John Matthew Cavanagh

US Patent:

20130281503, Oct 24, 2013

Filed:

Apr 26, 2013

Appl. No.:

13/871259

Inventors:

North Carolina State University - , US
John Cavanagh - Cary NC, US
Richele Thompson - Orlando FL, US

Assignee:

North Carolina State University - Raleigh NC

International Classification:

G01N 33/566
A01N 43/90

US Classification:

514387, 435 732, 548255

Abstract:

The present disclosure provides methods and compositions useful for screening agents for activity in modulating response regulator signaling activity, which is, in turn, useful for determining whether these agents modulate biofilm formation or lowers the minimum inhibitory concentration (MIC) of an antibiotic, useful in determining or selecting optimum agents and/or agent dosages in modulating a biofilm of interest or lowering the minimum inhibitory concentration (MIC) of an antibiotic, and useful as a research tool for studying response regulators.

US Patent:

20130315874, Nov 28, 2013

Filed:

Jul 19, 2013

Appl. No.:

13/946523

Inventors:

John Cavanagh - Cary NC, US
David F. Ritchie - Durham NC, US
Steven A. Rogers - Raleigh NC, US
Catherine S. Reed - Raleigh NC, US

Assignee:

North Carolina State University - Raleigh NC

International Classification:

A01N 43/647
A01N 59/20
A01N 63/00

US Classification:

424 936, 514397, 424638

Abstract:

Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator.

US Patent:

20140127273, May 8, 2014

Filed:

Jan 8, 2014

Appl. No.:

14/150024

Inventors:

- Raleigh NC, US
John Cavanagh - Cary NC, US
T. Eric Ballard - Raleigh NC, US
Justin J. Richards - Durham NC, US

Assignee:

North Carolina State University - Raleigh NC

International Classification:

A01N 43/52
A61K 8/49

US Classification:

424400, 5483074, 514395, 424 49

Abstract:

Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.