John W Francis

US Patent:

8293493, Oct 23, 2012

Filed:

Jan 27, 2010

Appl. No.:

12/694318

Inventors:

Enriqueta Coll - Orlando FL, US
John Francis - Longwood FL, US

Assignee:

Adventist Health System/Sunbelt, Inc. - Orlando FL

International Classification:

C12Q 1/56

US Classification:

435 13, 436 69

Abstract:

A method for measuring a generation of thrombin in a sample of whole blood as a function of time includes adding to a sample of whole blood a fluorogenic substrate and a thrombin activator to form an activated sample. A conversion product is permitted to form in the activated sample. Fluorescence is measured as a function of time from a fluorescent group that is released during the formation of the conversion product with the use of a fluorescence detector. The fluorescence detector operates in an extended range mode and has an increased sensitivity. Thrombin generation as a function of time can then be calculated from the measured fluorescence as a function of time.

US Patent:

20210303930, Sep 30, 2021

Filed:

Mar 31, 2020

Appl. No.:

16/836106

Inventors:

- Armonk NY, US
- Los Angeles CA, US
John Paul Francis - Los Angeles CA, US

International Classification:

G06K 9/62
G06N 3/08
G06N 3/04

Abstract:

Methods and systems for training a model labeling two or more organic structures within an image. One method includes receiving a set of training images. The set of training images including a first plurality of images and a second plurality of images. Each of the first plurality of images including a label for each of the two or more organic structures and each of the second plurality of images including a label for only a subset of the two or more organic structures. The method further includes training the model using the first plurality of images, the second plurality of images, and a label merging function mapping a label from the first plurality of images to a label included in the second plurality of images.

US Patent:

20210303931, Sep 30, 2021

Filed:

Mar 31, 2020

Appl. No.:

16/836115

Inventors:

- Armonk NY, US
- Los Angeles CA, US
John Paul Francis - Los Angeles CA, US

International Classification:

G06K 9/62
G06T 7/00
G06N 3/08

Abstract:

Methods and systems for training a model labeling two or more organic structures in an image. One method includes receiving a set of training images including a first plurality of images and a second plurality of images. Each of the first plurality of images including a label for a first subset of the two or more organic structures and each of the second plurality of images including a label for a second subset of the two or more organic structures, the second subset being different than the first subset. The method also includes training the model using the first plurality of images, the second plurality of images, and a label merging function mapping a label included in the first plurality of images to a label included in the second plurality of images.