John M Starr

US Patent:

6485947, Nov 26, 2002

Filed:

May 19, 2000

Appl. No.:

09/574873

Inventors:

Vineet Rajgarhia - Minnetonka MN
Vassily Hatzimanikatis - Minneapolis MN
Stacey Olson - Minneapolis MN
Ting Carlson - Dayton OH
John N. Starr - Chaska MN
Jeffrey J. Kolstad - Wayzata MN
Aharon Eyal - Jerusalem, IL

Assignee:

Cargill Dow Polymers, LLC - Minnetonka MN

International Classification:

C12P 756

US Classification:

435139

Abstract:

Crabtree negative organisms such as Kluyveromyces, Pichia, Hansenula and Candida, are used to make selected organic products such as lactic acid. The organisms are cultured in a first culture medium that includes glucose, under conditions that promote cellular respiration. The organisms are then cultured under a second set of conditions that promote production of the selected organic product. The organisms preferably contain an exogenous lactate dehydrogenase gene.

US Patent:

6534679, Mar 18, 2003

Filed:

Aug 10, 2001

Appl. No.:

09/927116

Inventors:

Aharon M. Eyal - Jerusalem, IL
John N. Starr - Chaska MN
Rod Fisher - Eden Prairie MN
Betty Hazan - Jerusalem, IL
Riki Canari - Beit Zeit, IL
David R. Witzke - Oskaloosa IA
Patrick R. Gruber - Blaine MN
Jeffrey J. Kolstad - Wayzata MN

Assignee:

Cargill, Incorporated - Minneapolis MN

International Classification:

C07C 5908

US Classification:

562589, 562580, 562593, 435139

Abstract:

The techniques for processing lactic acid/lactate salt mixtures are provided. Preferred mixtures for processing are obtained from fermentation broths, preferably from fermentation processes conducted at a pH of 4. 8 or lower. The techniques generally concern the provision of separated lactic acid and lactate streams, from the mixtures. Preferred techniques of separation and processing of each of the streams are provided.

US Patent:

6678627, Jan 13, 2004

Filed:

Jul 30, 2001

Appl. No.:

09/918180

Inventors:

John E. Starr - Plymouth MN 55447

International Classification:

G01L 124

US Classification:

702119

Abstract:

An application program and method for determining the fatigue life of electronic products exposed to vibration, including application program steps of (i) describing the mechanical configuration of the electronic product; (ii) describing the vibration profiles representing environmental exposure; (iii) calculating natural response modes of the circuit card; (iv) calculating stress functions for each component, each response mode; (v) calculating normalized fatigue damage of each component; (vi) removing computer calculation error by comparing the normalized fatigue damage for all components to the expectations; (vii) expectations numerically defined by performing equivalent analyses on test experience results; (viii) for the case of accelerated life testing, using the expectations to determine the adequacy of the design or for the case of product reliability testing, using the expectations to determine the effectiveness of the environmental screen; (ix) for the case of design development, repeating previous steps on design concepts to obtain design configurations capable of meeting design goals.

US Patent:

7026145, Apr 11, 2006

Filed:

Jun 4, 2002

Appl. No.:

10/162935

Inventors:

Joseph Mizrahi - Haifa, IL
Aharon Eyal - Jerusalem, IL
Canari Riki - Jerusalem, IL
Betty Hazan - Jerusalem, IL
John N. Starr - Chaska MN, US

Assignee:

Cargill, Incorporated - Wayzata MN
CSM NV - Amsterdam

International Classification:

C12P 7/56

US Classification:

435139, 562589

Abstract:

The present disclosure provides a process for preparing a purified lactic acid solution suitable for use in connection with a source of lactate material a pH within the range of 0. 8 to 9. The process includes the steps of providing a source of lactate material which includes a calcium salt; acidulating the concentrated broth with sulfuric acid to form an acidulated solution which includes lactic acid and calcium sulfate; reducing an amount of calcium sulfate from the acidulated solution; extracting the acidulated solution with an amine extractant to form a loaded solvent; and back extracting the loaded solvent with an aqueous solvent to provide a purified solution of lactic acid. Optionally, the source of lactate material can be concentrated prior to the step of acidulating. Alternately, the amine extractant can include sulfate anion. The sulfuric anion in the amine extractant can be residual sulfuric acid from the acidulation step.

US Patent:

7144977, Dec 5, 2006

Filed:

Feb 26, 2004

Appl. No.:

10/788696

Inventors:

Aharon M. Eyal - Jerusalem, IL
John N. Starr - Chaska MN, US
Rod Fisher - Eden Prairie MN, US
Betty Hazan - Jerusalem, IL
Riki Canari - Beit Zeit, IL
David R. Witzke - Oskaloosa IA, US
Patrick R. Gruber - Blaine MN, US
Jeffrey J. Kolstad - Wayzata MN, US
Xiangsheng Meng - Chanhassen MN, US

Assignee:

Cargill, Incorporated - Minneapolis MN

International Classification:

C08G 63/08
C07C 59/08
C07C 51/42
C12P 7/56

US Classification:

528354, 562589, 562580, 562593, 435139

Abstract:

The techniques for processing lactic acid/lactate salt mixtures are provided. Preferred mixtures for processing are obtained from fermentation broths, preferably from fermentation processes conducted at a pH of 4. 8 or lower. The techniques generally concern the provision of separated lactic acid and lactate streams, from the mixtures. Preferred techniques of separation and processing of each of the streams are provided.

US Patent:

7229805, Jun 12, 2007

Filed:

Nov 4, 2002

Appl. No.:

10/287564

Inventors:

Vineet Rajgarhia - Minnetonka MN, US
Vassily Hatzimanikatis - Minneapolis MN, US
Stacey Olson - Minneapolis MN, US
Ting Carlson - Dayton OH, US
John N. Starr - Chaska MN, US
Jeffrey J. Kolstad - Wayzata MN, US
Aharon Eyal - Jerusalem, IL

Assignee:

Nature Work, LLP - Minnetonka MN

International Classification:

C12P 7/60
C12N 1/16

US Classification:

435139, 435 41

Abstract:

The invention provides methods and materials related to the production of lactic acid. Specifically, the invention provides methods for producing lactic acid using a crabtree-negative yeast, such as of the and genera, which have been transformed with a lactate dehydrogenase gene.

US Patent:

7700332, Apr 20, 2010

Filed:

Apr 20, 2007

Appl. No.:

11/788839

Inventors:

Vineet Rajgarhia - Minnetonka MN, US
Vassily Hatzimanikatis - Minneapolis MN, US
Stacey Olson - Minneapolis MN, US
Ting Carlson - Dayton OH, US
John N. Starr - Chaska MN, US
Jeffrey J. Kolstad - Wayzata MN, US
Aharon Eyal - Jerusalem, IL

Assignee:

Cargill Inc. - Wayzata MN

International Classification:

C12P 7/60
C12N 1/16

US Classification:

435139, 435 41

Abstract:

The invention provides methods and materials related to the production of lactic acid. Specifically, the invention provides methods for producing lactic acid using a crabtree-negative yeast, such as of the and genera, which have been transformed with a lactate dehydrogenase gene.

US Patent:

20020102672, Aug 1, 2002

Filed:

Oct 4, 1999

Appl. No.:

09/412085

Inventors:

JOSEPH MIZRAHI - HAIFA, IL
AHARON EYAL - JERUSALEM, IL
CANARI RIKI - JERUSALEM, IL
BETTY HAZAN - JERUSALEM, IL
JOHN STARR - CHASKA MN, US

International Classification:

C12P007/56

US Classification:

435/139000

Abstract:

The present disclosure provides a process for preparing a purified lactic acid solution suitable for use in connection with a source of lactate material a pH within the range of 0.8 to 9.0. The process includes the steps of providing a source of lactate material which includes a calcium salt; acidulating the concentrated broth with sulfuric acid to form an acidulated solution which includes lactic acid and calcium sulfate; reducing an amount of calcium sulfate from the acidulated solution; extracting the acidulated solution with an amine extractant to form a loaded solvent; and back extracting the loaded solvent with an aqueous solvent to provide a purified solution of lactic acid. Optionally, the source of lactate material can be concentrated prior to the step of acidulating. Alternately, the amine extractant can include sulfate anion. The sulfuric anion in the amine extractant can be residual sulfuric acid from the acidulation step. Alternately, the sulfuric acid in the amine extractant can be added during the extraction step, for example, as sulfuric acid.