K031/497
A61K031/541
A61K031/5377
A61K031/496
C07D043/02
C07D417/02
C07D413/02

US Classification:

514183000, 514241000, 514252060, 514255050, 544238000, 544209000, 544405000, 548495000, 514419000, 514227500, 514232200, 514254050, 544060000, 544373000, 544143000, 514406000, 514365000, 514374000, 514414000

Abstract:

Certain substituted indoles that are modulators of one or more or of CRTH2, COX-2 AND FAAH are described. The compounds are useful for treatment of pain and/or inflammation as well as other disorders.

US Patent:

20070161698, Jul 12, 2007

Filed:

Mar 13, 2007

Appl. No.:

11/685542

Inventors:

G. Milne - Brookline MA, US
Mark Currie - Sterling MA, US
John Talley - Somerville MA, US
Brian Cali - Arlington MA, US
Barbara Chen - Braintree MA, US
Craig Zimmerman - Topsfield MA, US
Jing Yang - Boxborough MA, US

International Classification:

A61K 31/405

US Classification:

514419000

Abstract:

Modulators of the CRTH2 receptor and their use in the treatment of various disorders, including asthma are described.

US Patent:

20070203209, Aug 30, 2007

Filed:

Aug 18, 2006

Appl. No.:

11/507099

Inventors:

Wilmin Bartolini - Amesbury MA, US
Brian Cali - Arlington MA, US
Barbara Chen - Northbrook IL, US
Mark Currie - Sterling MA, US
G. Milne - Brookline MA, US
James Pearson - Cambridge MA, US
John Talley - Somerville MA, US
Jing Yang - Boxborough MA, US
Craig Zimmerman - Topsfield MA, US
Alex Monreal - Boston MA, US

International Classification:

A61K 31/428
A61K 31/405
C07D 417/02
C07D 209/20

US Classification:

514367000, 514419000, 548498000, 548159000

Abstract:

Indoles having various activities, including indoles that are CRTH2 are described. The compounds are useful for treating asthma, neuropathic pain, allegic rhinitis and other disorders.

US Patent:

20090119410, May 7, 2009

Filed:

Nov 28, 2008

Appl. No.:

12/325103

Inventors:

Jing Yang - San Ramon CA, US
Quan Wang - Beijing, CN
Michael Ma - Fremont CA, US
Meichun Zhang - Nanshan Shenzhen, CN

Assignee:

UTSTARCOM, INC. - Alameda CA

International Classification:

G06F 15/16

US Classification:

709231

Abstract:

A media content distribution system for distributed multimedia streaming communicates over a network and incorporates multiple independent media stations, each having a media director for control and a number of media engines for storage, retrieval and streaming of media content. A middleware system employing a execution engine for service platform middleware and a presentation engine for terminal middleware is provided for flexible interfacing with network transport and home network elements respectively and the IPTV applications supported.