Joel L Stanslaski

US Patent:

6419692, Jul 16, 2002

Filed:

Feb 3, 1999

Appl. No.:

09/243580

Inventors:

Duchuan Yang - Plymouth MN
Joel Stanslaski - New Hope MN
Lixiao Wang - Maple Grove MN

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61F 206

US Classification:

623 115, 623 146, 623 142, 427 221

Abstract:

A medical device, such as a stent or balloon of a balloon catheter which includes a body portion which has an exterior surface which contacts, at least in part, a vessel wall during treatment. The body portion is expandable from a first position, wherein the body portion is sized for insertion into the vessel lumen, to a second position, wherein at least a portion of the exterior surface is in contact with the lumen wall. The medical device includes a first coating disposed over at least a portion of the exterior surface of the body portion with the first coating including a drug or therapeutic substance which is intended for controlled release from the surface. The medical device further includes a second coating overlying at least a substantial portion of the first coating. The second coating includes a material that is generally impervious to elution of the drug or therapeutic substance therethrough when the body portion is in a first position when inserted into the vessel lumen. The material of the second coating is relatively inelastic so that the second coating fractures during expansion of the body portion to the second position to allow elution of therapeutic substance through a multiplicity of fissures formed through the second coating.

US Patent:

6461326, Oct 8, 2002

Filed:

Oct 26, 2000

Appl. No.:

09/696852

Inventors:

Dahuan Yang - Plymouth MN
Joel Stanslaski - New Hope MN
Liguang Tang - Plymouth MN
Joseph Guaire Mary Scanlon - Crystal MN

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61M 2900

US Classification:

604 9601, 2504611

Abstract:

An intraluminal medical device comprised of two or more substrates formed of the same or a different material wherein the substrates are bonded together using a fluorescent dyed adhesive.

US Patent:

6569195, May 27, 2003

Filed:

Jun 18, 2001

Appl. No.:

09/883870

Inventors:

Dachuan Yang - Plymouth MN
Joel L. Stanslaski - New Hope MN
Lixiao Wang - Maple Grove MN
Scott R. Smith - Chaska MN

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61F 206

US Classification:

623 146, 427 225, 427 221

Abstract:

A stent having a polymeric coating for controllably releasing an included active agent. The polymeric coating includes a blend of a first polymeric material, which if alone, would release the agent at a first, higher rate, and a second polymeric material, which if alone would release the agent at a second, lower rate over a longer time period. One stent coating utilizes a faster releasing hydrophilic polymeric material and a slower releasing hydrophobic material. One stent coating includes a blend of a faster releasing PLA-PEO copolymer and a slower releasing PLA-PCL copolymer. One active agent is Taxol. One use of the Taxol delivering stent is to inhibit restenosis following angioplasty.

US Patent:

6589215, Jul 8, 2003

Filed:

Dec 1, 2000

Appl. No.:

09/728589

Inventors:

Dachuan Yang - Plymouth MN
Lixiao Wang - Maple Grove MN
Joel Stanslaski - New Hope MN
Liguang Tang - Plymouth MN

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61M 2500

US Classification:

604265

Abstract:

The present invention relates to a medical device for insertion into the body wherein the device has at least one surface which periodically comes into contact with a second surface. The first surface comprises an improved lubricious coating having a first hydrogel layer and a second hydrophobic top coating which prevents the hydrogel coating from prematurely absorbing too much moisture. The hydrophobic top coating comprises at least one hydrophilic surfactant which acts as a carrier to facilitate removal of the hydrophobic top coating upon entry into an aqueous environment.

US Patent:

6610035, Aug 26, 2003

Filed:

Mar 30, 2001

Appl. No.:

09/822973

Inventors:

Dachuan Yang - Plymouth MN
Lixiao Wang - Maple Grove MN
Joel Stanslaski - New Hope MN
Liguang Tang - Plymouth MN

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61M 2500

US Classification:

604265

Abstract:

The present invention relates to a medical device for insertion into the body wherein the device has at least one surface which periodically comes into contact with a second surface. The first surface comprises an improved lubricious coating having a first hydrogel layer and a second hydrophobic top coating which prevents the hydrogel coating from prematurely absorbing too much moisture. The hydrophobic top coating comprises at least one hydrophilic surfactant which acts as a carrier to facilitate removal of the hydrophobic top coating upon entry into an aqueous environment.

US Patent:

6656156, Dec 2, 2003

Filed:

May 22, 2002

Appl. No.:

10/154186

Inventors:

Dachuan Yang - Plymouth MN
Joel Stanslaski - New Hope MN
Lixiao Wang - Maple Grove MN

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61M 2900

US Classification:

60410302, 60410306, 60410312

Abstract:

The invention relates to a medical device, such as a stent or a balloon catheter that includes an expandable body portion which has an exterior surface that contacts a vessel wall during treatment. The medical device includes a first coating disposed over at least a portion of the exterior surface. The first coating includes a therapeutic substance that is intended for controlled release from the exterior surface. The medical device further includes a second coating overlaying at least a substantial portion of the first coating. The second coating includes a material that is generally impervious to elution of the therapeutic substance therethrough when the body portion is inserted into the vessel lumen. The material of the second coating is relatively inelastic so that the second coating fractures during expansion of the body portion to allow elution of the therapeutic substance through fissures formed in the second coating.

US Patent:

61768499, Jan 23, 2001

Filed:

May 21, 1999

Appl. No.:

9/316502

Inventors:

Dachuan Yang - Plymouth MN
Lixiao Wang - Maple Grove MN
Joel Stanslaski - New Hope MN
Liguang Tang - Plymouth MN

Assignee:

Scimed Life Systems, Inc. - Maple Grove MN

International Classification:

A61M 532

US Classification:

604265

Abstract:

The present invention relates to a medical device for insertion into the body wherein the device has at least one surface which periodically comes into contact with a second surface. The first surface comprises an improved lubricious coating having a first hydrogel layer and a second hydrophobic top coating which prevents the hydrogel coating from prematurely absorbing too much moisture. The hydrophobic top coating comprises at least one hydrophilic surfactant which acts as a carrier to facilitate removal of the hydrophobic top coating upon entry into an aqueous environment.

US Patent:

6258121, Jul 10, 2001

Filed:

Jul 2, 1999

Appl. No.:

9/346975

Inventors:

Dachuan Yang - Plymouth MN
Joel L. Stanslaski - New Hope MN
Lixiao Wang - Maple Grove MN
Scott R. Smith - Chaska MN

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61F 206

US Classification:

623 146

Abstract:

A stent having a polymeric coating for controllably releasing an included active agent. The polymeric coating includes a blend of a first polymeric material, which if alone, would release the agent at a first, higher rate, and a second polymeric material, which if alone would release the agent at a second, lower rate over a longer time period. One stent coating utilizes a faster releasing hydrophilic polymeric material and a slower releasing hydrophobic material. One stent coating includes a blend of a faster releasing PLA-PEO copolymer and a slower releasing PLA-PCL copolymer. One active agent is Taxol. One use of the Taxol delivering stent is to inhibit restenosis following angioplasty.