John Z Lu

US Patent:

7601107, Oct 13, 2009

Filed:

Mar 17, 2006

Appl. No.:

11/378704

Inventors:

Tate Maloy - Los Angeles CA, US
John Lu - San Francisco CA, US

International Classification:

A63B 21/02

US Classification:

482123, 482 34, 482126, 482146, 482 79

Abstract:

A training and/or exercise device and method for exercising muscle groups of the entire body is disclosed herein that is portable, easy to use, can work the muscles of the entire body, and does not have complicated integrating parts when in use. The device and method allows a free range of motion about a vertical axis without substantial resistance. The device allows a wide variety of movement using a single device, and particularly allows for balancing movements that are advantageous for strengthening the core. Further, the training device is particularly advantageous for use in a home gym and may be stored under a bed or within the overhead compartment of an airplane.

US Patent:

7658700, Feb 9, 2010

Filed:

Aug 9, 2004

Appl. No.:

10/915126

Inventors:

Tate Maloy - Los Angeles CA, US
John Lu - San Francisco CA, US

International Classification:

A63B 22/16
A63B 21/055
A63B 21/068

US Classification:

482132, 482 95, 482123, 482141, 482146, 273449

Abstract:

A training and/or exercise device and method for exercising muscle groups of the entire body is disclosed herein that is portable, easy to use, can work the muscles of the entire body, and does not have complicated integrating parts when in use. The device and method allows a free range of motion about a vertical axis without substantial resistance. The device allows a wide variety of movement using a single device, and particularly allows for balancing movements that are advantageous for strengthening the core. Further, the training device is particularly advantageous for use in a home gym and may be stored under a bed or within the overhead compartment of an airplane.

US Patent:

8501678, Aug 6, 2013

Filed:

Dec 19, 2011

Appl. No.:

13/329897

Inventors:

Jeonghoon Sun - Thousand Oaks CA, US
Hui-Quan Han - Thousand Oaks CA, US
Keith Soo-Nyung Kwak - Thousand Oaks CA, US
Xiaolan Zhou - Thousand Oaks CA, US
John Lu - Culver City CA, US

Assignee:

Atara Biotherapeutics, Inc. - Brisbane CA

International Classification:

A61K 38/00
A61P 35/00

US Classification:

514 11, 514 193

Abstract:

The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.

US Patent:

20070149458, Jun 28, 2007

Filed:

Dec 6, 2006

Appl. No.:

11/635731

Inventors:

Hq Han - Thousand Oaks CA, US
Alexander DePaoli - Santa Barbara CA, US
John Lu - Culver City CA, US
Jin Wang - Moorpark CA, US

Assignee:

Amgen Inc. - Thousand Oaks CA

International Classification:

A61K 38/10

US Classification:

514015000

Abstract:

The present invention provides methods for treating disorders arising from hypogonadism, rheumatoid cachexia, cachexia due to burns, cachexia due to administration of chemical agents, cachexia due to diabetes, diabetic nephropathy, Prader Willi syndrome, excessive TNF-α, and other muscle-related, metabolic and inflammatory disorders by administering myostatin antagonists to subjects suffering from such disorders.

US Patent:

20110008375, Jan 13, 2011

Filed:

Sep 27, 2010

Appl. No.:

12/891741

Inventors:

HAN HQ - THOUSAND OAKS CA, US
ALEXANDER DEPAOLI - SANTA BARBARA CA, US
JOHN ZHAO-NIAN LU - CULVER CITY CA, US
JIN LIN WANG - MOORPARK CA, US

International Classification:

A61K 39/395
A61K 38/10
A61K 38/16
A61P 21/00

US Classification:

4241791, 514 89

Abstract:

The present invention provides methods for treating disorders arising from hypogonadism, rheumatoid cachexia, cachexia due to burns, cachexia due to administration of chemical agents, cachexia due to diabetes, diabetic nephropathy, Prader Willi syndrome, excessive TNF-α, and other muscle-related, metabolic and inflammatory disorders by administering myostatin antagonists to subjects suffering from such disorders.

US Patent:

20130288983, Oct 31, 2013

Filed:

Jul 1, 2013

Appl. No.:

13/932421

Inventors:

Huiquan Han - Thousand Oaks CA, US
Keith Soo-Nyung Kwak - Thousand Oaks CA, US
Xiaolan Zhou - Thousand Oaks CA, US
John Lu - Culver City CA, US

International Classification:

C07K 14/705
A61K 31/655
A61K 38/17
A61K 31/513

US Classification:

514 193

Abstract:

The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.

US Patent:

20200108085, Apr 9, 2020

Filed:

Dec 13, 2019

Appl. No.:

16/714407

Inventors:

- Thousand Oaks CA, US
- South San Francisco CA, US
Isaac CIECHANOVER - Burlingame CA, US
Xiaolan ZHOU - Newbury Park CA, US
John Zhao-Nian LU - Alhambra CA, US

International Classification:

A61K 31/704
A61K 45/06
A61K 31/7068
C07K 16/22
A61K 38/17
A61K 39/395

Abstract:

The present invention relates to methods of treating ovarian cancer in a subject by administering to the subject by evaluating the subject's expression levels of specific biomarkers or angiogenic an anti-activin-A compound, such as an anti-activin-A antibody or an activin-A-binding receptor. In some embodiments, at least two compounds are administered to the subject, where the first compound is an anti-activin A compound, and the second compound is a chemotherapeutic compound, for example capecitabine. The invention further relates to methods of identifying subjects for treatment factors.

US Patent:

20150359850, Dec 17, 2015

Filed:

Feb 3, 2014

Appl. No.:

14/764288

Inventors:

- South San Francisco CA, US
- Thousand Oaks CA, US
Isaac Ciechanover - Burlingame CA, US
Xiaolan Zhou - Newbury Park CA, US
John Zhao-Nian Lu - Culver City CA, US

Assignee:

SANTA MARIA BIOTHERAPEUTICS, INC. - South San Francisco CA
AMGEN INC. - Thousand Oaks CA

International Classification:

A61K 38/17
A61K 31/704
C07K 16/22
A61K 31/7068
A61K 45/06
A61K 39/395

Abstract:

The present invention relates to methods of treating ovarian cancer in a subject by administering to the subject by evaluating the subject's expression levels of specific biomarkers or angiogenic an anti-activin-A compound, such as an anti-activin-A antibody or an activin-A-binding receptor. In some embodiments, at least two compounds are administered to the subject, where the first compound is an anti-activin A compound, and the second compound is a chemotherapeutic compound, for example capecitabine. The invention further relates to methods of identifying subjects for treatment factors.

Address:

2102 Glendon Ave, Los Angeles, CA 90025

VIN:

JTHBL46F275020068

Make:

LEXUS

Model:

LS 460

Year:

2007