John W Mcghee

US Patent:

20050143965, Jun 30, 2005

Filed:

Aug 2, 2004

Appl. No.:

10/910239

Inventors:

Gregory Failla - Gig Harbor WA, US
John McGhee - Los Alamos NM, US
Todd Warcing - Gig Harbor WA, US
Douglas Busnett - Pattersonville NY, US

International Classification:

G06F017/10

US Classification:

703002000

Abstract:

Various embodiments of the present invention provide methods and systems for deterministic calculation of radiation doses, delivered to specified volumes within human tissues and organs, and specified areas within other organisms, by external and internal radiation sources. Embodiments of the present invention provide for creating and optimizing computational mesh structures for deterministic radiation transport methods. In general these approaches seek to both improve solution accuracy and computational efficiency. Embodiments of the present invention provide methods for planning radiation treatments using deterministic methods. The methods of the present invention may also be applied for dose calculations, dose verification, and dose reconstruction for many different forms of radiotherapy treatments, including: conventional beam therapies, intensity modulated radiation therapy (“IMRT”), proton, electron and other charged particle beam therapies, targeted radionuclide therapies, brachytherapy, stereotactic radiosurgery (“SRS”), Tomotherapy; and other radiotherapy delivery modes. The methods may also be applied to radiation-dose calculations based on radiation sources that include linear accelerators, various delivery devices, field shaping components, such as jaws, blocks, flattening filters, and multi-leaf collimators, and to many other radiation-related problems, including radiation shielding, detector design and characterization; thermal or infrared radiation, optical tomography, photon migration, and other problems.

US Patent:

20060259282, Nov 16, 2006

Filed:

Nov 14, 2005

Appl. No.:

11/273596

Inventors:

Gregory Failla - Gig Harbor WA, US
John McGhee - Hollis NH, US
Todd Wareing - Gig Harbor WA, US
Douglas Barnett - Pattersonville NY, US

International Classification:

G06F 17/10
G06F 7/60

US Classification:

703002000

Abstract:

One method embodiment of the present invention is a process for using deterministic methods to calculate dose distributions resulting from radiotherapy treatments, diagnostic imaging, or industrial sterilization, and for calculating scatter corrections used for image reconstruction. In one embodiment of the present invention, the method provides a means for constructing a deterministic computational grid from an acquired 3-D image representation, transport of an external radiation source through field shaping devices and into the computational grid, calculation of the radiation scatter and/or delivered dose in the computational grid, and subsequent transport of the scattered radiation to detectors external to the computational grid. In another embodiment of the present invention, the method includes a process, by solving the adjoint form of the transport equation, which can enable patient dose responses to be calculated independently of treatment parameters and prior to treatment planning, enabling patient dose fields to be accurately reconstructed during treatment planning and verification.

US Patent:

20080004845, Jan 3, 2008

Filed:

Jun 1, 2007

Appl. No.:

11/809774

Inventors:

Gregory Failla - Gig Harbor WA, US
Todd Wareing - Gig Harbor WA, US
John McGhee - Hollis NH, US
Douglas Barnett - Pattersonville NY, US

International Classification:

A61B 5/00

US Classification:

703002000

Abstract:

Method and system that allows patient dose response functions to be calculated, prior to treatment planning, for external photon beam radiotherapy. In one embodiment, for each location where a separate dose value is desired, referred to as a dose region, adjoint calculations are performed to calculate the adjoint solution fields associated with that dose region. Once potential beam directions are specified, a ray tracing process is performed to transport the adjoint solution fields out of the patient and to locations where treatment plan parameters may be specified. The output of this process is the dose response at each dose region resulting from a prescribed photon fluence, at a given location, direction, and energy.

US Patent:

20080091388, Apr 17, 2008

Filed:

Mar 21, 2007

Appl. No.:

11/726386

Inventors:

Gregory Failla - Gig Harbor WA, US
John McGhee - Hollis NH, US
Todd Wareing - Gig Harbor WA, US
Douglas Barnett - Patersonville NY, US

International Classification:

G06F 17/10

US Classification:

703002000

Abstract:

Various embodiments of the present invention provide processes for applying deterministic radiation transport solution methods for calculating doses and predicting scatter in radiotherapy and imaging applications. One method embodiment of the present invention is a process for using deterministic methods to calculate dose distributions resulting from radiotherapy treatments, diagnostic imaging, or industrial sterilization, and for calculating image scatter for the purposes of image reconstruction. In one embodiment of the present invention, a method provides a means for transport of external radiation sources through field-shaping devices. In another embodiment of the present invention, a method includes a process for calculating the dose response at selected points and volumes prior to radiotherapy treatment planning.

US Patent:

20090063110, Mar 5, 2009

Filed:

Oct 28, 2008

Appl. No.:

12/290201

Inventors:

Gregory Alexander Failla - Gig Harbor WA, US
Douglas Allen Barnett - Pattersonville NY, US
John Morton McGhee - Hollis NH, US
Todd Arlin Wareing - Gig Harbor WA, US

Assignee:

Transpire,Inc. - Gig Harbor WA

International Classification:

G06G 7/48

US Classification:

703 2

Abstract:

Brachytherapy dose attributable to a brachytherapy source is computed for portions of a patient treatment volume corresponding to a pathological target volume and critical structures. Patient image data is accessed to derive a material voxel array. Multiple computation grids are derived. Primary particle fluence is computed for each first grid element using a ray tracing process from which a primary dose and a first scattered particle source are derived. Scattered particle fluence of the first scattered particle source is derived for each second grid element from which a secondary dose is derived. Each first grid element corresponds to a plurality of second grid elements. Primary dose and scattered dose combine to provide total dose at specific volumes. Brachytherapy source models and non-anatomical body surface models may be applied as applicable.