John D Helm

US Patent:

46345477, Jan 6, 1987

Filed:

Nov 8, 1985

Appl. No.:

6/796430

Inventors:

Richard M. Boden - Ocean NJ
John R. Helm - East Keansburg NJ

Assignee:

International Flavors & Fragrances Inc. - New York NY

International Classification:

A61K 746

US Classification:

252522R

Abstract:

Described are oxobicyclononane derivatives and mixtures of same having the generic structure: ##STR1## wherein X, Y, X' and Y' each represents the moiety having one of the structures: ##STR2## wherein one of the dashed lines represents a carbon-carbon single bond and the other of the dashed lines represents a carbon-carbon double bond with the proviso that when X' and Y' are each the moiety: ##STR3## then the dashed line at the "2-3" position is a carbon-carbon double bond and the dashed line at the "6-7" position is a carbon-carbon single bond and one of X or Y has the structure: ##STR4## and the other of X or Y has the structure: ##STR5## and with the further proviso that when X and Y are the moieties: ##STR6## then the dashed line at the "6-7" position is a carbon-carbon double bond and the dashed line at the "2-3" position is a carbon-carbon single bond and one of X' or Y' has the structure: ##STR7## and the other of X' or Y' has the structure: ##STR8## and wherein R represents hydrogen, C. sub. 1 -C. sub. 3 acyl or C. sub. 1 -C. sub. 2 alkoxy carbonyl with the major portion of the mixtures defined according to the generic structure: ##STR9## wherein one of X or Y is the moiety: ##STR10## and the other of X or Y is the moiety: ##STR11## with R being one of hydrogen, C. sub. 1 -C. sub.

US Patent:

46081941, Aug 26, 1986

Filed:

Aug 8, 1985

Appl. No.:

6/763569

Inventors:

Richard M. Boden - Ocean NJ
John R. Helm - East Keansburg NJ

Assignee:

International Flavors & Fragrances Inc. - New York NY

International Classification:

A61K 746

US Classification:

252522R

Abstract:

Described are oxobicyclononane derivatives having the generic structure: ##STR1## wherein R represents methyl or ethyl; wherein one of the dashed lines represents a carbon-carbon single bond or a carbon-carbon double bond; wherein N and P each represents 0 or 1 with the proviso that when N represents 1 the dashed line at the "2-3" position is a single bond with the sum of N and P being equal to 1 and uses thereof in augmenting or enhancing the aroma of perfume compositions, perfumed articles and colognes.

US Patent:

46735330, Jun 16, 1987

Filed:

Jun 27, 1986

Appl. No.:

6/879417

Inventors:

Richard M. Boden - Ocean NJ
John R. Helm - East Keansburg NJ

Assignee:

International Flavors & Fragrances Inc. - New York NY

International Classification:

A61K 746

US Classification:

252522R

Abstract:

Described are oxobicyclononane derivatives and mixtures of same having the generic structure: ##STR1## wherein X, Y, X' and Y' each represents the moiety having one of the structures: ##STR2## wherein one of the dashed lines represents a carbon-carbon single bond and the other of the dashed lines represents a carbon-carbon double bond with the proviso that when X' and Y' are each the moiety: ##STR3## then the dashed line at the "2-3" position is a carbon-carbon double bond and the dashed line at the "6-7" position is a carbon-carbon single bond and one of X or Y has the structure: ##STR4## and the other of X or Y has the structure: ##STR5## and with the further proviso that when X and Y are the moieties: ##STR6## then the dashed line at the "6-7" position is a carbon-carbon double bond and the dashed line at the "2-3" position is a carbon-carbon single bond and one of X' or Y' has the structure: ##STR7## and the other of X' or Y' has the structure: ##STR8## and wherein R represents hydrogen, C. sub. 1 -C. sub. 3 acyl or C. sub. 1 -C. sub. 2 alkoxy carbonyl with the major portion of the mixtures defined according to the generic structure: ##STR9## wherein one of X or Y is the moiety: ##STR10## and the other of X or Y is the moiety: ##STR11## with R being one of hydrogen, C. sub. 1 -C. sub.