John L Connelly

Address:

3902 N Proctor St, Tacoma, WA 98407

VIN:

1FMJK1G52AEA29229

Make:

FORD

Model:

EXPEDITION EL

Year:

2010

US Patent:

20210055282, Feb 25, 2021

Filed:

Nov 6, 2020

Appl. No.:

17/091501

Inventors:

- Schenectady NY, US
- Bellevue WA, US
Cathryn Ellen Olsen - Wilton NY, US
John Richard Nelson - Clifton NY, US
David Roger Moore - Rexford NY, US
Paul Michael Smigelski - Glenville NY, US
John Thomas Connelly - Seattle WA, US
Benjamin David Grant - Bellevue WA, US
Bernhard Hans Weigl - Seattle WA, US

International Classification:

G01N 33/493
C07K 1/22
B01D 15/08
G01N 33/50
G01N 33/569
B01D 63/02
A61B 10/00
C12M 1/26
G01N 33/558

Abstract:

A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.

US Patent:

20190187126, Jun 20, 2019

Filed:

Dec 20, 2017

Appl. No.:

15/848302

Inventors:

- Schenectady NY, US
- Bellevue WA, US
Cathryn Ellen OLSEN - Wilton NY, US
John Richard NELSON - Clifton Park NY, US
David Roger MOORE - Rexford NY, US
John Thomas CONNELLY - Seattle WA, US
Benjamin David GRANT - Bellevue WA, US
Bernhard Hans WEIGL - Seattle WA, US

International Classification:

G01N 33/493
C07K 1/22
B01D 15/08
G01N 33/50
G01N 33/569
B01D 63/02
C12M 1/26
A61B 10/00

Abstract:

A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.

US Patent:

20180322229, Nov 8, 2018

Filed:

Oct 30, 2017

Appl. No.:

15/797652

Inventors:

- Redwood Shores CA, US
Kendra Mariko Chen - Shoreline WA, US
Hyunjung Lee - Santa Clara CA, US
John Patrick Connelly - Santa Cruz CA, US
Vernon W. Hui - Bellevue WA, US
Sanjeev Khodaskar - Sunnyvale CA, US
Jeevan Gheevarghese Joseph - Dublin CA, US
Matthew P. Abrams - Las Cruces NM, US

Assignee:

Oracle International Corporation - Redwood Shores CA

International Classification:

G06F 17/50
H04L 29/06

Abstract:

Techniques are provided to quickly process stored objects to generate an accurate estimate of the number of live objects that will be responsive to a client's filtering request defined at least in part based on a filtering parameter. Stored objects generated from user interactions with webpages are modified to simulate live objects and processed by a live object-intake simulator. The simulated results are then filtered using the filtering parameter to form a subset of matching objects. An estimate of the number of live objects produced by the filtering parameter is generated using at least the count of the objects in the subset. A confidence metric of the estimate is computed, in some cases using a statistical model. Under certain conditions, the estimate is delivered, the confidence metric is delivered, and/or live object intake based on the filtering parameter is initiated.

US Patent:

20180290080, Oct 11, 2018

Filed:

Mar 29, 2018

Appl. No.:

15/939756

Inventors:

- Bellevue WA, US
John Thomas Connelly - Seattle WA, US
Benjamin David Grant - Bellevue WA, US
Stephen Paul Harston - Bothell WA, US
Isaac Santos - Seatac WA, US
Benjamin K. Wilson - Snoqualmie WA, US
Ozgur Emek Yildirim - Bellevue WA, US

International Classification:

B01D 29/90
G01N 1/40
B01L 3/02
B01L 9/00
B01L 3/00
B01D 29/05
B05C 17/01

Abstract:

A device for application of even pressure on a plunger head includes: a center rod with a pressure plate affixed at a first end and a back plate positioned adjacent to a second end; a positioning spring adjacent to the pressure plate at a surface distal to the center rod; a positioning plate adjacent to an end of the positioning spring distal to the pressure plate; a housing including an aperture at a position adjacent to a distal surface of the positioning plate; a main spring surrounding the center rod between the back plate and the pressure plate; and a mechanism positioned to move the center rod between the pressure plate and the back plate, the mechanism positioned to compress the main spring between the pressure plate and the back plate in response to force applied by a user.