Jing Zhu

US Patent:

D4313232, Sep 26, 2000

Filed:

Oct 21, 1999

Appl. No.:

D/112582

Inventors:

James Joel Schultz - New York NY
Jing Yi Zhu - East Rutherford NJ
Werner Fischer - Burk, DE

Assignee:

Revlon Consumer Products Corporation - New York NY

International Classification:

2803

US Classification:

D28 76

US Patent:

20140295424, Oct 2, 2014

Filed:

Mar 21, 2014

Appl. No.:

14/221596

Inventors:

- New York NY, US
Jing Zhu - New York NY, US
Jinho Kim - New York NY, US
John Paul Hilton - New York NY, US
Renjun Pei - Suzhou, CN
Milan N. Stojanovic - Fort Lee NJ, US

Assignee:

The Tustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/68

US Classification:

435 611, 4353031

Abstract:

Techniques for isolating, enriching, and/or amplifying target DNA molecules using MEMS-based microdevices are disclosed. The techniques can be used for detecting single nucleotide polymorphism, and for isolating and enriching desired DNA molecules, such as aptamers.

US Patent:

20140296095, Oct 2, 2014

Filed:

Mar 24, 2014

Appl. No.:

14/223767

Inventors:

- New York NY, US
Jing Zhu - New York NY, US
Milan N. Stojanovic - Fort Lee NY, US
Renjun Pei - Suzhou, CN

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

G01N 33/574

US Classification:

506 9, 435 614, 4352891, 506 16, 4352861

Abstract:

Methods and systems are provided for capturing and releasing target cells. The system includes a microdevice having a microchamber including surface-patterned aptamers capable of binding with the target cells. A sample including target cells is introduced to the microchamber, where the target cells bind to the aptamers at locally regulated temperatures. The captured target cells can be selectively released when the temperature of a region is changed to a second temperature.