John W Morlan

US Patent:

20110111409, May 12, 2011

Filed:

Nov 5, 2010

Appl. No.:

12/940981

Inventors:

Dominick Sinicropi - Woodside CA, US
John Morlan - Foster City CA, US

International Classification:

C12Q 1/68
C12P 19/34
C07H 21/04
C12N 9/22

US Classification:

435 6, 435 915, 536 2431, 435199

Abstract:

The invention relates to methods of depleting RNA from a nucleic acid sample. The RNA may be any RNA, including, but not limited to, rRNA, tRNA, and mRNA. The method is useful for depleting RNA from a nucleic acid sample obtained from a fixed paraffin-embedded tissue (FPET) sample. The method may also be used to prepare cDNA, in particular, a cDNA library for further analysis or manipulation.

US Patent:

20200263257, Aug 20, 2020

Filed:

Feb 7, 2020

Appl. No.:

16/784696

Inventors:

- Redwood City CA, US
Dominick SINICROPI - Woodside CA, US
Robert J. PELHAM - Belmont CA, US
Michael R. CRAGER - Menlo Park CA, US
Francois COLLIN - Berkeley CA, US
James C. STEPHANS - DECEASED, US
Mei-Lan LIU - San Mateo CA, US
John D. MORLAN - Hayward CA, US
Kunbin QU - Palo Alto CA, US

Assignee:

GENOMIC HEALTH, INC. - Redwood City CA

International Classification:

C12Q 1/6886
G01N 33/574
C12Q 1/686
G16B 20/00

Abstract:

The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.

US Patent:

20190256923, Aug 22, 2019

Filed:

Jan 17, 2019

Appl. No.:

16/250179

Inventors:

- Redwood City CA, US
Dominick SINICROPI - Woodside CA, US
Robert J. PELHAM - Belmont CA, US
Michael R. CRAGER - Menlo Park CA, US
Francois COLLIN - Berkeley CA, US
James C. STEPHANS - Redwood City CA, US
Mei-Lan LIU - San Mateo CA, US
John D. MORLAN - Hayward CA, US
Kunbin QU - Palo Alto CA, US

Assignee:

GENOMIC HEALTH, INC. - Redwood City CA

International Classification:

C12Q 1/6886
G16B 20/00
C12Q 1/686
G01N 33/574

Abstract:

The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.

US Patent:

20180208968, Jul 26, 2018

Filed:

Jan 10, 2018

Appl. No.:

15/866840

Inventors:

- Redwood City CA, US
John Morlan - Foster City CA, US

Assignee:

Genomic Health, Inc. - Redwood City CA

International Classification:

C12Q 1/6806
C12Q 1/6848
C12N 15/10

Abstract:

The invention relates to methods of depleting RNA from a nucleic acid sample. The RNA may be any RNA, including, but not limited to, rRNA, tRNA, and mRNA. The method is useful for depleting RNA from a nucleic acid sample obtained from a fixed paraffin-embedded tissue (FPET) sample. The method may also be used to prepare cDNA, in particular, a cDNA library for further analysis or manipulation.

US Patent:

20160222463, Aug 4, 2016

Filed:

Jan 29, 2016

Appl. No.:

15/011206

Inventors:

- Redwood City CA, US
Dominick S. SINICROPI - Woodside CA, US
Robert J. PELHAM - Belmont CA, US
Michael R. CRAGER - Menlo Park CA, US
Francois COLLIN - Berkeley CA, US
James C. STEPHANS - Redwood City CA, US
Mei-Lan LIU - San Mateo CA, US
John D. MORLAN - Hayward CA, US
Kunbin QU - Palo Alto CA, US

Assignee:

GENOMIC HEALTH, INC. - Redwood City CA

International Classification:

C12Q 1/68

Abstract:

The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient, The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.

US Patent:

20150299771, Oct 22, 2015

Filed:

Mar 11, 2015

Appl. No.:

14/644455

Inventors:

- Redwood City CA, US
John Morlan - Foster City CA, US

Assignee:

GENOMIC HEALTH, INC. - Redwood City CA

International Classification:

C12Q 1/68

Abstract:

The invention relates to methods of depleting RNA from a nucleic acid sample. The RNA may be any RNA, including, but not limited to, rRNA, tRNA, and mRNA. The method is useful for depleting RNA from a nucleic acid sample obtained from a fixed paraffin-embedded tissue (FPET) sample. The method may also be used to prepare cDNA, in particular, a cDNA library for further analysis or manipulation.

US Patent:

20140296085, Oct 2, 2014

Filed:

Nov 2, 2012

Appl. No.:

14/355642

Inventors:

- Redwood City CA, US
Dominick S. Sinicropi - Woodside CA, US
Robert J. Pelham - Belmont CA, US
Michael R. Crager - Menlo Park CA, US
Francois Collin - Berkeley CA, US
James C. Stephans - Redwood City CA, US
Mei-Lan Liu - San Mateo CA, US
John D. Morlan - Foster City CA, US
Kunbin Qu - Palo Alto CA, US

Assignee:

GENOMIC HEALTH, INC. - Redwood City CA

International Classification:

G06F 19/18
C12Q 1/68

US Classification:

506 8, 435 612, 702 19

Abstract:

The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient, The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.