John D Gilbertson

US Patent:

20020089740, Jul 11, 2002

Filed:

Jan 11, 2001

Appl. No.:

09/757703

Inventors:

Arthur Wetzel - Murrysville PA, US
John Gilbertson - Pittsburgh PA, US
Jeffrey Beckstead - Valencia PA, US
Patricia Feineigle - Pittsburgh PA, US
Christopher Hauser - Pittsburgh PA, US
Frank Palmieri - Gibsonia PA, US

International Classification:

G02B021/06
G02B021/36
G02B023/00
G02B021/00

US Classification:

359/385000, 359/363000, 359/368000

Abstract:

An illumination system for microscopic digital montage imaging based on a pulsed light illumination source triggered by the position of a specimen with respect to the optical axis of the microscope. The strobe illumination is used to facilitate high-speed tiled (montage) image capture of otherwise static specimens with higher throughput and significantly reduced mechanical precision requirements and cost. The invention allows for perfectly aligned montage tiles at high throughputs using standard microscope optics, having camera frame rate be the limiting factor in microscopic tiled image capture.

US Patent:

20020090120, Jul 11, 2002

Filed:

Jan 11, 2001

Appl. No.:

09/758037

Inventors:

Arthur Wetzel - Murrysville PA, US
John Gilbertson - Pittsburgh PA, US
Jeffrey Beckstead - Valencia PA, US
Patricia Feineigle - Pittsburgh PA, US
Christopher Hauser - Pittsburgh PA, US
Frank Palmieri - Gibsonia PA, US

International Classification:

G06K009/00

US Classification:

382/128000

Abstract:

A system for processing a thumbnail image from a microscope slide to determine tissue locations on the slide. The system comprises an image cropping component, a tissue finding component, and a scan control component. The image cropping component crops the thumbnail image and removes portions of the image that fall outside of determined slide boundaries. The cropped image from the image cropping component is inputted into the tissue finding component. The tissue finding component identifies tissue regions by applying a sequence of filters that incorporate knowledge of typical appearance and location of tissue and non-tissue slide regions. The tissue finding component outputs a tiling matrix whose values indicate which tiles should be imaged. The scan control component interprets the tiling matrix and transposes positions of the tiling matrix into actual stage coordinate for a microscopic imaging.

US Patent:

20020114497, Aug 22, 2002

Filed:

Feb 21, 2001

Appl. No.:

09/788666

Inventors:

Arthur Wetzel - Murrysville PA, US
John Gilbertson - Pittsburgh PA, US
Jeffrey Beckstead - Valencia PA, US
Patricia Feineigle - Pittsburgh PA, US
Christopher Hauser - Pittsburgh PA, US
Frank Palmieri - Gibsonia PA, US

International Classification:

G06K009/00

US Classification:

382/128000

Abstract:

Today's technology allows montage images of large areas to be captured, stored and displayed at the resolution limit of the microscope optics. The invention reduces the overall time to capture a microscope slide by reducing the overhead associated with refocusing the optics at each tile location. Using a macroscopic image of the region to be scanned, representative focus positions are selected based on a predefined set of image characteristics. Prior to montage scanning, these focus positions are placed under the microscope optics and a best-focus position determined. A surface is fit to the resulting three-dimensional data. The parameters that define this surface are feed into the scanning control component to allow high-quality focused images to be acquired throughout the scanning process, eliminating the required stop, refocus, acquire image processing steps used in traditional montage imaging systems.

US Patent:

20060029266, Feb 9, 2006

Filed:

Sep 6, 2005

Appl. No.:

11/221331

Inventors:

Arthur Wetzel - Murrysville PA, US
John Gilbertson - Pittsburgh PA, US
Jeffrey Beckstead - Valencia PA, US
Patricia Feineigle - Pittsburgh PA, US
Christopher Hauser - Pittsburgh PA, US
Frank Palmieri - Gibsonia PA, US

International Classification:

G06K 9/00

US Classification:

382128000

Abstract:

A system for processing a thumbnail image from a microscope slide to determine tissue locations on the slide. The system comprises an image cropping component, a tissue finding component, and a scan control component. The image cropping component crops the thumbnail image and removes portions of the image that fall outside of determined slide boundaries. The cropped image from the image cropping component is inputted into the tissue finding component. The tissue finding component identifies tissue regions by applying a sequence of filters that incorporate knowledge of typical appearance and location of tissue and non-tissue slide regions. The tissue finding component outputs a tiling matrix whose values indicate which tiles should be imaged. The scan control component interprets the tiling matrix and transposes positions of the tiling matrix into actual stage coordinate for a microscopic imaging.

US Patent:

20060045320, Mar 2, 2006

Filed:

Oct 26, 2005

Appl. No.:

11/258803

Inventors:

Arthur Wetzel - Murrysville PA, US
John Gilbertson - Pittsburgh PA, US
Jeffrey Beckstead - Valencia PA, US
Patricia Feineigle - Pittsburgh PA, US
Christopher Hauser - Pittsburgh PA, US
Frank Palmieri - Gibsonia PA, US

International Classification:

G06K 9/00

US Classification:

382128000

Abstract:

Imaging apparatuses and methods that capture a low-resolution image of a slide, identify a region of interest, and capture a high-resolution image of the region of interest.

US Patent:

20060204072, Sep 14, 2006

Filed:

May 9, 2006

Appl. No.:

11/430721

Inventors:

Arthur Wetzel - Murrysville PA, US
John Gilbertson - Pittsburgh PA, US
Jeffrey Beckstead - Valencia PA, US
Patricia Feineigle - Pittsburgh PA, US
Christopher Hauser - Pittsburgh PA, US
Frank Palmieri - Gibsonia PA, US

International Classification:

G06K 9/00

US Classification:

382133000

Abstract:

An imaging apparatus. The imaging apparatus may find an area in which a specimen is present, then focus on the specimen and capture images of the specimen during continuous stage motion.

US Patent:

20080123919, May 29, 2008

Filed:

Oct 31, 2007

Appl. No.:

11/981774

Inventors:

Arthur W. Wetzel - Murrysville PA, US
John R. Gilbertson - Pittsburgh PA, US
Jeffrey A. Beckstead - Valencia PA, US
Patricia A. Feineigle - Pittsburgh PA, US
Christopher R. Hauser - Pittsburgh PA, US
Frank A. Palmieri - Gibsonia PA, US

International Classification:

G06K 9/00

US Classification:

382128

Abstract:

A system for determining tissue locations on a slide.

US Patent:

43406289, Jul 20, 1982

Filed:

Nov 26, 1979

Appl. No.:

6/097405

Inventors:

John R. Gilbertson - Pittsburgh PA
Richard J. Crout - Monroeville PA

International Classification:

A61K 716
A61K 31045

US Classification:

424 49

Abstract:

A method of inhibiting growth of bacteria comprising exposing the bacteria to an effective concentration of a polyunsaturated long-chain alcohol selected from the group consisting of linolenyl alcohol and linoleyl alcohol. The bacteria may be selected from the group consisting of Clostridium butyricum, Clostridium perfringens, Streptococcus mutans, Streptococcus mutans BHT and Streptococcus sanguis. A bactericidal product comprising an orally administerable product. The orally administerable product contains an effective concentration of antibacterial compound selected from the group consisting of linolenyl alcohol and linoleyl alcohol to produce an orally administerable product which will resist growth of bacteria selected from the group consisting of Clostridium butyricum, Clostridium perfringens, Streptococcus mutans, Streptococcus mutans BHT and Streptococcus sanguis.

Address:

3235 Fernbrook Ln N, Minneapolis, MN 55447

VIN:

1GCHK23D27F131297

Make:

CHEVROLET

Model:

SILVERADO 2500HD CLASSIC

Year:

2007