John Kit Carson

US Patent:

6369228, Apr 9, 2002

Filed:

Feb 5, 2001

Appl. No.:

09/777087

Inventors:

John R. Carson - Norristown PA
Philip M. Pitis - North Wales PA
Kathryn E. Rogers - Audubon PA

Assignee:

Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ

International Classification:

C07D21700

US Classification:

546146, 546208

Abstract:

Aroyl aminoacyl pyrroles are pharmaceutically useful in treating neuropathic pain, which includes utility for the treatment of neuropathic pain.

US Patent:

6436959, Aug 20, 2002

Filed:

Dec 23, 1998

Appl. No.:

09/220189

Inventors:

John R. Carson - Norristown PA
Richard J. Carmosin - late of Quakertown PA
Louis J. Fitzpatrick - Souderton PA
Allen B. Reitz - Lansdale PA
Michele C. Jetter - Norristown PA

Assignee:

Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ

International Classification:

A61K 314468

US Classification:

514326, 514329, 546224, 546208

Abstract:

4-[aryl(piperidin-4-yl)]aminobenzamides are delta-opioid receptor agonists/antagonists. As delta-opioid receptor agonists, such compounds are useful as analgesics. Depending on their agonist/antagonist effect, such compounds may also be useful immunosuppressants, antiinflammatory agents, agents for the treatment of mental illness, medicaments for drug and alcohol abuse, agents for treating gastritis and diarrhea, cardiovascular agents, and agents for the treatment of respiratory diseases.

US Patent:

6492387, Dec 10, 2002

Filed:

Dec 11, 2001

Appl. No.:

10/015038

Inventors:

John R. Carson - Norristown PA
Philip M. Pitis - North Wales PA

Assignee:

Ortho-McNeil Pharamaceutical, Inc. - Raritan NJ

International Classification:

C07D 40102

US Classification:

514307, 514416, 546146, 548465

Abstract:

This invention is directed to isoindolyl and isoquinolinyl aroyl pyrrole compounds pharmaceutically useful as agents or modulators for the treatment of central nervous system disorders and methods for the treatment of central nervous system disorders.

US Patent:

6573267, Jun 3, 2003

Filed:

Jun 29, 2001

Appl. No.:

09/896084

Inventors:

John R. Carson - Norristown PA
Philip M. Pitis - North Wales PA

Assignee:

Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ

International Classification:

A61K 3140

US Classification:

51425401, 5142278, 5142355, 514326, 514343, 514397, 514422, 514423, 544 582, 544 585, 544141, 544372, 546208, 5462791, 5483147, 548518, 548527, 548539

Abstract:

This invention is directed to aroyl aminoacyl pyrroles pharmaceutically useful as agents and modulators for the treatment of central nervous system disorders and a method for the treatment of central nervous system disorders including, but not limited to, use of the compounds of the present invention as anticonvulsant agents and modulators, antiepileptic agents and modulators, neuroprotective agents and modulators, muscle relaxant agents and modulators and as agents and modulators for the treatment of neuropathic pain.

US Patent:

6897319, May 24, 2005

Filed:

Dec 10, 2002

Appl. No.:

10/315585

Inventors:

John R. Carson - Norristown PA, US
Ellen E. Codd - Blue Bell PA, US
Philip M. Pitis - North Wales PA, US

Assignee:

Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ

International Classification:

A61K031/4439
A61K031/4178
C07D401/06
C07D401/14
C07D403/06

US Classification:

5462791, 546146, 546168, 5462681, 546256, 5483147, 5483141, 548517, 548518, 548527, 548539, 514343, 514397, 514422, 514314, 514307

Abstract:

This invention is directed to aroyl pyrrole heteroaryl methanone and methanol compounds pharmaceutically useful as agents for treating or modulating a central nervous system disorder and methods for treating or modulating a central nervous system disorder.

US Patent:

6958349, Oct 25, 2005

Filed:

Mar 31, 2003

Appl. No.:

10/403186

Inventors:

John R. Carson - Norristown PA, US
Michele C. Jetter - Norristown PA, US
Jung S. Lee - Ambler PA, US
Mark A. Youngman - Warminster PA, US

Assignee:

Ortho-McNeil Pharmaceuticals, Inc. - Raritan NJ

International Classification:

A61K031/47
C07D215/12
C07D215/16

US Classification:

514314, 546174, 546175, 546177

Abstract:

This invention is directed towards novel alkylamide derivatives as bradykinin receptor antagonists useful for the treatment of bradykinin modulated disorders such as pain, inflammation, asthma and allergy. Furthermore, the present invention is directed to novel alkylamide derivatives as bradykinin receptor agonists useful for the treatment of bradykinin modulated disorders such as hypertension and the like.

US Patent:

7244866, Jul 17, 2007

Filed:

May 11, 2005

Appl. No.:

11/126771

Inventors:

John R. Carson - Norristown PA, US
Philip M. Pitis - North Wales PA, US

Assignee:

Janssen Pharmaceutical N.V. - Beerse

International Classification:

C07C 233/65
A61K 31/165

US Classification:

564164, 514620

Abstract:

This invention is directed to carboxamido opioid compounds pharmaceutically useful as agents for treating or modulating a central nervous system disorder and methods for treating or modulating a central nervous system disorder.

US Patent:

7358261, Apr 15, 2008

Filed:

Dec 16, 2004

Appl. No.:

11/014471

Inventors:

John R. Carson - Norristown PA, US
Michele C. Jetter - Norristown PA, US
Jung S. Lee - Ambler PA, US
Mark A. Youngman - Warminster PA, US

Assignee:

Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ

International Classification:

A61K 31/47
C07D 215/38

US Classification:

514311, 514312, 514314, 546153, 546176, 546178

Abstract:

This invention is directed towards novel alkylamide derivatives as bradykinin receptor antagonists useful for the treatment of bradykinin modulated disorders such as pain, inflammation, asthma and allergy. Furthermore, the present invention is directed to novel alkylamide derivatives as bradykinin receptor agonists useful for the treatment of bradykinin modulated disorders such as hypertension and the like.