John P Wang

US Patent:

6929637, Aug 16, 2005

Filed:

Dec 11, 2002

Appl. No.:

10/317667

Inventors:

Hugo X. Gonzalez - Woodinville WA, US
Steven Chase Springmeyer - Bellevue WA, US
Richard O. Shea - Kenmore WA, US
John H. Wang - Sammamish WA, US
Lauri J. DeVore - Seattle WA, US

Assignee:

Spiration, Inc. - Redmond WA

International Classification:

A61K009/22

US Classification:

6048901, 604 11

Abstract:

The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. A device includes a flow control member for placement in an air passageway communicating with a lung portion, and when deployed in the air passageway inhibits a therapeutic agent distal of the control member from moving proximal of the control member, and includes the therapeutic agent associated with the flow control member. The control member may inhibit movement of the therapeutic agent by limiting airflow, and may include a one-way valve limiting exhalation of air from the lung portion. The control member may include a flexible membrane impervious to air flow, or a separator arranged to inhibit the movement of the therapeutic agent. The control member may include at least one anchor, and the anchor may be releasable from the air passageway for removal of the intra-bronchial device.

US Patent:

7942931, May 17, 2011

Filed:

Aug 15, 2005

Appl. No.:

11/204383

Inventors:

Hugo X. Gonzalez - Woodinville WA, US
Steven Chase Springmeyer - Bellevue WA, US
Richard O. Shea - Kenmore WA, US
John H. Wang - Sammamish WA, US
Lauri J. DeVore - Seattle WA, US

Assignee:

Spiration, Inc. - Redmond WA

International Classification:

A61F 2/20
A61M 31/00

US Classification:

623 9, 604 9301

Abstract:

The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. A device includes a flow control member for placement in an air passageway communicating with a lung portion, and when deployed in the air passageway inhibits a therapeutic agent distal of the control member from moving proximal of the control member, and includes the therapeutic agent associated with the flow control member. The control member may inhibit movement of the therapeutic agent by limiting airflow, and may include a one-way valve limiting exhalation of air from the lung portion. The control member may include a flexible membrane impervious to air flow, or a separator arranged to inhibit the movement of the therapeutic agent. The control member may include at least one anchor, and the anchor may be releasable from the air passageway for removal of the intra-bronchial device.

US Patent:

8230319, Jul 24, 2012

Filed:

Jan 31, 2008

Appl. No.:

12/024055

Inventors:

William G Morein - Seattle WA, US
Abraham Mathew - Edmonds WA, US
Loic Henry-Greard - Sammamish WA, US
Raveendrnathan Loganathan - Redmond WA, US
Sung Won Shin - Issaquah WA, US
Heidi McAllister - Brier WA, US
John Wang - Kirkland WA, US
Emil Cicos - Kirkland WA, US
Mairead Therese Droney - Seattle WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 17/00

US Classification:

715204, 715201, 715207, 715211, 715765, 715839, 707611, 705 727

Abstract:

Technologies are described herein for refreshing data-linked diagrams on a server computer and viewing and consuming the refreshed diagrams via a Web browser. A drawing program allows equations within a diagram definition to define how external data is utilized to modify the attributes of a diagram element. When the diagram is published to a server computer, the definition is converted to server-legible definition. A published diagram is generated that includes a diagram representation defined by the server-legible definition. Upon a request for the published diagram, the external data is refreshed and the diagram definition is updated. The equations are recalculated to generate new element attributes. The diagram representation is then updated with the new attributes and returned for display by a client Web browser. An interface provides exploration tools and a client API exposes methods for surfacing external data and annotating the diagram.

US Patent:

20020112729, Aug 22, 2002

Filed:

Feb 21, 2001

Appl. No.:

10/081712

Inventors:

Lauri DeVore - Seattle WA, US
Richard Shea - Kenmore WA, US
John Wang - Sammamish WA, US

Assignee:

Spiration, Inc.

International Classification:

A61M016/00
A62B009/02
A62B009/06

US Classification:

128/207150, 128/207160

Abstract:

The present invention provides an intra-bronchial device and method that controls biological interaction of the device with the patient. The intra-bronchial device is adapted to be placed in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion to collapse the lung portion, and a medicant carried by the obstructing member. The medicant may overlie at least a portion of the obstructing member, or the medicant may be absorbed in at least a portion of the obstructing member. The obstructing member may further include an absorptive member, and the medicant is absorbed by the absorptive member.

US Patent:

20030154988, Aug 21, 2003

Filed:

Jun 21, 2002

Appl. No.:

10/178073

Inventors:

Lauri DeVore - Seattle WA, US
Richard Shea - Kenmore WA, US
John Wang - Sammamish WA, US
Hugo Gonzalez - Woodinville WA, US
Steven Springmeyer - Bellevue WA, US

Assignee:

Spiration, Inc.

International Classification:

A61M016/00

US Classification:

128/207150, 604/096010

Abstract:

An intra-bronchial device provides a medicant intra-bronchially. The medicant may be used for controlling biological interaction of an intra-bronchial obstruction device with the patient, to treat a disease or condition of the lungs such as pneumonia or lung cancer, or to treat a systemic disease or condition. The medicant is provided by associating a medicant with the intra-bronchial device, either before, at the time of placement, or after placement. The medicant may overlie at least a portion of the intra-bronchial device, be absorbed into at least a portion of the intra-bronchial device, or be carried in a chamber. The intra-bronchial device may further include an absorptive member, and the medicant is absorbed by the absorptive member.

US Patent:

20060200076, Sep 7, 2006

Filed:

May 3, 2006

Appl. No.:

11/417738

Inventors:

Hugo Gonzalez - Woodinville WA, US
Steven Springmeyer - Bellevue WA, US
Richard Shea - Kenmore WA, US
John Wang - Sammamish WA, US
Lauri DeVore - Seattle WA, US

International Classification:

A61M 29/00

US Classification:

604104000

Abstract:

The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. A device includes a flow control member for placement in an air passageway communicating with a lung portion, and when deployed in the air passageway inhibits a therapeutic agent distal of the control member from moving proximal of the control member, and includes the therapeutic agent associated with the flow control member. The control member may inhibit movement of the therapeutic agent by limiting airflow, and may include a one-way valve limiting exhalation of air from the lung portion. The control member may include a flexible membrane impervious to air flow, or a separator arranged to inhibit the movement of the therapeutic agent. The control member may include at least one anchor, and the anchor may be releasable from the air passageway for removal of the intra-bronchial device.

US Patent:

20060206147, Sep 14, 2006

Filed:

May 3, 2006

Appl. No.:

11/418541

Inventors:

Lauri DeVore - Seattle WA, US
Richard Shea - Kenmore WA, US
John Wang - Sammamish WA, US
Hugo Gonzales - Woodinville WA, US
Steven Springmeyer - Bellevue WA, US

International Classification:

A61B 17/08

US Classification:

606213000

Abstract:

An intra-bronchial device provides a medicant intra-bronchially. The medicant may be used for controlling biological interaction of an intra-bronchial obstruction device with the patient, to treat a disease or condition of the lungs such as pneumonia or lung cancer, or to treat a systemic disease or condition. The medicant is provided by associating a medicant with the intra-bronchial device, either before, at the time of placement, or after placement. The medicant may overlie at least a portion of the intra-bronchial device, be absorbed into at least a portion of the intra-bronchial device, or be carried in a chamber. The intra-bronchial device may further include an absorptive member, and the medicant is absorbed by the absorptive member.

US Patent:

20060235432, Oct 19, 2006

Filed:

May 3, 2006

Appl. No.:

11/417553

Inventors:

Lauri DeVore - Seattle WA, US
Richard Shea - Kenmore WA, US
John Wang - Sammamish WA, US

International Classification:

A61F 11/00

US Classification:

606108000

Abstract:

The present invention provides an intra-bronchial device and method that controls biological interaction of the device with the patient. The intra-bronchial device is adapted to be placed in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion to collapse the lung portion, and a medicant carried by the obstructing member. The medicant may overlie at least a portion of the obstructing member, or the medicant may be absorbed in at least a portion of the obstructing member. The obstructing member may further include an absorptive member, and the medicant is absorbed by the absorptive member.