John P Bartholomew

US Patent:

20230020138, Jan 19, 2023

Filed:

Sep 15, 2022

Appl. No.:

17/945486

Inventors:

- Columbus OH, US
Gaurav Sharma - Columbus OH, US
Andrew Sweeney - Columbus OH, US
Amy M. Heintz - Dublin OH, US
Stephanie Kute - Columbus OH, US
Nicholas Annetta - Columbus OH, US
Thomas D. Haubert - Columbus OH, US
Steven M. Risser - Reynoldsburg OH, US
Jeffrey Friend - Columbus OH, US
John Bartholomew - Columbus OH, US
Rachel Thurston - Columbus OH, US
Alexander C. Morrow - Gahanna OH, US
George Brand - Columbus OH, US
Jeffrey Ellis - Columbus OH, US
Matthew Mowrer - Columbus OH, US
Raymond Zaborski - Columbus OH, US

International Classification:

A61N 1/05
A61N 1/04
A61B 5/00
A61B 5/11
A61B 5/291
A61B 5/375
A61B 5/389

Abstract:

The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

US Patent:

20210062130, Mar 4, 2021

Filed:

Aug 26, 2020

Appl. No.:

17/002940

Inventors:

- Columbus OH, US
Ryan W. Daly - Columbus OH, US
Dave Seibert - Columbus OH, US
Patrick Norris - Columbus OH, US
John Bartholomew - Columbus OH, US
Sherry K. Blight - Columbus OH, US

International Classification:

C12M 3/06
C12M 1/00
C12M 1/34

Abstract:

A biological culture unit comprises a chamber body and a valve plate. The chamber body has defined therein a growth chamber and an aliquot chamber. The valve plate is disposed on the top surface of the chamber body and is movable to define selectable configurations of the biological culture unit for: (1) loading the growth chamber; (3) transferring an aliquot from the growth chamber to the aliquot chamber via a path defined within the biological culture unit in the transfer position; and (4) extracting the aliquot from the aliquot chamber. The selectable positions may further include (2) a growth position, and (5) a termination position for putting a termination agent into the growth and aliquot chambers. The valve plate may further include a neutralizer port that is aligned with the aliquot chamber in the loading position, for loading a neutralizing agent into the aliquot chamber.

US Patent:

20200276438, Sep 3, 2020

Filed:

May 19, 2020

Appl. No.:

16/877554

Inventors:

- Columbus OH, US
Gaurav Sharma - Columbus OH, US
Andrew Sweeney - Columbus OH, US
Amy M. Heintz - Dublin OH, US
Stephanie Kute - Columbus OH, US
Nicholas Annetta - Columbus OH, US
Thomas D. Haubert - Columbus OH, US
Steven M. Risser - Reynoldsburg OH, US
Jeffrey Friend - Columbus OH, US
John Bartholomew - Columbus OH, US
Rachel Thurston - Columbus OH, US
C. Alexander Morrow - Gahanna OH, US
George Brand - Columbus OH, US
Jeffrey Ellis - Columbus OH, US
Matthew Mowrer - Columbus OH, US
Raymond Zaborski - Columbus OH, US

International Classification:

A61N 1/05
A61B 5/0488
A61N 1/04
A61B 5/00
A61B 5/0478
A61B 5/0482
A61B 5/11

Abstract:

The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.

US Patent:

20190298576, Oct 3, 2019

Filed:

Apr 1, 2019

Appl. No.:

16/371376

Inventors:

- Grand Rapids MI, US
John BARTHOLOMEW - Hilliard OH, US
Steven MADLAND - Columbus OH, US
David HOLLEY - Lancaster OH, US
John P. TALLARICO - Powell OH, US
Corrie BENNISON - Lewis Center OH, US
William G. ATTERBURY - Columbus OH, US
Michael Scott ULRICH - Columbus OH, US
Russell KITTEL - Gahanna OH, US
Jeffrey L. ELLIS - Columbus OH, US
Thomas HAUBERT - Columbus OH, US

International Classification:

A61F 13/00
A61M 1/00

Abstract:

Devices and systems disclosed herein may include a negative pressure pump that includes a reservoir defining a lumen and a longitudinal axis, a piston, and a drive assembly comprising a spring. Motion of the spring may move the piston along the longitudinal axis of the reservoir to create a negative pressure within the reservoir. Methods of manufacturing a negative pressure pump and using a negative pressure pump to remove fluid from a target site are also described.

US Patent:

20180154140, Jun 7, 2018

Filed:

Jun 2, 2016

Appl. No.:

15/578816

Inventors:

- Columbus OH, US
Gaurav Sharma - Columbus OH, US
Andrew Sweeney - Columbus OH, US
Amy M. Heintz - Dublin OH, US
Stephanie Kute - Columbus OH, US
Nicholas Annetta - Columbus OH, US
Thomas D. Haubert - Columbus OH, US
Steven M. Risser - Reynoldsburg OH, US
Jeffrey Friend - Columbus OH, US
John Bartholomew - Columbus OH, US
Rachel Thurston - Columbus OH, US
C. Alexander Morrow - Gahanna OH, US
George Brand - Columbus OH, US
Jeffrey Ellis - Columbus OH, US
Matthew Mowrer - Columbus OH, US
Raymond Zaborski - Columbus OH, US

International Classification:

A61N 1/05
A61B 5/0478
A61B 5/00
A61B 5/0488
A61B 5/11
A61N 1/04

Abstract:

The present disclosure relates to neuromuscular stimulation and sensing cuffs. The neuromuscular stimulation cuff has at least two fingers and a plurality of electrodes disposed on each finger. More generally, the neuromuscular stimulation cuff includes an outer, reusable component and an inner, disposable component. One or more electrodes are housed within the reusable component. The neuromuscular stimulation cuff may be produced by providing an insulating substrate layer, forming a conductive circuit on the substrate layer to form a conductive circuit layer, adhering a cover layer onto the conductive circuit layer to form a flexible circuit, and cutting at least one flexible finger from the flexible circuit. The neuromuscular stimulation cuff employs a flexible multi-electrode design which allows for reanimation of complex muscle movements in a patient, including individual finger movement.