John George Hess

US Patent:

6407207, Jun 18, 2002

Filed:

Nov 8, 1993

Appl. No.:

08/148708

Inventors:

Joseph A. Borkowski - Montclair NJ
John W. Hess - Westfield NJ
Catherine D. Strader - Verona NJ
Richard W. Ransom - New Britain PA

Assignee:

Merck Co., Inc. - Rahway NJ

International Classification:

C07K 14705

US Classification:

530350, 435 691, 536 235

Abstract:

The present invention is a cloned human BK-2 bradykinin receptor cloned from a human lung fibroblast cell line. A cDNA clone, also part of the instant invention, encodes a novel 364 amino acid protein (the BK-2 receptor) that has the characteristics of a seven transmembrane domain G-protein coupled receptor. The invention is used to express a BK-2 bradykinin receptor in a host mammalian cell to screen for pharmaceutical antagonists or agonists which bind to or interact with the BK-2 bradykinin receptor protein.

US Patent:

20020169697, Nov 14, 2002

Filed:

Feb 20, 2002

Appl. No.:

10/081924

Inventors:

Joshua Hicks - Kennesaw GA, US
Mark Scoretz - Kennesaw GA, US
Daniel Barnard - Marietta GA, US
John Hess - Marietta GA, US

International Classification:

G06F017/60

US Classification:

705/028000

Abstract:

Legacy parts information for steam turbines is made accessible via a database which employs hierarchical parts groupings, distribution codes, categories, and plain language parts titles and/or descriptions. In one embodiment, the invention provides a process for receiving legacy parts information and modifying the legacy parts information to create the computer searchable database in a fashion which facilitates easier searching.

US Patent:

20030036633, Feb 20, 2003

Filed:

Oct 22, 2001

Appl. No.:

10/007343

Inventors:

David Linemeyer - Westfield NJ, US
John Hess - Westfield NJ, US
Joseph Borkowski - Westfield NJ, US
Kathleen Bierilo - Matawan NJ, US
John Menke - Morganville NJ, US

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

C07K014/705
C12P021/02
C12N005/06
C07H021/04

US Classification:

530/350000, 536/023500, 435/069100, 435/325000, 435/320100

Abstract:

DNAs encoding bradykinin Breceptors from mammalian cells have been cloned and characterized. The recombinant receptor is capable of forming receptors which bind des-Argkallidin and other B-specific ligands. The DNA has been expressed in recombinant host cells which produce active recombinant protein. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.

US Patent:

20090157748, Jun 18, 2009

Filed:

Dec 14, 2007

Appl. No.:

11/957171

Inventors:

John M. Hess - Alpharetta GA, US

Assignee:

MCKESSON FINANCIAL HOLDING LIMITED - Hamilton

International Classification:

G06F 7/00

US Classification:

7071041, 707E17009

Abstract:

The present invention provides for efficient random access to the contents of files encoded with two or more layers of standard or custom encoding. In accordance with an embodiment of the present invention, a file of transaction messages are encoded by dividing the file into multiple discretely-sized, blocks of data are independently encoded. When information in a certain transaction message within the unencoded file is requested, only the encoded block(s) containing that transaction message is decoded.

US Patent:

59345144, Aug 10, 1999

Filed:

Jul 10, 1998

Appl. No.:

9/113250

Inventors:

William H. Lampe - Marietta GA
Inocencio Martinez - Kennesaw GA
John F. Kaiser - Snellville GA
John M. Hess - Waukesha WI
Jeffrey T. Randall - Oconomowoc WI
Christopher J. Wood - Wauwatosa WI

Assignee:

AptarGroup, Inc. - Crystal Lake IL
The Coca-Cola Company - Atlanta GA

International Classification:

B67D 532

US Classification:

22215306

Abstract:

A dispensing valve closure (10) is provided which includes a closure body (12) and a cap (14). A self-sealing dispensing valve (16) is disposed within the closure (10) and is held in place with a retaining ring (18). An inner seal (20) is also placed within the closure (10) to allow for sealing on a package.

US Patent:

63070278, Oct 23, 2001

Filed:

May 10, 1999

Appl. No.:

9/307912

Inventors:

David L. Linemeyer - Westfield NJ
John W. Hess - Westfield NJ
Joseph A. Borkowski - Westfield NJ
Kathleen K. Bierilo - Matawan NJ
John G. Menke - Morganville NJ

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

C07K 1628

US Classification:

53038822

Abstract:

DNAs encoding bradykinin B. sub. 1 receptors from mammalian cells have been cloned and characterized. The recombinant receptor is capable of forming receptors which bind desArg. sup. 10 kallidin and other B. sub. 1 -specific ligands. The DNA has been expressed in recombinant host cells which produce active recombinant protein. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.

US Patent:

57508267, May 12, 1998

Filed:

Dec 2, 1996

Appl. No.:

8/759848

Inventors:

Joseph A. Borkowski - Westfield NJ
Howard Y. Chen - Westfield NJ
John W. Hess - Westfield NJ
Catherine D. Strader - Verona NJ
Myrna E. Trumbauer - Yardley PA

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

A61K 4900
C12N 1500
C12N 1509

US Classification:

800 2

Abstract:

A transgenic non-human animal with alterations in a bradykinin B2 receptor gene is prepared by introduction of a gene encoding an altered bradykinin B2 receptor into a host non-human animal.

US Patent:

59345128, Aug 10, 1999

Filed:

Apr 9, 1997

Appl. No.:

8/833774

Inventors:

William H. Lampe - Marietta GA
Inocencio Martinez - Kennesaw GA
John F. Kaiser - Snellville GA
John M. Hess - Waukesha WI
Jeffrey T. Randall - Oconomowoc WI
Christopher J. Wood - Wauwatosa WI
Jon K. Plotkin - Powder Springs GA

Assignee:

The Coca-Cola Company - Atlanta GA
Aptar Group, Inc. - Crystal Lake IL

International Classification:

B67D 532

US Classification:

222108

Abstract:

A dispensing valve closure (10) is provided which includes a closure body (12) and a cap (14). A self-sealing dispensing valve (16) is disposed within the closure (10) and is held in place with a retaining ring (18). Drain holes (50-56) allow drainage of any fluids built up under the cap (14).

Address:

1287 Cloudstone Ct, Grove City, OH 43123

Phone:

(614)5391324

VIN:

1ZVHT85H175235069

Make:

FORD

Model:

MUSTANG

Year:

2007