John P. Grace - Lake Villa IL Neil W. Loomis - Racine WI Thomas G. Schapira - Bristol WI Sie Ting Wong - Mundelein IL Kristin M. Noonan - Chicago IL Michael G. Lowery - Wildwood IL Pete M. Bojan - Grayslake IL Daniel P. Schmidt - Bannockburn IL Tung-Ming Huang - Buffalo Grove IL Robert G. Hiltibran - late of Libertyville IL Mark R. Pope - Grayslake IL John J. Kotlarik - Lake Geneva WI Brian Joseph Tarkowski - Lake Villa IL David Dean Cunningham - Lake Villa IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61B 500
US Classification:
600573, 604317
Abstract:
The present invention involves apparatus and methods for use in collecting bodily fluids, such as interstitial fluids, from the epidermal layer of an animal. A preferred apparatus includes a pressure head and, optionally, a holder therefor for supplying a positive pressure to the head. The methods include the application of a positive pressure to the area surrounding an epidermal site from which stratum corneum has been breached, such as by laser ablation, to cause bodily fluids, such as interstitial fluids, to exude from the site and collecting the fluids exuding therefrom.
James H. Lipscomb - Kennett Square PA Larry Jurik - late of Elmhurst IL Bernard Katz - Rockaway NJ Michael J. Keating - Blairstown NJ Stone Klengler - Escondido CA John J. Kotlarik - Lake Geneva WI Mieczyslaw Wroblewski - Lake Forest IL
Assignee:
Gen-Probe, Inc. - San Diego CA
International Classification:
G01F 15075
US Classification:
702 47, 7386142, 7386144, 138104, 324647, 417 63
Abstract:
A sensor for detecting contact of a fluid delivery probe with a fluid surface and for detecting fluid flow through the probe includes a first electrode disposed along a fluid flow path of the probe upstream from a distal tip of the probe and a second electrode longitudinally spaced and electrically isolated from the first electrode and disposed at the distal tip of the probe. An oscillating signal is transmitted through the first electrode, and at least a portion of the signal is received through the second electrode. Through changes in the received signal due to the distal tip of the probe coming into contact with a fluid surface or due to fluid flow through the conduit between the first and second electrodes, fluid surface contact and fluid flow can be detected. A pressure sensor can be employed to monitor internal fluid pressure within the fluid conduit of the fluid delivery probe as a secondary, redundant mechanism for detecting fluid flow through the conduit.
James H. Lipscomb - Kennett Square PA Larry Jurik - late of Elmhurst IL Bernard Katz - Rockaway NJ Michael J. Keating - Blairstown NJ Stone Klengler - Escondido CA John J. Kotlarik - Lake Geneva WI Mieczyslaw Wroblewski - Lake Forest IL
Assignee:
Gen-Probe Incorporated - San Diego CA
International Classification:
G01F 2202
US Classification:
7386142, 7386144, 702 47
Abstract:
A sensor for detecting contact of a fluid delivery probe with a fluid surface and for detecting fluid flow through the probe includes a first electrode disposed along a fluid flow path of the probe upstream from a distal tip of the probe and a second electrode longitudinally spaced and electrically isolated from the first electrode and disposed at the distal tip of the probe. An oscillating signal is transmitted through the first electrode, and at least a portion of the signal is received through the second electrode. Through changes in the received signal due to the distal tip of the probe coming into contact with a fluid surface or due to fluid flow through the conduit between the first and second electrodes, fluid surface contact and fluid flow can be detected. A pressure sensor can be employed to monitor internal fluid pressure within the fluid conduit of the fluid delivery probe as a secondary, redundant device for detecting fluid flow through the conduit.
James H. Lipscomb - Kennett Square PA Larry Jurik - late of Elmhurst IL Bernard Katz - Rockaway NJ Michael J. Keating - Blairstown NJ Stone Klengler - Escondido CA John J. Kotlarik - Lake Geneva WI Mieczyslaw Wroblewski - Lake Forest IL
Assignee:
Gen-Probe Incorporated - San Diego CA
International Classification:
G01F 2202
US Classification:
417 63, 7386422, 7386425
Abstract:
A sensor for detecting contact of a fluid delivery probe with a fluid surface and for detecting fluid flow through the probe includes a first electrode disposed along a fluid flow path of the probe upstream from a distal tip of the probe and a second electrode longitudinally spaced and electrically isolated from the first electrode and disposed at the distal tip of the probe. An oscillating signal is transmitted through the first electrode, and at least a portion of the signal is received through the second electrode. Through changes in the received signal due to the distal tip of the probe coming into contact with a fluid surface or due to fluid flow through the conduit between the first and second electrodes, fluid surface contact and fluid flow can be detected. A pressure sensor can be employed to monitor internal fluid pressure within the fluid conduit of the fluid delivery probe as a secondary, redundant mechanism for detecting fluid flow through the conduit.
Apparatus And Method For The Collection Of Interstitial Fluids
John P. Grace - Lake Villa IL Neil W. Loomis - Racine WI Thomas G. Schapira - Bristol WI Sie Ting Wong - Mundelein IL Kristin M. Noonan - Chicago IL Michael G. Lowery - Wildwood IL Pete M. Bojan - Grayslake IL Daniel P. Schmidt - Bannockburn IL Tung-Ming Huang - Buffalo Grove IL Robert G. Hiltibran - late of Libertyville IL Mark R. Pope - Grayslake IL John J. Kotlarik - Lake Geneva WI Brian Joseph Tarkowski - Lake Villa IL David Dean Cunningham - Lake Villa IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61B 1000
US Classification:
600573
Abstract:
The present invention involves apparatus and methods for use in collecting bodily fluids, such as interstitial fluids, from the epidermal layer of an animal. A preferred apparatus includes a pressure head and, optionally, a holder therefor for supplying a positive pressure to the head. The methods include the application of a positive pressure to the area surrounding an epidermal site from which stratum corneum has been breached, such as by laser ablation, to cause bodily fluids, such as interstitial fluids, to exude from the site and collecting the fluids exuding therefrom.
James H. Lipscomb - Kennett Square PA, US Anna Jurik - Elmhurst IL, US Bernard Katz - Rockaway NJ, US Michael J. Keating - Blairstown NJ, US Stone Klengler - Escondido CA, US John J. Kotlarik - Lake Geneva WI, US Mieczyslaw Wroblewski - Lake Forest IL, US
Assignee:
Gen-Probe Incorporated - San Diego CA
International Classification:
F16L055/00 F16L009/22 G01F001/56 B01L003/02
US Classification:
138104, 137557, 138177, 7386473, 7386425, 324647
Abstract:
A sensor for detecting contact of a fluid delivery probe with a fluid surface and for detecting fluid flow through the probe includes a first electrode disposed along a fluid flow path of the probe upstream from a distal tip of the probe and a second electrode longitudinally spaced and electrically isolated from the first electrode and disposed at the distal tip of the probe. An oscillating signal is transmitted through the first electrode, and at least a portion of the signal is received through the second electrode. Through changes in the received signal due to the distal tip of the probe coming into contact with a fluid surface or due to fluid flow through the conduit between the first and second electrodes, fluid surface contact and fluid flow can be detected. A pressure sensor can be employed to monitor internal fluid pressure within the fluid conduit of the fluid delivery probe as a secondary, redundant mechanism for detecting fluid flow through the conduit.
James H. Lipscomb - Kennett Square PA, US Anna Jurik - Elmhurst IL, US Bernard Katz - Rockaway NJ, US Michael J. Keating - Blairstown NJ, US Stone Klengler - Escondido CA, US John J. Kotlarik - Lake Geneva WI, US Mieczyslaw Wroblewski - Lake Forest IL, US
Assignee:
Gen-Probe Incorporated - San Diego CA
International Classification:
G01F023/284
US Classification:
342124, 324647, 73290 R
Abstract:
A sensor for detecting contact of a fluid delivery probe with a fluid surface and for detecting fluid flow through the probe includes a first electrode disposed along a fluid flow path of the probe upstream from a distal tip of the probe and a second electrode longitudinally spaced and electrically isolated from the first electrode and disposed at the distal tip of the probe. An oscillating signal is transmitted through the first electrode, and at least a portion of the signal is received through the second electrode. Through changes in the received signal due to the distal tip of the probe coming into contact with a fluid surface or due to fluid flow through the conduit between the first and second electrodes, fluid surface contact and fluid flow can be detected. A pressure sensor can be employed to monitor internal fluid pressure within the fluid conduit of the fluid delivery probe as a secondary, redundant mechanism for detecting fluid flow through the conduit.
David A. Myus - Green Bay WI, US John J. Kotlarik - Green Bay WI, US
Assignee:
BAY TEK GAMES, INC. - Pulaski WI
International Classification:
A63F 13/06
US Classification:
463 23
Abstract:
A system and method for operating a game of skill to provide awards or prizes to players of the game when the player has been successful in completing the game task. The game of skill is operated at a current skill level and the game monitors a rule parameter, such as a winning percentage or payout percentage, as the game is played. If the rule parameter exceeds a maximum limit, the difficulty level of the game is adjusted. Likewise, if the rule parameter is below a minimum limit, the difficulty level of the game is decreased. At each and every difficulty level, the player is able to succeed in winning the game of skill.