Joel E Sutton

US Patent:

50987151, Mar 24, 1992

Filed:

Dec 20, 1990

Appl. No.:

7/631741

Inventors:

Terrance T. McCabe - Durham NC
Robert A. Stagner - Greenville NC
Joel E. Sutton - Greenville NC

Assignee:

Burroughs Wellcome Co. - Research Triangle Park NC

International Classification:

A61K 936

US Classification:

424479

Abstract:

The invention comprises a flavored thin film coating on solid oral dosage pharmaceutical tablets containing unpleasant tasting ingredients such as triprolidine hydrochloride and pseudoephedrine hydrochloride. The flavored coating of the invention is comprised of a film-forming substance such as a hydroxypropyl methylcellulose and a polyethylene glycol, a sweetening agent and a flavoring agent. The method of the invention comprises aqueous spray-coating of the flavored sweetened coating onto the pharmaceutical tablets.