Joan H Garbarino

US Patent:

6448391, Sep 10, 2002

Filed:

Jan 14, 2000

Appl. No.:

09/482611

Inventors:

Joan Garbarino - Berkeley CA
William Belknap - Albany CA

Assignee:

The United States of America as represented by the Secretary of Agriculture - Washington DC
Demegen, Inc. - Pittsburgh PA

International Classification:

C07H 2104

US Classification:

536 241

Abstract:

Stabilized ubiquitin-lytic peptide fusion polypeptides and a method of making the same by sub-cloning nucleic acid sequences coding for lytic peptides into a plasmid vector comprising a promoter and ubiquitin polypeptide coding sequence, wherein the ubiquitin polypeptide sequence is linked to the 5â end of the lytic peptide nucleic acid sequence and is translated as a fusion polypeptide.

US Patent:

60181028, Jan 25, 2000

Filed:

Feb 19, 1997

Appl. No.:

8/801028

Inventors:

Joan Garbarino - Berkeley CA
Jesse Jaynes - Raleigh NC
William Belknap - Albany CA

Assignee:

Demegen, Inc. - Pittsburgh PA
The United States of America represented by the Secretary of Agriculture - Washington DC

International Classification:

A01H 100
C07H 2104
C12N 1500
C12N 500

US Classification:

800279

Abstract:

Stabilized ubiquitin-lytic peptide fusion polypeptides and a method of making the same by sub-cloning nucleic acid sequences coding for lytic peptides into a plasmid vector comprising a promoter and ubiquitin polypeptide coding sequence, wherein the ubiquitin polypeptide sequence is linked to the 5' end of the lytic peptide nucleic acid sequence and is translated as a fusion polypeptide.

US Patent:

59555734, Sep 21, 1999

Filed:

Jul 21, 1995

Appl. No.:

8/505486

Inventors:

Joan Garbarino - Berkeley CA
Jesse Jaynes - Raleigh NC
William Belknap - Albany CA

Assignee:

Demegen, Inc. - Durham NC

International Classification:

A61K 3800

US Classification:

530324

Abstract:

Stabilized ubiquitin-lytic peptide fusion polypeptides and a method of making the same by sub-cloning nucleic acid sequences coding for lytic peptides into a plasmid vector comprising a promoter and ubiquitin polypeptide coding sequence, wherein the ubiquitin polypeptide sequence is linked to the 5' end of the lytic peptide nucleic acid sequence and is translated as a fusion polypeptide.