John Caldwell Pruitt

US Patent:

7780879, Aug 24, 2010

Filed:

Dec 18, 2008

Appl. No.:

12/316993

Inventors:

John Dallas Pruitt - Suwanee GA, US
Lynn Cook Winterton - Alpharetta GA, US
Bernhard Seiferling - Goldbach, DE
Jüergen Vogt - Flueh, CH
Harald Bothe - Wiesbaden, DE

Assignee:

Novartis AG - Basel

International Classification:

B29D 11/00
G02B 1/12
B29C 35/08
B29C 33/60
C08J 5/00
A61K 6/083

US Classification:

264 136, 264496, 264300, 264319, 26433113, 264 26, 522 76

Abstract:

The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

US Patent:

8092724, Jan 10, 2012

Filed:

Jul 13, 2010

Appl. No.:

12/834979

Inventors:

John Dallas Pruitt - Suwanee GA, US
Lynn Cook Winterton - Alpharetta GA, US
Bernhard Seiferling - Goldbach, DE
Jüergen Vogt - Flueh, SE
Harald Bothe - Wiesbaden, DE

Assignee:

Novartis AG - Basel

International Classification:

B29D 1/00
G02B 1/12
B29C 35/08
B29C 33/60
C08J 5/00
A61K 6/083

US Classification:

264 136, 264496, 264300, 264319, 26433113, 264 26, 522 76

Abstract:

The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

US Patent:

8163206, Apr 24, 2012

Filed:

Jun 16, 2009

Appl. No.:

12/456364

Inventors:

Frank Chang - Suwanee GA, US
Jürgen Vogt - Flueh, CH
John Dallas Pruitt - Suwanee GA, US
Xinming Qian - Johns Creek GA, US
Dawn A. Smith - Duluth GA, US
Angelika Maria Domschke - Duluth GA, US
Troy Vernon Holland - Suwanee GA, US
Richard Charles Turek - Atlanta GA, US
Daqing Wu - Suwanee GA, US

Assignee:

Novartis AG - Basel

International Classification:

B29D 11/00

US Classification:

264 138, 264 1, 264 132

Abstract:

The invention provide a method for making silicone hydrogel based on the Lightstream Technology from a monomer mixture with a curing time of less than about 100 seconds. The present invention is also related to silicone hydrogel contact lenses made according to methods of the invention.

US Patent:

8409599, Apr 2, 2013

Filed:

Nov 2, 2010

Appl. No.:

12/917504

Inventors:

Daqing Wu - Suwanee GA, US
Xinming Qian - Johns Creek GA, US
John Dallas Pruitt - Suwanee GA, US

Assignee:

Novartis AG - Basel

International Classification:

A61C 8/00

US Classification:

424422

Abstract:

The invention provides a cost-effective method for applying a hydrophilic coating onto a silicone hydrogel contact lens based on Fenton chemistry. The hydrophilic coating is covalently attached onto the contact lens at room temperature without UV irradiation. The invention also provides silicone hydrogel contact lenses having a hydrophilic coating obtained according to the method of the invention.

US Patent:

8440735, May 14, 2013

Filed:

Jul 13, 2010

Appl. No.:

12/834998

Inventors:

John Dallas Pruitt - Suwanee GA, US
Lynn Cook Winterton - Alpharetta GA, US
Bernhard Seiferling - Goldbach, DE
Jüergen Vogt - Flueh, CH
Harald Bothe - Wiesbaden, DE

Assignee:

Novartis AG - Basel

International Classification:

C08F 2/46
C08F 290/06
C08J 3/28
G02B 1/06
G02B 1/04

US Classification:

522 76, 522 71, 522 74, 522 99, 522148, 522172, 523105, 523106, 523107

Abstract:

The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

US Patent:

8480227, Jul 9, 2013

Filed:

Jul 29, 2011

Appl. No.:

13/193653

Inventors:

Yongxing Qiu - Duluth GA, US
John Dallas Pruitt - Suwanee GA, US
Sibichen J. Thekveli - Alpharetta GA, US
Robert Carey Tucker - Suwanee GA, US
Jared Nelson - Buford GA, US

Assignee:

Novartis AG - Basel

International Classification:

G02C 7/00

US Classification:

35115933, 426 13, 427 21

Abstract:

The invention is related to a hydrated silicone hydrogel contact lens having a layered structural configuration: a lower water content silicone hydrogel core (or bulk material) completely covered with a layer of a higher water content hydrogel totally or substantially free of silicone. A hydrated silicone hydrogel contact lens of the invention possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort.

US Patent:

8529057, Sep 10, 2013

Filed:

Jul 29, 2011

Appl. No.:

13/193651

Inventors:

Yongxing Qiu - Duluth GA, US
Newton T. Samuel - Suwanee GA, US
John Dallas Pruitt - Suwanee GA, US
Chandana Kolluru - Suwanee GA, US
Arturo N. Medina - Suwanee GA, US
Lynn Cook Winterton - Alpharetta GA, US
Daqing Wu - Suwanee GA, US
Xinming Qian - Johns Creek GA, US
Jared Nelson - Buford GA, US

Assignee:

Novartis AG - Basel

International Classification:

G02C 7/00

US Classification:

35115933, 428 13, 427 21

Abstract:

The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40 C. to about 140 C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.

US Patent:

8557940, Oct 15, 2013

Filed:

Jul 29, 2011

Appl. No.:

13/193642

Inventors:

Frank Chang - Suwanee GA, US
Robert Scott - Alpharetta GA, US
Jinyu Huang - Suwanee GA, US
Arturo N. Medina - Suwanee GA, US
Dawn A. Smith - Cullman AL, US
Laura Ann Sanders - Decatur GA, US
John Dallas Pruitt - Suwanee GA, US

Assignee:

Novartis AG - Basel

International Classification:

C08F 30/08

US Classification:

526279, 351160 R

Abstract:

The present invention provides an amphiphilic polysiloxane prepolymer which comprises hydrophilic monomeric units derived from at least one hydrophilic vinylic monomer, polysiloxane crosslinking units derived from at least one polysiloxane crosslinker having at least two terminal ethylenically-unsaturated groups, dangling polysiloxane chains each of which is terminated with one ethylenically unsaturated group, and chain-transfer units derived from a chain transfer agent other than a RAFT agent. A prepolymer of the invention is suitable for making hydrogel contact lenses. The present invention is also related to hydrogel contact lenses made from an amphiphilic polysiloxane prepolymer of the invention and to processes for preparing an amphiphilic polysiloxane prepolymer of the invention and for making silicone hydrogel contact lenses.

Address:

132 Oak Trl, Belmont, NC 28012

VIN:

4T1BF3EK1BU589019

Make:

TOYOTA

Model:

CAMRY

Year:

2011